This term is obsolete.
Annotation to this term should be done with caution, particularly if the mechanism is not well clarified.

GO:0032976 JSON

release of matrix enzymes from mitochondria

Biological Process

Definition (GO:0032976 GONUTS page)

The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol, as part of the apoptotic process. PMID:9843949

Comments

Annotation to this term should be done with caution, particularly if the mechanism is not well clarified.

88 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
mAST release from mitochondria narrow
release of aspartate aminotransferase from mitochondria narrow

Ancestor Chart

Ancestor chart for GO:0032976
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating cell death and apoptosis using the new guidelines Link

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0032976 release of matrix enzymes from mitochondria Never in Taxon 4896 Schizosaccharomyces pombe
GO:0032976 release of matrix enzymes from mitochondria Only in Taxon 33154 Opisthokonta

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A1D5Q3B3 9544 A0A1D5Q3B3_MACMU GO:0006915 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2I2YB08 9595 A0A2I2YB08_GORGO GO:0006915 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2J8LBR9 9598 A0A2J8LBR9_PANTR GO:0006915 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2U9DQQ6 7955 A0A2U9DQQ6_DANRE GO:0006915 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A3Q2LIL1 9796 A0A3Q2LIL1_HORSE GO:0006915 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A9L0RP63 9796 A0A9L0RP63_HORSE GO:0006915 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B2RYC9 10116 B2RYC9_RAT GO:0007005 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein B8A526 7955 B8A526_DANRE GO:0006915 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein F1SV36 9823 F1SV36_PIG GO:0006915 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein F1SV37 9823 F1SV37_PIG GO:0006915 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0032976 based on ALL annotations
The top 100 of 152 co-occurring terms
Co-occurring Term PR S% #Together #Compared
release of matrix enzymes from mitochondria
2,436,734.80 100.00 80 80
BAX complex
2,293,397.50 94.12 80 85
T cell homeostatic proliferation
2,178,293.20 67.82 59 66
positive regulation of apoptotic DNA fragmentation
1,131,902.60 44.17 72 155
BAK complex
1,063,302.50 41.62 72 165
B cell receptor apoptotic signaling pathway
1,020,028.50 40.00 72 172
B cell negative selection
984,707.90 35.33 59 146
apoptotic process involved in mammary gland involution
996,037.56 34.78 56 137
positive regulation of apoptotic process involved in mammary gland involution
952,101.70 34.30 59 151
positive regulation of developmental pigmentation
945,837.90 34.10 59 152
Totals 6108 438063
No co-occurrence statistics for GO:0032976 based on MANUAL annotations
The top 100 of 150 co-occurring terms
Co-occurring Term PR S% #Together #Compared
BAX complex
92,271.35 100.00 14 14
release of matrix enzymes from mitochondria
92,271.35 100.00 14 14
BH3 domain binding
47,981.11 50.00 13 25
mitochondrial permeability transition pore complex
30,757.12 33.33 14 42
Bcl-2 family protein complex
30,041.84 32.56 14 43
establishment or maintenance of transmembrane electrochemical gradient
30,041.84 32.56 14 43
mitochondrial fragmentation involved in apoptotic process
21,894.90 23.73 14 59
B cell apoptotic process
19,873.83 21.54 14 65
negative regulation of protein binding
16,776.61 18.18 14 77
pore complex
16,351.89 17.72 14 79
Totals 497 15888

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe)
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:33154 (Opisthokonta)
2012-11-17 Added DEFINITION The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol, as part of the apoptotic process.
2012-11-17 Deleted DEFINITION The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol.
2010-12-01 Deleted DEFINITION The process by which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol.
2010-12-01 Added DEFINITION The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol.
2008-05-13 Added DEFINITION The process by which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol.
2008-05-12 Deleted DEFINITION The process by which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol.
2008-04-01 Updated RELATION is a GO:0008637 (apoptotic mitochondrial changes)
2007-08-09 Added SYNONYM mAST release from mitochondria
Timestamp Action Category Detail
2007-02-24 Added TERM release of matrix enzymes from mitochondria
Timestamp Action Category Detail
2012-11-17 Added DEFINITION The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol, as part of the apoptotic process.
2012-11-17 Deleted DEFINITION The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol.
2010-12-01 Deleted DEFINITION The process by which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol.
2010-12-01 Added DEFINITION The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol.
2008-05-13 Added DEFINITION The process by which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol.
2008-05-12 Deleted DEFINITION The process by which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol.
2007-08-09 Added SYNONYM mAST release from mitochondria
2007-08-09 Deleted SYNONYM mAST release from mitochondria
2007-08-09 Added SYNONYM release of aspartate aminotransferase from mitochondria
2007-08-09 Deleted SYNONYM release of aspartate aminotransferase from mitochondria
2007-02-27 Added DEFINITION The process by which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol.
2007-02-24 Added SYNONYM mAST release from mitochondria
2007-02-24 Added SYNONYM release of aspartate aminotransferase from mitochondria
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0008637 (apoptotic mitochondrial changes)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe)
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:33154 (Opisthokonta)
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