GO:0033152
JSON
immunoglobulin V(D)J recombination
Biological Process
Definition (GO:0033152 GONUTS page)
The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
immunoglobulin V-D-J recombination | narrow |
immunoglobulin V-J joining | narrow |
immunoglobulin V-J recombination | narrow |
immunoglobulin V(D)J joining | exact |
immunoglobulin V-D-J joining | narrow |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0033152
Child Term | Relationship to GO:0033152 |
---|---|
immunoglobulin light chain V-J recombination
|
is_a |
immunoglobulin heavy chain V-D-J recombination
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0033152 | immunoglobulin V(D)J recombination | Never in Taxon | 2 | Bacteria | |
GO:0033152 | immunoglobulin V(D)J recombination | Never in Taxon | 2157 | Archaea | |
GO:0033152 | immunoglobulin V(D)J recombination | Never in Taxon | 4751 | Fungi | |
GO:0033152 | immunoglobulin V(D)J recombination | Only in Taxon | 131567 | cellular organisms |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A096MKE9 | 10116 | A0A096MKE9_RAT | GO:0033151 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2JV76 | 10116 | A0A0G2JV76_RAT | GO:0033151 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6HHE1 | 10116 | A6HHE1_RAT | GO:0033151 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | F7FP17 | 10116 | F7FP17_RAT | GO:0033151 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | P18858 | 9606 | DNLI1_HUMAN | GO:0033151 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:9809069 | |
NOT-qualified manual | protein | P49916 | 9606 | DNLI3_HUMAN | GO:0033151 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:9809069 | |
NOT-qualified manual | protein | Q5U2M4 | 10116 | Q5U2M4_RAT | GO:0033151 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q9JHY8 | 10116 | DNLI1_RAT | GO:0033151 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0033152 based on ALL annotations
The top 100 of 289 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
immunoglobulin V(D)J recombination
|
44,274.08 | 100.00 | 4,403 | 4,403 |
DNA-dependent protein kinase-DNA ligase 4 complex
|
24,639.16 | 39.94 | 2,580 | 4,636 |
DNA ligation involved in DNA repair
|
12,827.26 | 23.73 | 2,498 | 8,622 |
DNA ligase IV complex
|
10,699.00 | 20.38 | 2,490 | 10,304 |
response to X-ray
|
16,935.75 | 19.01 | 1,208 | 3,158 |
nonhomologous end joining complex
|
12,423.68 | 6.90 | 369 | 1,315 |
intrinsic apoptotic signaling pathway in response to DNA damage
|
3,485.61 | 6.60 | 1,275 | 16,195 |
nucleotide-excision repair, DNA gap filling
|
2,349.86 | 4.71 | 1,303 | 24,550 |
double-strand break repair via nonhomologous end joining
|
2,047.06 | 4.57 | 3,482 | 75,309 |
T cell receptor V(D)J recombination
|
23,207.28 | 4.49 | 206 | 393 |
Totals | 41499 | 6795654 |
No co-occurrence statistics for GO:0033152 based on MANUAL annotations
The top 100 of 239 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
immunoglobulin V(D)J recombination
|
16,147.49 | 100.00 | 80 | 80 |
DNA-dependent protein kinase-DNA ligase 4 complex
|
5,733.53 | 28.99 | 49 | 138 |
DNA ligation involved in DNA repair
|
4,791.01 | 18.75 | 27 | 91 |
nonhomologous end joining complex
|
5,382.50 | 17.74 | 22 | 66 |
DNA ligase IV complex
|
3,245.33 | 16.87 | 41 | 204 |
pro-B cell differentiation
|
9,541.70 | 14.61 | 13 | 22 |
response to X-ray
|
2,094.81 | 9.96 | 24 | 185 |
T cell receptor V(D)J recombination
|
5,011.29 | 9.00 | 9 | 29 |
DN2 thymocyte differentiation
|
7,176.66 | 8.89 | 8 | 18 |
V(D)J recombination
|
2,430.80 | 8.81 | 14 | 93 |
Totals | 815 | 14200 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2157 (Archaea) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2 (Bacteria) |
2010-12-01 | Deleted | DEFINITION | The process by which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined. |
2010-12-01 | Added | DEFINITION | The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined. |
2010-03-11 | Deleted | SYNONYM | immunoglobulin V-D-J joining |
2010-03-11 | Deleted | DEFINITION | The process by which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin light chains the same process is used to join V and J gene segments directly. |
2010-03-11 | Added | DEFINITION | The process by which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined. |
2010-03-11 | Deleted | SYNONYM | immunoglobulin V-J joining |
Timestamp | Action | Category | Detail |
---|---|---|---|
2007-04-14 | Added | TERM | immunoglobulin V(D)J recombination |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-12-01 | Deleted | DEFINITION | The process by which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined. |
2010-12-01 | Added | DEFINITION | The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined. |
2010-03-11 | Deleted | SYNONYM | immunoglobulin V-D-J joining |
2010-03-11 | Deleted | DEFINITION | The process by which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin light chains the same process is used to join V and J gene segments directly. |
2010-03-11 | Added | DEFINITION | The process by which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined. |
2010-03-11 | Deleted | SYNONYM | immunoglobulin V-J joining |
2010-03-11 | Deleted | SYNONYM | immunoglobulin V-J recombination |
2010-03-11 | Deleted | SYNONYM | immunoglobulin V-D-J recombination |
2010-03-11 | Added | SYNONYM | immunoglobulin V-D-J recombination |
2010-03-11 | Added | SYNONYM | immunoglobulin V-J recombination |
2010-03-11 | Added | SYNONYM | immunoglobulin V-D-J joining |
2010-03-11 | Added | SYNONYM | immunoglobulin V-J joining |
2008-05-13 | Added | DEFINITION | The process by which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin light chains the same process is used to join V and J gene segments directly. |
2008-05-12 | Deleted | DEFINITION | The process by which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin light chains the same process is used to join V and J gene segments directly. |
2007-08-09 | Deleted | SYNONYM | immunoglobulin V-D-J recombination |
2007-08-09 | Added | SYNONYM | immunoglobulin V(D)J joining |
2007-08-09 | Deleted | SYNONYM | immunoglobulin V-J joining |
2007-08-09 | Deleted | SYNONYM | immunoglobulin V(D)J joining |
2007-08-09 | Deleted | SYNONYM | immunoglobulin V-D-J joining |
2007-08-09 | Deleted | SYNONYM | immunoglobulin V-J recombination |
2007-08-09 | Added | SYNONYM | immunoglobulin V-D-J joining |
2007-08-09 | Added | SYNONYM | immunoglobulin V-D-J recombination |
2007-08-09 | Added | SYNONYM | immunoglobulin V-J joining |
2007-08-09 | Added | SYNONYM | immunoglobulin V-J recombination |
2007-04-20 | Added | DEFINITION | The process by which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin light chains the same process is used to join V and J gene segments directly. |
2007-04-14 | Added | SYNONYM | immunoglobulin V-J joining |
2007-04-14 | Added | SYNONYM | immunoglobulin V(D)J joining |
2007-04-14 | Added | SYNONYM | immunoglobulin V-J recombination |
2007-04-14 | Added | SYNONYM | immunoglobulin V-D-J recombination |
2007-04-14 | Added | SYNONYM | immunoglobulin V-D-J joining |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016447 (somatic recombination of immunoglobulin gene segments) |
2008-04-01 | Updated | RELATION | is a GO:0033151 (V(D)J recombination) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2157 (Archaea) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2 (Bacteria) |
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