This term is obsolete.

GO:0033573 JSON

high-affinity iron permease complex

Cellular Component

Definition (GO:0033573 GONUTS page)

A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. PMID:16522632 PMID:8599111

21,045 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
high affinity iron permease complex exact

Ancestor Chart

Ancestor chart for GO:0033573
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Ancestor chart

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 237631 BI1_USTMA GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016020 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A022QST3 4155 A0A022QST3_ERYGU GO:0005886 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A022S0M6 4155 A0A022S0M6_ERYGU GO:0005886 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A059AQE2 71139 A0A059AQE2_EUCGR GO:0005886 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A059B0U9 71139 A0A059B0U9_EUCGR GO:0005886 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-references

Database ID Description
InterPro IPR004923 Iron permease FTR1/Fip1/EfeU
InterPro IPR005217 Iron permease FTR1-like

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0033573 based on ALL annotations
The top 100 of 161 co-occurring terms
Co-occurring Term PR S% #Together #Compared
high-affinity iron permease complex
9,284.57 100.00 20,996 20,996
iron ion transmembrane transporter activity
4,938.44 48.53 17,784 33,435
ferrous iron transmembrane transporter activity
1,864.20 19.33 17,595 87,631
reductive iron assimilation
7,859.98 15.45 3,338 3,943
cellular response to iron ion starvation
6,792.21 14.62 3,243 4,433
iron ion transmembrane transport
1,008.41 10.65 17,786 163,758
ferroxidase activity
581.88 4.67 3,241 51,714
iron ion transport
90.76 0.93 3,293 336,853
hydroquinone:oxygen oxidoreductase activity
176.09 0.65 205 10,809
copper ion binding
52.41 0.55 3,235 573,134
Totals 144470 124399764
No co-occurrence statistics for GO:0033573 based on MANUAL annotations
The top 45 of 45 co-occurring terms
Co-occurring Term PR S% #Together #Compared
high-affinity iron permease complex
20,184.36 100.00 64 64
reductive iron assimilation
5,766.96 19.35 24 84
cellular response to iron ion starvation
4,587.35 16.78 25 110
ferrous iron transmembrane transporter activity
2,722.23 12.54 41 304
ferroxidase activity
1,934.33 8.19 23 240
iron ion transmembrane transport
1,566.33 7.50 44 567
arsenate ion transmembrane transport
5,766.96 2.90 2 7
iron ion import across cell outer membrane
5,766.96 2.90 2 7
high-affinity ferrous iron transmembrane transporter activity
10,092.18 1.54 1 2
high-affinity iron exporter complex
10,092.18 1.54 1 2
Totals 327 388546

Change Log

Timestamp Action Category Detail
2021-05-04 Deleted XREF IntAct:EBI-12592666
2019-09-18 Deleted RELATION is a GO:0005887 (integral component of plasma membrane)
2019-08-30 Deleted RELATION is a GO:1990204 (oxidoreductase complex)
2018-11-18 Deleted RELATION capable of part of GO:0098706 (iron ion import across cell outer membrane)
2018-08-20 Added RELATION capable of part of GO:0098706 (iron ion import across cell outer membrane)
2018-08-20 Deleted RELATION capable of part of GO:0015683 (ferric iron transmembrane transport)
2018-07-29 Added RELATION capable of part of GO:0015683 (ferric iron transmembrane transport)
2017-11-08 Deleted RELATION capable of part of GO:0015683 (ferric iron transmembrane transport)
2017-10-07 Added XREF IntAct:EBI-12592666
2017-09-22 Added RELATION is a GO:1990204 (oxidoreductase complex)
Timestamp Action Category Detail
2014-09-05 Updated TERM high-affinity iron permease complex
2007-08-05 Added TERM high affinity iron permease complex
Timestamp Action Category Detail
2014-09-05 Added SYNONYM high affinity iron permease complex
2014-09-05 Deleted DEFINITION A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell.
2014-09-05 Added DEFINITION A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
2008-05-13 Added DEFINITION A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell.
2008-05-12 Deleted DEFINITION A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell.
2007-10-25 Added DEFINITION A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell.
Timestamp Action Category Detail
2019-09-18 Deleted RELATION is a GO:0005887 (integral component of plasma membrane)
2019-08-30 Deleted RELATION is a GO:1990204 (oxidoreductase complex)
2018-11-18 Deleted RELATION capable of part of GO:0098706 (iron ion import across cell outer membrane)
2018-08-20 Added RELATION capable of part of GO:0098706 (iron ion import across cell outer membrane)
2018-08-20 Deleted RELATION capable of part of GO:0015683 (ferric iron transmembrane transport)
2018-07-29 Added RELATION capable of part of GO:0015683 (ferric iron transmembrane transport)
2017-11-08 Deleted RELATION capable of part of GO:0015683 (ferric iron transmembrane transport)
2017-09-22 Added RELATION is a GO:1990204 (oxidoreductase complex)
2017-05-22 Added RELATION capable of part of GO:0015683 (ferric iron transmembrane transport)
2017-04-06 Deleted RELATION capable of part of GO:0015683 (ferric iron transmembrane transport)
2017-01-31 Added RELATION capable of GO:0008199 (ferric iron binding)
2017-01-31 Added RELATION capable of part of GO:0015683 (ferric iron transmembrane transport)
2017-01-31 Added RELATION is a GO:1902495 (transmembrane transporter complex)
2017-01-31 Added RELATION capable of GO:0008198 (ferrous iron binding)
2017-01-31 Added RELATION is a GO:1905862 (ferroxidase complex)
2017-01-31 Added RELATION is a GO:0005887 (integral component of plasma membrane)
2017-01-31 Added RELATION capable of GO:0015092 (high-affinity ferric iron transmembrane transporter activity)
2015-06-25 Deleted RELATION is a GO:0044459 (obsolete plasma membrane part)
2015-06-25 Deleted RELATION is a GO:0043234 (protein complex)
2015-05-11 Added RELATION is a GO:0098797 (plasma membrane protein complex)
2008-04-01 Updated RELATION is a GO:0044459 (obsolete plasma membrane part)
2008-04-01 Updated RELATION is a GO:0043234 (protein complex)
Timestamp Action Category Detail
2021-05-04 Deleted XREF IntAct:EBI-12592666
2017-10-07 Added XREF IntAct:EBI-12592666
Timestamp Action Category Detail
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