This term is obsolete.

GO:0032980 JSON

keratinocyte activation

Biological Process

Definition (GO:0032980 GONUTS page)

A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines. PMID:15737202

155 annotations

Ancestor Chart

Ancestor chart for GO:0032980
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Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0032980 keratinocyte activation Never in Taxon 6656 Arthropoda
GO:0032980 keratinocyte activation Only in Taxon 33208 Metazoa

More information on taxon constraints in GO is available here

Cross-Ontology Relations

Relation Other Ontology ID Term
has_primary_input CL CL:0000312 keratinocyte

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0032980 based on ALL annotations
The top 79 of 79 co-occurring terms
Co-occurring Term PR S% #Together #Compared
keratinocyte activation
1,286,719.90 100.00 154 154
lymphocyte activation involved in immune response
1,286,719.90 64.94 100 100
B cell receptor apoptotic signaling pathway
748,092.94 44.25 100 172
response to cisplatin
706,988.94 42.37 100 182
positive regulation of T-helper 17 cell differentiation
584,872.70 36.50 100 220
response to Gram-positive bacterium
523,056.88 33.33 100 246
response to folic acid
523,056.88 33.33 100 246
T-helper 17 cell differentiation
324,929.25 22.22 100 396
positive regulation of epidermis development
420,963.90 20.15 53 162
plasma cell differentiation
298,426.00 18.83 77 332
Totals 6580 147187238
No co-occurrence statistics for GO:0032980 based on MANUAL annotations
The top 74 of 74 co-occurring terms
Co-occurring Term PR S% #Together #Compared
keratinocyte activation
235,255.50 100.00 6 6
lymphocyte activation involved in immune response
235,255.52 66.67 4 4
transcription preinitiation complex assembly
235,255.52 66.67 4 4
B cell receptor apoptotic signaling pathway
156,837.00 50.00 4 6
plasma cell differentiation
49,527.48 19.05 4 19
positive regulation of T-helper 17 cell differentiation
47,051.10 18.18 4 20
response to cisplatin
39,209.25 15.38 4 24
T-helper 17 cell differentiation
33,607.93 13.33 4 28
skin epidermis development
29,406.94 11.76 4 32
response to Gram-positive bacterium
28,515.82 11.43 4 33
Totals 246 800466

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2020-10-12 Added CONSTRAINT never_in_taxon NCBITaxon:6656 (Arthropoda)
2010-04-25 Deleted RELATION part of GO:0048699 (generation of neurons)
2008-05-13 Added DEFINITION A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.
2008-05-12 Deleted DEFINITION A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.
2008-04-01 Updated RELATION part of GO:0048699 (generation of neurons)
2008-04-01 Updated RELATION is a GO:0001775 (cell activation)
2007-03-06 Added DEFINITION A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.
2007-03-05 Added TERM keratinocyte activation
Timestamp Action Category Detail
2007-03-05 Added TERM keratinocyte activation
Timestamp Action Category Detail
2008-05-13 Added DEFINITION A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.
2008-05-12 Deleted DEFINITION A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.
2007-03-06 Added DEFINITION A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.
Timestamp Action Category Detail
2010-04-25 Deleted RELATION part of GO:0048699 (generation of neurons)
2008-04-01 Updated RELATION part of GO:0048699 (generation of neurons)
2008-04-01 Updated RELATION is a GO:0001775 (cell activation)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2020-10-12 Added CONSTRAINT never_in_taxon NCBITaxon:6656 (Arthropoda)
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