GO:0033094
JSON
putrescine--2-oxoglutarate transaminase activity
Molecular Function
Definition (GO:0033094 GONUTS page)
Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O. The enzymatic part of the reaction produces 4-aminobutanal that spontaneously cyclizes to form 1-pyrroline.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
putrescine aminotransferase activity | broad |
putrescine transaminase activity | broad |
YgjG | related |
putrescine-alpha-ketoglutarate transaminase activity | related |
putrescine:2-oxoglutarate aminotransferase activity | related |
PAT activity | related |
putrescine:alpha-ketoglutarate aminotransferase activity | related |
butane-1,4-diamine:2-oxoglutarate aminotransferase activity | related |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q0E8K5 | 7227 | Q0E8K5_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7JY99 | 7227 | Q7JY99_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7KV84 | 7227 | Q7KV84_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7YTX2 | 7227 | Q7YTX2_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I939 | 7227 | Q8I939_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I940 | 7227 | Q8I940_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.6.1.82 | |
InterPro | IPR017747 | Putrescine aminotransferase |
MetaCyc | PUTTRANSAM-RXN | |
RHEA | 12268 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:15377 | water |
has_participant | CHEBI | CHEBI:36781 | 1-pyrrolinium |
has_participant | CHEBI | CHEBI:29985 | L-glutamate(1-) |
has_participant | CHEBI | CHEBI:326268 | 1,4-butanediammonium |
has_participant | CHEBI | CHEBI:16810 | 2-oxoglutarate(2-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0033094 based on ALL annotations
The top 33 of 33 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
putrescine--2-oxoglutarate transaminase activity
|
74,918.83 | 100.00 | 2,602 | 2,602 |
putrescine catabolic process
|
36,285.83 | 45.41 | 2,288 | 4,724 |
diamine transaminase activity
|
74,503.54 | 34.41 | 897 | 902 |
L-lysine catabolic process
|
19,512.45 | 19.43 | 1,128 | 4,331 |
identical protein binding
|
425.65 | 0.57 | 2,537 | 446,538 |
transaminase activity
|
161.37 | 0.22 | 2,602 | 1,208,015 |
ornithine aminotransferase activity
|
180.57 | 0.21 | 38 | 15,766 |
pyridoxal phosphate binding
|
111.41 | 0.15 | 2,570 | 1,728,166 |
(R)-3-amino-2-methylpropionate-pyruvate transaminase activity
|
1,248.65 | 0.07 | 2 | 120 |
N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
|
16.98 | 0.02 | 7 | 30,888 |
Totals | 14751 | 148902900 |
No co-occurrence statistics for GO:0033094 based on MANUAL annotations
The top 6 of 6 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
putrescine--2-oxoglutarate transaminase activity
|
645,899.50 | 100.00 | 2 | 2 |
putrescine catabolic process
|
56,165.18 | 8.70 | 2 | 23 |
pyridoxal phosphate binding
|
583.73 | 0.09 | 2 | 2,213 |
identical protein binding
|
147.13 | 0.02 | 2 | 8,780 |
protein homodimerization activity
|
121.43 | 0.02 | 1 | 5,319 |
cytosol
|
7.67 | 0.00 | 1 | 84,217 |
Totals | 10 | 100554 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-09-12 | Deleted | DEFINITION | Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O. |
2023-09-12 | Added | DEFINITION | Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O. The enzymatic part of the reaction produces 4-aminobutanal that spontaneously cyclizes to form 1-pyrroline. |
2023-09-12 | Added | SYNONYM | butane-1,4-diamine:2-oxoglutarate aminotransferase activity |
2023-09-12 | Updated | TERM | putrescine--2-oxoglutarate transaminase activity |
2023-08-11 | Deleted | XREF | MetaCyc:2.6.1.82-RXN |
2023-08-11 | Added | XREF | MetaCyc:PUTTRANSAM-RXN |
2020-10-08 | Deleted | SYNONYM | putrescine-alpha-ketoglutarate transaminase activity |
2020-10-08 | Added | SYNONYM | putrescine:2-oxoglutarate aminotransferase activity |
2020-10-08 | Added | SYNONYM | putrescine-alpha-ketoglutarate transaminase activity |
2020-10-08 | Added | SYNONYM | putrescine:alpha-ketoglutarate aminotransferase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-09-12 | Updated | TERM | putrescine--2-oxoglutarate transaminase activity |
2009-03-29 | Updated | TERM | butane-1,4-diamine:2-oxoglutarate aminotransferase activity |
2007-04-01 | Added | TERM | putrescine aminotransferase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-09-12 | Deleted | DEFINITION | Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O. |
2023-09-12 | Added | DEFINITION | Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O. The enzymatic part of the reaction produces 4-aminobutanal that spontaneously cyclizes to form 1-pyrroline. |
2023-09-12 | Added | SYNONYM | butane-1,4-diamine:2-oxoglutarate aminotransferase activity |
2020-10-08 | Deleted | SYNONYM | putrescine-alpha-ketoglutarate transaminase activity |
2020-10-08 | Added | SYNONYM | putrescine:2-oxoglutarate aminotransferase activity |
2020-10-08 | Added | SYNONYM | putrescine-alpha-ketoglutarate transaminase activity |
2020-10-08 | Added | SYNONYM | putrescine:alpha-ketoglutarate aminotransferase activity |
2020-10-08 | Deleted | SYNONYM | putrescine:2-oxoglutarate aminotransferase activity |
2020-10-08 | Deleted | SYNONYM | putrescine:alpha-ketoglutarate aminotransferase activity |
2010-09-15 | Added | DEFINITION | Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O. |
2010-09-15 | Deleted | DEFINITION | Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H(2)O. |
2009-03-29 | Deleted | SYNONYM | putrescine transaminase activity |
2009-03-29 | Deleted | SYNONYM | butane-1,4-diamine:2-oxoglutarate aminotransferase activity |
2009-03-29 | Added | SYNONYM | PAT activity |
2009-03-29 | Added | SYNONYM | putrescine aminotransferase activity |
2009-03-29 | Added | SYNONYM | putrescine transaminase activity |
2009-03-29 | Deleted | SYNONYM | PAT activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H(2)O. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H(2)O. |
2007-11-08 | Added | SYNONYM | putrescine:alpha-ketoglutarate aminotransferase activity |
2007-11-08 | Added | SYNONYM | putrescine:2-oxoglutarate aminotransferase activity |
2007-11-08 | Added | SYNONYM | butane-1,4-diamine:2-oxoglutarate aminotransferase activity |
2007-11-08 | Added | SYNONYM | YgjG |
2007-09-06 | Deleted | SYNONYM | putrescine-alpha-ketoglutarate transaminase |
2007-09-06 | Added | SYNONYM | putrescine-alpha-ketoglutarate transaminase activity |
2007-08-09 | Deleted | SYNONYM | PAT activity |
2007-08-09 | Added | SYNONYM | putrescine-alpha-ketoglutarate transaminase |
2007-08-09 | Deleted | SYNONYM | putrescine-alpha-ketoglutarate transaminase |
2007-08-09 | Added | SYNONYM | PAT activity |
2007-08-09 | Added | SYNONYM | putrescine transaminase activity |
2007-08-09 | Deleted | SYNONYM | putrescine transaminase activity |
2007-04-20 | Added | DEFINITION | Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H(2)O. |
2007-04-01 | Added | SYNONYM | putrescine-alpha-ketoglutarate transaminase |
2007-04-01 | Added | SYNONYM | putrescine transaminase activity |
2007-04-01 | Added | SYNONYM | PAT activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0008483 (transaminase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-08-11 | Deleted | XREF | MetaCyc:2.6.1.82-RXN |
2023-08-11 | Added | XREF | MetaCyc:PUTTRANSAM-RXN |
2020-03-29 | Deleted | XREF | RHEA:24655 |
2020-03-29 | Added | XREF | RHEA:12268 |
2011-09-16 | Added | XREF | RHEA:24655 |
2009-05-21 | Added | XREF | MetaCyc:2.6.1.82-RXN |
2007-04-01 | Added | XREF | EC:2.6.1.82 |
Timestamp | Action | Category | Detail |
---|
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