GO:0033739
JSON
preQ1 synthase activity
Molecular Function
Definition (GO:0033739 GONUTS page)
Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP+ = 7-cyano-7-deazaguanine + 3 H+ + 2 NADPH.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
QueF | related |
YkvM | related |
preQ0 oxidoreductase activity | related |
preQ0 reductase activity | related |
7-cyano-7-deazaguanine reductase activity | related |
queuine synthase activity | related |
queuine:NADP+ oxidoreductase activity | related |
7-aminomethyl-7-carbaguanine:NADP+ oxidoreductase activity | exact |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 237631 | BI1_USTMA | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 | |
NOT-qualified manual | protein | A7EKP7 | 665079 | A7EKP7_SCLS1 | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 1.7.1.13 | |
InterPro | IPR029500 | NADPH-dependent 7-cyano-7-deazaguanine reductase QueF |
KEGG_REACTION | R07605 | |
MetaCyc | RXN0-4022 | |
RHEA | 13409 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:58349 | NADP(3-) |
has_participant | CHEBI | CHEBI:58703 | 7-ammoniomethyl-7-deazaguanine |
has_participant | CHEBI | CHEBI:57783 | NADPH(4-) |
has_participant | CHEBI | CHEBI:45075 | 7-cyano-7-deazaguanine |
has_participant | CHEBI | CHEBI:15378 | hydron |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0033739 based on ALL annotations
The top 69 of 69 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
preQ1 synthase activity
|
8,713.52 | 100.00 | 22,372 | 22,372 |
queuosine biosynthetic process
|
973.11 | 11.16 | 22,264 | 199,359 |
tRNA modification
|
274.10 | 3.14 | 20,459 | 650,376 |
oxidoreductase activity
|
15.45 | 0.18 | 21,114 | 11,906,003 |
cytoplasm
|
7.42 | 0.09 | 21,540 | 25,285,876 |
oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor
|
18.18 | 0.03 | 9 | 4,313 |
GTP cyclohydrolase I activity
|
1.77 | 0.01 | 11 | 54,173 |
D-ribulokinase activity
|
1.48 | 0.01 | 3 | 17,623 |
D-xylulokinase activity
|
0.99 | 0.01 | 3 | 26,415 |
xylulose metabolic process
|
0.90 | 0.01 | 3 | 29,138 |
Totals | 108286 | 284479698 |
No co-occurrence statistics for GO:0033739 based on MANUAL annotations
The top 3 of 3 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
preQ1 synthase activity
|
1,291,799.00 | 100.00 | 1 | 1 |
queuosine biosynthetic process
|
15,020.92 | 1.16 | 1 | 86 |
cytosol
|
15.34 | 0.00 | 1 | 84,217 |
Totals | 3 | 84304 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-09-01 | Added | DEFINITION | Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP+ = 7-cyano-7-deazaguanine + 3 H+ + 2 NADPH. |
2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH. |
2022-05-26 | Deleted | RELATION | is a GO:0016657 (obsolete oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor) |
2022-05-26 | Added | RELATION | is a GO:0046857 (oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor) |
2020-10-08 | Deleted | SYNONYM | 7-cyano-7-deazaguanine reductase activity |
2020-10-08 | Deleted | SYNONYM | preQ0 oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | preQ0 reductase activity |
2020-10-08 | Added | SYNONYM | preQ0 oxidoreductase activity |
2020-10-08 | Added | SYNONYM | 7-cyano-7-deazaguanine reductase activity |
2020-10-08 | Added | SYNONYM | preQ0 reductase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-05-27 | Updated | TERM | preQ1 synthase activity |
2007-11-08 | Added | TERM | queuine synthase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-09-01 | Added | DEFINITION | Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP+ = 7-cyano-7-deazaguanine + 3 H+ + 2 NADPH. |
2022-09-01 | Deleted | DEFINITION | Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH. |
2020-10-08 | Deleted | SYNONYM | 7-cyano-7-deazaguanine reductase activity |
2020-10-08 | Deleted | SYNONYM | preQ0 oxidoreductase activity |
2020-10-08 | Deleted | SYNONYM | preQ0 reductase activity |
2020-10-08 | Added | SYNONYM | preQ0 oxidoreductase activity |
2020-10-08 | Added | SYNONYM | 7-cyano-7-deazaguanine reductase activity |
2020-10-08 | Added | SYNONYM | preQ0 reductase activity |
2011-05-27 | Added | SYNONYM | queuine:NADP+ oxidoreductase activity |
2011-05-27 | Added | SYNONYM | queuine synthase activity |
2011-05-27 | Deleted | SYNONYM | queuine:NADP+ oxidoreductase activity |
2010-10-11 | Added | DEFINITION | Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH. |
2010-10-11 | Deleted | DEFINITION | Catalysis of the reaction: queuine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH + 2 H+. |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: queuine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH + 2 H+. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: queuine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH + 2 H+. |
2007-12-06 | Deleted | SYNONYM | queuine synthase activity |
2007-11-27 | Added | DEFINITION | Catalysis of the reaction: queuine + 2 NADP+ = 7-cyano-7-carbaguanine + 2 NADPH + 2 H+. |
2007-11-08 | Added | SYNONYM | preQ0 oxidoreductase activity |
2007-11-08 | Added | SYNONYM | YkvM |
2007-11-08 | Added | SYNONYM | QueF |
2007-11-08 | Added | SYNONYM | 7-cyano-7-deazaguanine reductase activity |
2007-11-08 | Added | SYNONYM | 7-aminomethyl-7-carbaguanine:NADP+ oxidoreductase activity |
2007-11-08 | Added | SYNONYM | queuine synthase activity |
2007-11-08 | Added | SYNONYM | queuine:NADP+ oxidoreductase activity |
2007-11-08 | Added | SYNONYM | preQ0 reductase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-05-26 | Deleted | RELATION | is a GO:0016657 (obsolete oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor) |
2022-05-26 | Added | RELATION | is a GO:0046857 (oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor) |
2008-04-01 | Updated | RELATION | is a GO:0016646 (oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor) |
2008-04-01 | Updated | RELATION | is a GO:0016657 (obsolete oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2019-06-20 | Deleted | XREF | KEGG:R07605 |
2019-06-20 | Added | XREF | KEGG_REACTION:R07605 |
2018-07-13 | Added | XREF | RHEA:13409 |
2018-07-13 | Deleted | XREF | RHEA:13412 |
2010-10-11 | Added | XREF | RHEA:13412 |
2010-10-11 | Added | XREF | MetaCyc:RXN0-4022 |
2010-10-11 | Added | XREF | KEGG:R07605 |
2007-11-08 | Added | XREF | EC:1.7.1.13 |
Timestamp | Action | Category | Detail |
---|
Not found :(
Sorry, but the Term you were trying to view does not exist.
Reported error:
It looks like this may have been caused by:
- a mistyped URL
- an out-of-date link