This term is obsolete.

GO:0033490 JSON

cholesterol biosynthetic process via lathosterol

Biological Process

Definition (GO:0033490 GONUTS page)

The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol.

224 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
cholesterol synthesis via lathosterol exact
cholesterol anabolism via lathosterol exact
cholesterol biosynthesis via lathosterol exact
cholesterol formation via lathosterol exact

Ancestor Chart

Ancestor chart for GO:0033490
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Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0033490 cholesterol biosynthetic process via lathosterol Never in Taxon 4895 Schizosaccharomyces
GO:0033490 cholesterol biosynthetic process via lathosterol Never in Taxon 4930 Saccharomyces

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A1D8PT92 237561 A0A1D8PT92_CANAL GO:0008202 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A7EKP7 665079 A7EKP7_SCLS1 GO:0008202 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P95028 83331 P95028_MYCTO GO:0008610 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16952959
NOT-qualified manual protein Q0UV92 321614 Q0UV92_PHANO GO:0008202 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein Q4WKE9 330879 Q4WKE9_ASPFU GO:0008202 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein Q5BGM7 227321 Q5BGM7_EMENI GO:0008202 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein Q6C017 284591 Q6C017_YARLI GO:0008202 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein Q7SGR1 367110 Q7SGR1_NEUCR GO:0008202 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-references

Database ID Description
MetaCyc PWY66-341

Cross-Ontology Relations

Relation Other Ontology ID Term
has_intermediate CHEBI CHEBI:17168 5alpha-cholest-7-en-3beta-ol
has_primary_output CHEBI CHEBI:16113 cholesterol

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0033490 based on ALL annotations
The top 64 of 64 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cholesterol biosynthetic process via lathosterol
941,733.25 100.00 207 207
delta7-sterol 5(6)-desaturase activity
590,073.40 37.22 99 158
positive regulation of ferroptosis
365,567.34 26.14 92 237
negative regulation of ferroptosis
115,815.64 10.84 99 805
C-5 sterol desaturase activity
80,432.73 5.17 24 281
7-dehydrocholesterol reductase activity
32,231.94 3.28 92 2,688
cholesterol-5,6-oxide hydrolase activity
289,764.06 1.85 4 13
cholesterol biosynthetic process via desmosterol
36,220.51 1.30 4 104
organic hydroxy compound biosynthetic process
9,669.16 1.01 91 8,863
brassinosteroid biosynthetic process
5,842.21 0.61 77 12,412
Totals 2460 112512922
No co-occurrence statistics for GO:0033490 based on MANUAL annotations
The top 42 of 42 co-occurring terms
Co-occurring Term PR S% #Together #Compared
cholesterol biosynthetic process via lathosterol
46,135.68 100.00 28 28
C-5 sterol desaturase activity
8,769.59 18.25 23 121
cholesterol biosynthetic process via desmosterol
36,908.54 13.79 4 5
delta7-sterol 5(6)-desaturase activity
46,135.68 10.71 3 3
cholesterol-5,6-oxide hydrolase activity
15,378.56 8.82 3 9
positive regulation of ferroptosis
7,097.80 5.13 2 13
negative regulation of ferroptosis
2,196.94 3.41 3 63
delta24-sterol reductase activity
15,378.56 3.33 1 3
7-dehydrocholesterol reductase activity
1,182.97 1.92 2 78
lung epithelial cell differentiation
981.61 1.35 1 47
Totals 141 542531

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4930 (Saccharomyces)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
2008-05-13 Added DEFINITION The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol.
2008-04-01 Updated RELATION is a GO:0006695 (cholesterol biosynthetic process)
2007-08-09 Added SYNONYM cholesterol formation via lathosterol
2007-08-09 Added SYNONYM cholesterol synthesis via lathosterol
2007-08-09 Added SYNONYM cholesterol biosynthesis via lathosterol
2007-08-09 Added SYNONYM cholesterol anabolism via lathosterol
2007-08-09 Deleted SYNONYM cholesterol synthesis via lathosterol
Timestamp Action Category Detail
2007-07-15 Added TERM cholesterol biosynthetic process via lathosterol
Timestamp Action Category Detail
2008-05-13 Added DEFINITION The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol.
2008-05-12 Deleted DEFINITION The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol.
2007-08-09 Added SYNONYM cholesterol formation via lathosterol
2007-08-09 Added SYNONYM cholesterol synthesis via lathosterol
2007-08-09 Added SYNONYM cholesterol biosynthesis via lathosterol
2007-08-09 Added SYNONYM cholesterol anabolism via lathosterol
2007-08-09 Deleted SYNONYM cholesterol synthesis via lathosterol
2007-08-09 Deleted SYNONYM cholesterol biosynthesis via lathosterol
2007-08-09 Deleted SYNONYM cholesterol anabolism via lathosterol
2007-08-09 Deleted SYNONYM cholesterol formation via lathosterol
2007-07-27 Added DEFINITION The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol.
2007-07-15 Added SYNONYM cholesterol synthesis via lathosterol
2007-07-15 Added SYNONYM cholesterol anabolism via lathosterol
2007-07-15 Added SYNONYM cholesterol biosynthesis via lathosterol
2007-07-15 Added SYNONYM cholesterol formation via lathosterol
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0006695 (cholesterol biosynthetic process)
Timestamp Action Category Detail
2007-07-19 Added XREF MetaCyc:PWY66-341
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4930 (Saccharomyces)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
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