GO:0032488
JSON
Cdc42 protein signal transduction
Biological Process
Definition (GO:0032488 GONUTS page)
An intracellular signaling cassette in which a small monomeric GTPase of the Cdc42 subfamily relays a signal. PMID:18558478
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| Cdc42 signaling pathway | related |
| Cdc42 signaling | related |
| cdc42 signalling pathway | related |
Ancestor Chart
Ancestor chart for GO:0032488
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0032488
| Child Term | Relationship to GO:0032488 |
|---|---|
|
regulation of Cdc42 protein signal transduction
|
regulates |
GO Discussions
The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:
| Ontology Development Project | |
|---|---|
| signalling | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| NOT-qualified manual | protein | B0BN43 | 10116 | B0BN43_RAT | GO:0007266 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | G3V9K5 | 10116 | G3V9K5_RAT | GO:0007266 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | M0RBE8 | 10116 | M0RBE8_RAT | GO:0007266 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | P42768 | 9606 | WASP_HUMAN | GO:0007266 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:8625410 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0032488 based on ALL annotations
The top 100 of 122 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
Cdc42 protein signal transduction
|
2,085,840.60 | 100.00 | 95 | 95 |
|
regulation of T cell antigen processing and presentation
|
2,085,840.60 | 86.32 | 82 | 82 |
|
actin filament bundle retrograde transport
|
548,905.44 | 4.59 | 5 | 19 |
|
regulation of actin polymerization or depolymerization
|
87,577.54 | 4.17 | 82 | 1,953 |
|
phospholipase binding
|
83,678.54 | 3.99 | 82 | 2,044 |
|
regulation of stress fiber assembly
|
78,278.69 | 3.73 | 82 | 2,185 |
|
negative regulation of cell motility
|
56,170.42 | 2.68 | 82 | 3,045 |
|
regulation of glial cell migration
|
101,748.33 | 2.31 | 4 | 82 |
|
substrate-dependent cell migration, cell extension
|
51,757.83 | 2.05 | 10 | 403 |
|
endoplasmic reticulum polarization
|
65,592.48 | 2.01 | 5 | 159 |
| Totals | 2572 | 6799004 | ||
No co-occurrence statistics for GO:0032488 based on MANUAL annotations
The top 100 of 112 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
Cdc42 protein signal transduction
|
88,220.81 | 100.00 | 16 | 16 |
|
actin filament bundle retrograde transport
|
63,014.87 | 27.78 | 5 | 7 |
|
endoplasmic reticulum polarization
|
55,138.01 | 26.32 | 5 | 8 |
|
regulation of T cell antigen processing and presentation
|
88,220.81 | 25.00 | 4 | 4 |
|
substrate-dependent cell migration, cell extension
|
22,055.20 | 21.74 | 10 | 40 |
|
cytoplasmic actin-based contraction involved in cell motility
|
16,337.19 | 13.16 | 5 | 27 |
|
chemorepulsion of axon
|
18,572.80 | 12.90 | 4 | 19 |
|
netrin-activated signaling pathway
|
15,753.72 | 12.82 | 5 | 28 |
|
regulation of glial cell migration
|
58,813.88 | 11.76 | 2 | 3 |
|
regulation of double-strand break repair via nonhomologous end joining
|
9,286.40 | 8.00 | 4 | 38 |
| Totals | 340 | 131316 | ||
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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- Cross-references
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2023-12-15 | Deleted | DEFINITION | The series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state. |
| 2023-12-15 | Added | DEFINITION | An intracellular signaling cassette in which a small monomeric GTPase of the Cdc42 subfamily relays a signal. |
| 2022-03-14 | Deleted | DEFINITION | A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state. |
| 2022-03-14 | Added | DEFINITION | The series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state. |
| 2011-10-05 | Added | SYNONYM | Cdc42 signaling pathway |
| 2011-10-05 | Added | SYNONYM | cdc42 signalling pathway |
| 2011-10-05 | Added | SYNONYM | Cdc42 signaling |
| 2008-05-13 | Added | DEFINITION | A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state. |
| 2008-05-12 | Deleted | DEFINITION | A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state. |
| 2008-04-01 | Updated | RELATION | is a GO:0007266 (Rho protein signal transduction) |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2006-12-06 | Added | TERM | Cdc42 protein signal transduction |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2023-12-15 | Deleted | DEFINITION | The series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state. |
| 2023-12-15 | Added | DEFINITION | An intracellular signaling cassette in which a small monomeric GTPase of the Cdc42 subfamily relays a signal. |
| 2022-03-14 | Deleted | DEFINITION | A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state. |
| 2022-03-14 | Added | DEFINITION | The series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state. |
| 2011-10-05 | Added | SYNONYM | Cdc42 signaling pathway |
| 2011-10-05 | Added | SYNONYM | cdc42 signalling pathway |
| 2011-10-05 | Added | SYNONYM | Cdc42 signaling |
| 2008-05-13 | Added | DEFINITION | A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state. |
| 2008-05-12 | Deleted | DEFINITION | A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state. |
| 2006-12-06 | Added | DEFINITION | A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-04-01 | Updated | RELATION | is a GO:0007266 (Rho protein signal transduction) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|
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