GO:0031995
JSON
insulin-like growth factor II binding
Molecular Function
Definition (GO:0031995 GONUTS page)
Binding to insulin-like growth factor II.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
IGF-II binding | exact |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0031995 | insulin-like growth factor II binding | Never in Taxon | 2 | Bacteria | |
GO:0031995 | insulin-like growth factor II binding | Never in Taxon | 2157 | Archaea | |
GO:0031995 | insulin-like growth factor II binding | Never in Taxon | 4751 | Fungi |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P21333-1 | 9606 | FLNA_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 | |
NOT-qualified manual | protein | P63026 | 9913 | VAMP2_BOVIN | GO:0005515 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699 | |
NOT-qualified manual | protein | Q86V48 | 9606 | LUZP1_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0031995 based on ALL annotations
The top 100 of 290 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
insulin-like growth factor II binding
|
35,359.84 | 100.00 | 5,513 | 5,513 |
regulation of insulin-like growth factor receptor signaling pathway
|
34,144.90 | 94.58 | 5,396 | 5,588 |
insulin-like growth factor I binding
|
32,398.93 | 91.32 | 5,493 | 5,995 |
insulin-like growth factor binding
|
18,793.82 | 52.25 | 5,340 | 10,047 |
fibronectin binding
|
10,575.29 | 22.36 | 2,590 | 8,660 |
growth factor binding
|
7,631.87 | 20.14 | 4,141 | 19,186 |
positive regulation of insulin-like growth factor receptor signaling pathway
|
10,512.39 | 3.81 | 231 | 777 |
type B pancreatic cell proliferation
|
6,795.44 | 3.56 | 231 | 1,202 |
insulin-like growth factor ternary complex
|
13,953.27 | 2.80 | 161 | 408 |
negative regulation of smooth muscle cell migration
|
6,627.40 | 2.59 | 161 | 859 |
Totals | 47923 | 5223229 |
No co-occurrence statistics for GO:0031995 based on MANUAL annotations
The top 100 of 233 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
insulin-like growth factor II binding
|
11,533.92 | 100.00 | 112 | 112 |
regulation of insulin-like growth factor receptor signaling pathway
|
10,598.74 | 84.30 | 102 | 111 |
insulin-like growth factor I binding
|
9,227.14 | 75.36 | 104 | 130 |
fibronectin binding
|
2,367.22 | 15.99 | 47 | 229 |
insulin-like growth factor binding
|
1,675.87 | 8.02 | 17 | 117 |
insulin-like growth factor receptor activity
|
6,151.42 | 6.72 | 8 | 15 |
clathrin coat
|
3,181.77 | 6.02 | 8 | 29 |
response to tetrachloromethane
|
3,181.77 | 6.02 | 8 | 29 |
nuclear envelope lumen
|
1,845.43 | 5.19 | 8 | 50 |
retromer complex binding
|
1,098.47 | 4.26 | 8 | 84 |
Totals | 689 | 15195 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_chembl | 296 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2157 (Archaea) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2 (Bacteria) |
2021-05-24 | Added | DEFINITION | Binding to insulin-like growth factor II. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with insulin-like growth factor II. |
2015-05-19 | Added | SUBSET | goslim_chembl |
2015-05-19 | Deleted | SUBSET | goslim_ChEMBL |
2015-05-11 | Added | SUBSET | goslim_ChEMBL |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with insulin-like growth factor II. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with insulin-like growth factor II. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2005-12-25 | Added | TERM | insulin-like growth factor II binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Added | DEFINITION | Binding to insulin-like growth factor II. |
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with insulin-like growth factor II. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with insulin-like growth factor II. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with insulin-like growth factor II. |
2008-05-13 | Added | DEFINITION | Interacting selectively with insulin-like growth factor II. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with insulin-like growth factor II. |
2007-08-09 | Deleted | SYNONYM | IGF-II binding |
2007-08-09 | Added | SYNONYM | IGF-II binding |
2005-12-25 | Added | SYNONYM | IGF-II binding |
2005-12-25 | Added | DEFINITION | Interacting selectively with insulin-like growth factor II. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0005520 (insulin-like growth factor binding) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2157 (Archaea) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2 (Bacteria) |
2015-05-19 | Added | SUBSET | goslim_chembl |
2015-05-19 | Deleted | SUBSET | goslim_ChEMBL |
2015-05-11 | Added | SUBSET | goslim_ChEMBL |
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