This term is obsolete.
Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.

GO:0033085 JSON

negative regulation of T cell differentiation in thymus

Biological Process

Definition (GO:0033085 GONUTS page)

Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus.

Comments

Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.

992 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
negative regulation of thymocyte cell differentiation exact
negative regulation of T cell development in thymus related
negative regulation of thymic T cell differentiation exact
negative regulation of thymocyte differentiation exact

Ancestor Chart

Ancestor chart for GO:0033085
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0033085

Child Term Relationship to
GO:0033085
negative regulation of immature T cell proliferation in thymus
is_a
negative regulation of positive thymic T cell selection
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0033085 negative regulation of T cell differentiation in thymus Never in Taxon 4890 Ascomycota

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A6K9T7 10116 A6K9T7_RAT GO:0033081 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A8VU90 10090 ANKL1_MOUSE GO:0033081 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27010503
NOT-qualified manual protein D4A332 10116 D4A332_RAT GO:0033081 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein O08573 10090 LEG9_MOUSE GO:0033081 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:25065622
NOT-qualified manual protein P16047 9031 TGFB3_CHICK GO:0007162 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:17587820
NOT-qualified manual protein P97840 10116 LEG9_RAT GO:0033081 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q90999 9031 TGFR2_CHICK GO:0007162 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:17587820
NOT-qualified manual protein Q90999 9031 TGFR2_CHICK GO:0022408 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:11500982

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0033085 based on ALL annotations
The top 100 of 567 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of T cell differentiation in thymus
432,236.78 100.00 451 451
negative regulation of alpha-beta T cell differentiation
297,723.25 31.56 166 241
negative regulation of immature T cell proliferation in thymus
185,521.86 27.09 191 445
epithelial-mesenchymal cell signaling
208,114.00 26.70 169 351
trachea development
184,952.38 26.12 181 423
bud dilation involved in lung branching
432,236.78 22.84 103 103
negative regulation of glomerulus development
420,003.66 22.69 103 106
negative regulation of metanephric comma-shaped body morphogenesis
416,078.38 22.64 103 107
negative regulation of metanephric S-shaped body morphogenesis
416,078.38 22.64 103 107
intermediate mesodermal cell differentiation
416,078.38 22.64 103 107
Totals 10353 30094
No co-occurrence statistics for GO:0033085 based on MANUAL annotations
The top 100 of 517 co-occurring terms
Co-occurring Term PR S% #Together #Compared
negative regulation of T cell differentiation in thymus
53,824.96 100.00 24 24
positive regulation of thymocyte apoptotic process
21,529.98 22.22 8 20
negative regulation of alpha-beta T cell differentiation
32,294.98 21.43 6 10
B cell homeostatic proliferation
30,757.12 14.81 4 7
negative regulation of immature T cell proliferation in thymus
14,041.29 14.63 6 23
camera-type eye photoreceptor cell fate commitment
53,824.96 12.50 3 3
negative regulation of eye pigmentation
53,824.96 12.50 3 3
central tolerance induction
53,824.96 12.50 3 3
positive regulation of central B cell tolerance induction
53,824.96 12.50 3 3
positive regulation of alpha-beta T cell differentiation
10,417.73 12.24 6 31
Totals 292 1718

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4890 (Ascomycota)
2017-01-12 Deleted RELATION is a GO:2000399 (negative regulation of thymocyte aggregation)
2015-03-19 Added RELATION is a GO:2000399 (negative regulation of thymocyte aggregation)
2010-10-15 Added SYNONYM negative regulation of T cell development in thymus
2010-10-06 Updated TERM negative regulation of T cell differentiation in thymus
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of T cell differentiation in the thymus.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus.
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of T cell differentiation in the thymus.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of T cell differentiation in the thymus.
2008-04-01 Updated RELATION is a GO:0033081 (regulation of T cell differentiation in thymus)
Timestamp Action Category Detail
2010-10-06 Updated TERM negative regulation of T cell differentiation in thymus
2007-03-30 Added TERM negative regulation of T cell differentiation in the thymus
Timestamp Action Category Detail
2010-10-15 Added SYNONYM negative regulation of T cell development in thymus
2010-10-03 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of T cell differentiation in the thymus.
2010-10-03 Added DEFINITION Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus.
2008-05-13 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of T cell differentiation in the thymus.
2008-05-12 Deleted DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of T cell differentiation in the thymus.
2007-08-09 Deleted SYNONYM negative regulation of thymocyte cell differentiation
2007-08-09 Added SYNONYM negative regulation of thymocyte cell differentiation
2007-08-09 Deleted SYNONYM negative regulation of thymic T cell differentiation
2007-08-09 Deleted SYNONYM negative regulation of thymocyte differentiation
2007-08-09 Added SYNONYM negative regulation of thymic T cell differentiation
2007-08-09 Added SYNONYM negative regulation of thymocyte differentiation
2007-04-20 Added DEFINITION Any process that stops, prevents or reduces the frequency, rate or extent of T cell differentiation in the thymus.
2007-03-30 Added SYNONYM negative regulation of thymocyte differentiation
2007-03-30 Added SYNONYM negative regulation of thymocyte cell differentiation
2007-03-30 Added SYNONYM negative regulation of thymic T cell differentiation
Timestamp Action Category Detail
2017-01-12 Deleted RELATION is a GO:2000399 (negative regulation of thymocyte aggregation)
2015-03-19 Added RELATION is a GO:2000399 (negative regulation of thymocyte aggregation)
2008-04-01 Updated RELATION is a GO:0033081 (regulation of T cell differentiation in thymus)
2008-04-01 Updated RELATION is a GO:0045581 (negative regulation of T cell differentiation)
2008-04-01 Added RELATION negatively regulates GO:0033077 (T cell differentiation in thymus)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4890 (Ascomycota)
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