This term is obsolete.

GO:0033152 JSON

immunoglobulin V(D)J recombination

Biological Process

Definition (GO:0033152 GONUTS page)

The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.

4,650 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
immunoglobulin V-D-J recombination narrow
immunoglobulin V-J joining narrow
immunoglobulin V-J recombination narrow
immunoglobulin V(D)J joining exact
immunoglobulin V-D-J joining narrow

Ancestor Chart

Ancestor chart for GO:0033152
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0033152

Child Term Relationship to
GO:0033152
immunoglobulin light chain V-J recombination
is_a
immunoglobulin heavy chain V-D-J recombination
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0033152 immunoglobulin V(D)J recombination Never in Taxon 2 Bacteria
GO:0033152 immunoglobulin V(D)J recombination Never in Taxon 2157 Archaea
GO:0033152 immunoglobulin V(D)J recombination Never in Taxon 4751 Fungi
GO:0033152 immunoglobulin V(D)J recombination Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MKE9 10116 A0A096MKE9_RAT GO:0033151 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2JV76 10116 A0A0G2JV76_RAT GO:0033151 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6HHE1 10116 A6HHE1_RAT GO:0033151 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein F7FP17 10116 F7FP17_RAT GO:0033151 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein P18858 9606 DNLI1_HUMAN GO:0033151 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:9809069
NOT-qualified manual protein P49916 9606 DNLI3_HUMAN GO:0033151 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:9809069
NOT-qualified manual protein Q5U2M4 10116 Q5U2M4_RAT GO:0033151 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q9JHY8 10116 DNLI1_RAT GO:0033151 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0033152 based on ALL annotations
The top 100 of 289 co-occurring terms
Co-occurring Term PR S% #Together #Compared
immunoglobulin V(D)J recombination
44,274.08 100.00 4,403 4,403
DNA-dependent protein kinase-DNA ligase 4 complex
24,639.16 39.94 2,580 4,636
DNA ligation involved in DNA repair
12,827.26 23.73 2,498 8,622
DNA ligase IV complex
10,699.00 20.38 2,490 10,304
response to X-ray
16,935.75 19.01 1,208 3,158
nonhomologous end joining complex
12,423.68 6.90 369 1,315
intrinsic apoptotic signaling pathway in response to DNA damage
3,485.61 6.60 1,275 16,195
nucleotide-excision repair, DNA gap filling
2,349.86 4.71 1,303 24,550
double-strand break repair via nonhomologous end joining
2,047.06 4.57 3,482 75,309
T cell receptor V(D)J recombination
23,207.28 4.49 206 393
Totals 41499 6795654
No co-occurrence statistics for GO:0033152 based on MANUAL annotations
The top 100 of 239 co-occurring terms
Co-occurring Term PR S% #Together #Compared
immunoglobulin V(D)J recombination
16,147.49 100.00 80 80
DNA-dependent protein kinase-DNA ligase 4 complex
5,733.53 28.99 49 138
DNA ligation involved in DNA repair
4,791.01 18.75 27 91
nonhomologous end joining complex
5,382.50 17.74 22 66
DNA ligase IV complex
3,245.33 16.87 41 204
pro-B cell differentiation
9,541.70 14.61 13 22
response to X-ray
2,094.81 9.96 24 185
T cell receptor V(D)J recombination
5,011.29 9.00 9 29
DN2 thymocyte differentiation
7,176.66 8.89 8 18
V(D)J recombination
2,430.80 8.81 14 93
Totals 815 14200

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:2157 (Archaea)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:2 (Bacteria)
2010-12-01 Deleted DEFINITION The process by which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.
2010-12-01 Added DEFINITION The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.
2010-03-11 Deleted SYNONYM immunoglobulin V-D-J joining
2010-03-11 Deleted DEFINITION The process by which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin light chains the same process is used to join V and J gene segments directly.
2010-03-11 Added DEFINITION The process by which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.
2010-03-11 Deleted SYNONYM immunoglobulin V-J joining
Timestamp Action Category Detail
2007-04-14 Added TERM immunoglobulin V(D)J recombination
Timestamp Action Category Detail
2010-12-01 Deleted DEFINITION The process by which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.
2010-12-01 Added DEFINITION The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.
2010-03-11 Deleted SYNONYM immunoglobulin V-D-J joining
2010-03-11 Deleted DEFINITION The process by which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin light chains the same process is used to join V and J gene segments directly.
2010-03-11 Added DEFINITION The process by which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.
2010-03-11 Deleted SYNONYM immunoglobulin V-J joining
2010-03-11 Deleted SYNONYM immunoglobulin V-J recombination
2010-03-11 Deleted SYNONYM immunoglobulin V-D-J recombination
2010-03-11 Added SYNONYM immunoglobulin V-D-J recombination
2010-03-11 Added SYNONYM immunoglobulin V-J recombination
2010-03-11 Added SYNONYM immunoglobulin V-D-J joining
2010-03-11 Added SYNONYM immunoglobulin V-J joining
2008-05-13 Added DEFINITION The process by which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin light chains the same process is used to join V and J gene segments directly.
2008-05-12 Deleted DEFINITION The process by which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin light chains the same process is used to join V and J gene segments directly.
2007-08-09 Deleted SYNONYM immunoglobulin V-D-J recombination
2007-08-09 Added SYNONYM immunoglobulin V(D)J joining
2007-08-09 Deleted SYNONYM immunoglobulin V-J joining
2007-08-09 Deleted SYNONYM immunoglobulin V(D)J joining
2007-08-09 Deleted SYNONYM immunoglobulin V-D-J joining
2007-08-09 Deleted SYNONYM immunoglobulin V-J recombination
2007-08-09 Added SYNONYM immunoglobulin V-D-J joining
2007-08-09 Added SYNONYM immunoglobulin V-D-J recombination
2007-08-09 Added SYNONYM immunoglobulin V-J joining
2007-08-09 Added SYNONYM immunoglobulin V-J recombination
2007-04-20 Added DEFINITION The process by which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin light chains the same process is used to join V and J gene segments directly.
2007-04-14 Added SYNONYM immunoglobulin V-J joining
2007-04-14 Added SYNONYM immunoglobulin V(D)J joining
2007-04-14 Added SYNONYM immunoglobulin V-J recombination
2007-04-14 Added SYNONYM immunoglobulin V-D-J recombination
2007-04-14 Added SYNONYM immunoglobulin V-D-J joining
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016447 (somatic recombination of immunoglobulin gene segments)
2008-04-01 Updated RELATION is a GO:0033151 (V(D)J recombination)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:2157 (Archaea)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:2 (Bacteria)
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