This term is obsolete.

GO:0032673 JSON

regulation of interleukin-4 production

Biological Process

Definition (GO:0032673 GONUTS page)

Any process that modulates the frequency, rate, or extent of interleukin-4 production. PMID:29778524

Secondary IDs

GO:0045402, GO:0150133

2,280 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
regulation of interleukin-4 secretion narrow
regulation of IL-4 production exact
regulation of interleukin-4 biosynthetic process narrow

Ancestor Chart

Ancestor chart for GO:0032673
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0032673

Child Term Relationship to
GO:0032673
negative regulation of interleukin-4 production
is_a
positive regulation of interleukin-4 production
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to terms describing protein or chemical production Link

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0032673 regulation of interleukin-4 production Never in Taxon 4896 Schizosaccharomyces pombe
GO:0032673 regulation of interleukin-4 production Never in Taxon 4932 Saccharomyces cerevisiae

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein O00182 9606 LEG9_HUMAN GO:0032673 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16116184
NOT-qualified manual protein P97840 10116 LEG9_RAT GO:0032673 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P9WNV7 83332 DNAJ2_MYCTU GO:0010468 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15207487
NOT-qualified manual protein Q90998 9031 Q90998_CHICK GO:0010468 3 NOT-qualified manual annotations exist with evidence code ECO:0000315 from this reference: PMID:11500982
NOT-qualified manual protein Q90999 9031 TGFR2_CHICK GO:0010468 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11500982
NOT-qualified manual protein Q96AE4 9606 FUBP1_HUMAN GO:0010468 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:8125259
NOT-qualified manual protein Q9USK2 284812 SET9_SCHPO GO:0010468 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15550243

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0032673 based on ALL annotations
The top 100 of 155 co-occurring terms
Co-occurring Term PR S% #Together #Compared
regulation of interleukin-4 production
10,829,933.00 100.00 18 18
MHC class II receptor activity
3,766,933.00 24.24 8 23
regulation of interleukin-10 production
1,682,319.60 15.24 16 103
positive regulation of activated T cell autonomous cell death
3,609,977.50 9.09 2 6
antigen processing and presentation of endogenous peptide antigen via MHC class II
1,007,435.56 8.33 8 86
myeloid dendritic cell antigen processing and presentation
995,855.90 8.25 8 87
positive regulation of CD4-positive, alpha-beta T cell activation
759,995.30 6.45 8 114
regulation of T-helper 17 type immune response
1,203,325.90 3.85 1 9
regulation of T-helper cell differentiation
345,177.12 3.07 8 251
negative regulation of natural killer cell degranulation
637,054.90 2.94 1 17
Totals 474 393770
No co-occurrence statistics for GO:0032673 based on MANUAL annotations
The top 100 of 139 co-occurring terms
Co-occurring Term PR S% #Together #Compared
regulation of interleukin-4 production
107,649.92 100.00 12 12
regulation of interleukin-10 production
59,805.51 50.00 10 18
T-helper 1 type immune response
26,256.08 23.26 10 41
positive regulation of activated T cell autonomous cell death
107,649.91 16.67 2 2
positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response
53,824.96 14.29 2 4
detection of bacterium
12,582.46 11.25 9 77
natural killer cell tolerance induction
26,912.48 11.11 2 8
antigen processing and presentation of endogenous peptide antigen via MHC class II
26,912.48 11.11 2 8
regulation of interleukin-5 production
26,912.48 11.11 2 8
myeloid dendritic cell antigen processing and presentation
23,922.21 10.53 2 9
Totals 262 15231

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4932 (Saccharomyces cerevisiae)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe)
2020-06-07 Added SECONDARY GO:0045402 (regulation of interleukin-4 biosynthetic process)
2020-06-07 Added SYNONYM regulation of interleukin-4 secretion
2020-06-07 Added SECONDARY GO:0150133 (regulation of interleukin-4 secretion)
2020-06-07 Added SYNONYM regulation of interleukin-4 biosynthetic process
2008-05-13 Added DEFINITION Any process that modulates the frequency, rate, or extent of interleukin-4 production.
2008-05-12 Deleted DEFINITION Any process that modulates the frequency, rate, or extent of interleukin-4 production.
2008-04-01 Added RELATION regulates GO:0032633 (interleukin-4 production)
2008-04-01 Updated RELATION is a GO:0001817 (regulation of cytokine production)
Timestamp Action Category Detail
2006-12-06 Added TERM regulation of interleukin-4 production
Timestamp Action Category Detail
2020-06-07 Added SYNONYM regulation of interleukin-4 secretion
2020-06-07 Added SYNONYM regulation of interleukin-4 biosynthetic process
2008-05-13 Added DEFINITION Any process that modulates the frequency, rate, or extent of interleukin-4 production.
2008-05-12 Deleted DEFINITION Any process that modulates the frequency, rate, or extent of interleukin-4 production.
2007-08-09 Added SYNONYM regulation of IL-4 production
2007-08-09 Deleted SYNONYM regulation of IL-4 production
2006-12-08 Added SYNONYM regulation of IL-4 production
2006-12-06 Added DEFINITION Any process that modulates the frequency, rate, or extent of interleukin-4 production.
Timestamp Action Category Detail
2008-04-01 Added RELATION regulates GO:0032633 (interleukin-4 production)
2008-04-01 Updated RELATION is a GO:0001817 (regulation of cytokine production)
2008-04-01 Updated RELATION part of GO:0032633 (interleukin-4 production)
2008-04-01 Deleted RELATION part of GO:0032633 (interleukin-4 production)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4932 (Saccharomyces cerevisiae)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe)
2020-06-07 Added SECONDARY GO:0045402 (regulation of interleukin-4 biosynthetic process)
2020-06-07 Added SECONDARY GO:0150133 (regulation of interleukin-4 secretion)
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