GO:0032755
JSON
positive regulation of interleukin-6 production
Biological Process
Definition (GO:0032755 GONUTS page)
Any process that activates or increases the frequency, rate, or extent of interleukin-6 production.
Secondary IDs
GO:0045410, GO:2000778
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
activation of interleukin-6 production | narrow |
stimulation of interleukin-6 production | narrow |
up regulation of interleukin-6 production | exact |
up-regulation of interleukin-6 production | exact |
upregulation of interleukin-6 production | exact |
positive regulation of IL-6 production | exact |
positive regulation of interleukin-6 biosynthetic process | narrow |
positive regulation of interleukin-6 secretion | narrow |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to terms describing protein or chemical production | Link |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0032755 | positive regulation of interleukin-6 production | Only in Taxon | 6072 | Eumetazoa |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A6ID83 | 10116 | A6ID83_RAT | GO:0032675 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D4A3I1 | 10116 | D4A3I1_RAT | GO:0032675 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P9WNV7 | 83332 | DNAJ2_MYCTU | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15207487 | |
NOT-qualified manual | protein | Q7TS55 | 10090 | TNF18_MOUSE | GO:0032675 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:24107315 | |
NOT-qualified manual | protein | Q8IZ20-1 | 9606 | ZN683_HUMAN | GO:0010628 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:26179882 | |
NOT-qualified manual | protein | Q90998 | 9031 | Q90998_CHICK | GO:0010468 | 3 NOT-qualified manual annotations exist with evidence code ECO:0000315 from this reference: PMID:11500982 | |
NOT-qualified manual | protein | Q90999 | 9031 | TGFR2_CHICK | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11500982 | |
NOT-qualified manual | protein | Q96AE4 | 9606 | FUBP1_HUMAN | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:8125259 | |
NOT-qualified manual | protein | Q9USK2 | 284812 | SET9_SCHPO | GO:0010468 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15550243 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0032755 based on ALL annotations
The top 100 of 3,032 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
positive regulation of interleukin-6 production
|
20,945.40 | 100.00 | 9,307 | 9,307 |
pattern recognition receptor activity
|
13,145.85 | 30.51 | 3,467 | 5,524 |
positive regulation of tumor necrosis factor production
|
8,804.26 | 23.84 | 3,306 | 7,865 |
positive regulation of chemokine production
|
13,423.29 | 20.20 | 2,120 | 3,308 |
canonical NF-kappaB signal transduction
|
6,961.72 | 20.04 | 3,121 | 9,390 |
positive regulation of interleukin-8 production
|
9,234.75 | 20.03 | 2,499 | 5,668 |
positive regulation of interleukin-1 beta production
|
10,648.66 | 15.95 | 1,755 | 3,452 |
toll-like receptor signaling pathway
|
4,443.16 | 15.51 | 3,403 | 16,042 |
positive regulation of interleukin-12 production
|
11,988.09 | 15.22 | 1,598 | 2,792 |
positive regulation of macrophage cytokine production
|
10,555.81 | 12.03 | 1,270 | 2,520 |
Totals | 88425 | 609592 |
No co-occurrence statistics for GO:0032755 based on MANUAL annotations
The top 100 of 2,856 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
positive regulation of interleukin-6 production
|
2,593.97 | 100.00 | 498 | 498 |
positive regulation of tumor necrosis factor production
|
1,259.27 | 29.81 | 217 | 447 |
positive regulation of interleukin-8 production
|
1,318.11 | 24.04 | 156 | 307 |
positive regulation of interleukin-12 production
|
1,482.27 | 19.24 | 112 | 196 |
positive regulation of chemokine production
|
1,489.44 | 15.78 | 89 | 155 |
positive regulation of interleukin-1 beta production
|
933.83 | 15.65 | 108 | 300 |
positive regulation of interferon-alpha production
|
1,238.03 | 14.24 | 84 | 176 |
positive regulation of type II interferon production
|
570.46 | 12.13 | 106 | 482 |
positive regulation of macrophage cytokine production
|
1,384.92 | 11.39 | 63 | 118 |
positive regulation of interferon-beta production
|
876.67 | 11.39 | 73 | 216 |
Totals | 4535 | 26303 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-04-04 | Added | CONSTRAINT | in_taxon NCBITaxon:6072 (Eumetazoa) |
2020-06-06 | Added | SECONDARY | GO:0045410 (positive regulation of interleukin-6 biosynthetic process) |
2020-06-06 | Added | SECONDARY | GO:2000778 (positive regulation of interleukin-6 secretion) |
2020-06-06 | Added | SYNONYM | positive regulation of interleukin-6 biosynthetic process |
2020-06-06 | Added | SYNONYM | positive regulation of interleukin-6 secretion |
2008-05-13 | Added | DEFINITION | Any process that activates or increases the frequency, rate, or extent of interleukin-6 production. |
2008-05-12 | Deleted | DEFINITION | Any process that activates or increases the frequency, rate, or extent of interleukin-6 production. |
2008-04-01 | Added | RELATION | positively regulates GO:0032635 (interleukin-6 production) |
2008-04-01 | Updated | RELATION | is a GO:0001819 (positive regulation of cytokine production) |
2008-04-01 | Updated | RELATION | is a GO:0032675 (regulation of interleukin-6 production) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2006-12-06 | Added | TERM | positive regulation of interleukin-6 production |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-06-06 | Added | SYNONYM | positive regulation of interleukin-6 biosynthetic process |
2020-06-06 | Added | SYNONYM | positive regulation of interleukin-6 secretion |
2008-05-13 | Added | DEFINITION | Any process that activates or increases the frequency, rate, or extent of interleukin-6 production. |
2008-05-12 | Deleted | DEFINITION | Any process that activates or increases the frequency, rate, or extent of interleukin-6 production. |
2007-08-09 | Deleted | SYNONYM | positive regulation of IL-6 production |
2007-08-09 | Deleted | SYNONYM | stimulation of interleukin-6 production |
2007-08-09 | Deleted | SYNONYM | activation of interleukin-6 production |
2007-08-09 | Added | SYNONYM | stimulation of interleukin-6 production |
2007-08-09 | Added | SYNONYM | up regulation of interleukin-6 production |
2007-08-09 | Deleted | SYNONYM | up regulation of interleukin-6 production |
2007-08-09 | Added | SYNONYM | upregulation of interleukin-6 production |
2007-08-09 | Added | SYNONYM | positive regulation of IL-6 production |
2007-08-09 | Added | SYNONYM | activation of interleukin-6 production |
2007-08-09 | Deleted | SYNONYM | upregulation of interleukin-6 production |
2007-08-09 | Deleted | SYNONYM | up-regulation of interleukin-6 production |
2007-08-09 | Added | SYNONYM | up-regulation of interleukin-6 production |
2007-02-23 | Added | SYNONYM | up regulation of interleukin-6 production |
2007-02-23 | Added | SYNONYM | up-regulation of interleukin-6 production |
2007-02-23 | Added | SYNONYM | upregulation of interleukin-6 production |
2007-02-23 | Added | SYNONYM | activation of interleukin-6 production |
2007-02-23 | Added | SYNONYM | stimulation of interleukin-6 production |
2006-12-08 | Added | SYNONYM | positive regulation of IL-6 production |
2006-12-06 | Added | DEFINITION | Any process that activates or increases the frequency, rate, or extent of interleukin-6 production. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Added | RELATION | positively regulates GO:0032635 (interleukin-6 production) |
2008-04-01 | Updated | RELATION | is a GO:0001819 (positive regulation of cytokine production) |
2008-04-01 | Updated | RELATION | is a GO:0032675 (regulation of interleukin-6 production) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-04-04 | Added | CONSTRAINT | in_taxon NCBITaxon:6072 (Eumetazoa) |
2020-06-06 | Added | SECONDARY | GO:0045410 (positive regulation of interleukin-6 biosynthetic process) |
2020-06-06 | Added | SECONDARY | GO:2000778 (positive regulation of interleukin-6 secretion) |
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