GO:0033764
JSON
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Molecular Function
Definition (GO:0033764 GONUTS page)
Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0033764
Child Term | Relationship to GO:0033764 |
---|---|
estradiol 17-alpha-dehydrogenase [NAD(P)+] activity
|
is_a |
3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase (NAD+) activity
|
is_a |
11-beta-hydroxysteroid dehydrogenase [NAD(P)+] activity
|
is_a |
cholate 12-alpha dehydrogenase activity
|
is_a |
5-alpha-androstane-3beta,17beta-diol dehydrogenase (NADP+) activity
|
is_a |
3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity
|
is_a |
16-alpha-hydroxysteroid dehydrogenase (NADP+) activity
|
is_a |
ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity
|
is_a |
17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase [NAD(P)+] activity
|
is_a |
isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | O63264 | 4957 | ZBI1_ZYGBI | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03879 | 559292 | MBI4_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03880 | 162425 | ANI1_EMEND | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | P03882 | 559292 | SCE1_YEAST | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q0H8X2 | 237631 | BI1_USTMA | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
IEA Review | protein | Q35127 | 367110 | MBI1_NEUCR | GO:0016491 | Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012. | |
NOT-qualified manual | protein | A0A1D8PT92 | 237561 | A0A1D8PT92_CANAL | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1S4KZV0 | 6945 | A0A1S4KZV0_IXOSC | GO:0016616 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0MTA1 | 7955 | APEX1_DANRE | GO:0016491 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163 | |
NOT-qualified manual | protein | A5PJF6 | 9913 | HSDL1_BOVIN | GO:0016229 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 |
Cross-references
Database | ID | Description |
---|---|---|
Reactome | R-HSA-9758682 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0033764 based on ALL annotations
The top 74 of 74 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
3,248,979.80 | 100.00 | 60 | 60 |
multicellular organismal response to stress
|
154,244.50 | 4.69 | 47 | 990 |
androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity
|
143,866.27 | 4.38 | 48 | 1,084 |
lithocholic acid binding
|
196,907.88 | 3.92 | 6 | 99 |
17-beta-ketosteroid reductase (NADPH) activity
|
196,907.88 | 3.92 | 6 | 99 |
bile acid catabolic process
|
209,611.61 | 2.25 | 2 | 31 |
androsterone dehydrogenase [NAD(P)+] activity
|
77,356.66 | 2.10 | 9 | 378 |
3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase activity
|
106,523.93 | 1.68 | 2 | 61 |
11-deoxycorticosterone reductase activity
|
3,248,979.80 | 1.67 | 1 | 1 |
3beta-hydroxy-5beta-steroid dehydrogenase activity
|
541,496.70 | 1.54 | 1 | 6 |
Totals | 482 | 111487271 |
No co-occurrence statistics for GO:0033764 based on MANUAL annotations
The top 58 of 58 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
|
129,179.90 | 100.00 | 10 | 10 |
lithocholic acid binding
|
51,671.96 | 15.38 | 2 | 5 |
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
|
28,706.65 | 11.76 | 2 | 9 |
3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase activity
|
129,179.90 | 10.00 | 1 | 1 |
response to bile acid
|
16,147.49 | 8.33 | 2 | 16 |
17-beta-ketosteroid reductase (NADPH) activity
|
16,147.49 | 8.33 | 2 | 16 |
androsterone dehydrogenase [NAD(P)+] activity
|
10,417.73 | 7.46 | 5 | 62 |
cellular response to jasmonic acid stimulus
|
12,302.85 | 6.90 | 2 | 21 |
androsterone dehydrogenase (B-specific) activity
|
18,454.27 | 6.25 | 1 | 7 |
5-alpha-androstane-3beta,17beta-diol dehydrogenase (NADP+) activity
|
10,764.99 | 6.25 | 2 | 24 |
Totals | 105 | 369208 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-04-02 | Added | XREF | Reactome:R-HSA-9758682 |
2018-02-11 | Updated | TERM | steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
2018-01-31 | Updated | TERM | steroid dehydrogenase activity, , acting on the CH-OH group of donors, NAD or NADP as acceptor. |
2018-01-31 | Deleted | XREF | EC:1.1.1 |
2016-10-03 | Added | XREF | EC:1.1.1 |
2016-10-03 | Deleted | XREF | EC:1.1.1.- |
2008-05-13 | Added | DEFINITION | Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. |
2008-05-12 | Deleted | DEFINITION | Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. |
2008-04-01 | Updated | RELATION | is a GO:0016229 (steroid dehydrogenase activity) |
2008-04-01 | Updated | RELATION | is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-02-11 | Updated | TERM | steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
2018-01-31 | Updated | TERM | steroid dehydrogenase activity, , acting on the CH-OH group of donors, NAD or NADP as acceptor. |
2007-12-01 | Added | TERM | steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. |
2008-05-12 | Deleted | DEFINITION | Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. |
2007-12-27 | Added | DEFINITION | Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016229 (steroid dehydrogenase activity) |
2008-04-01 | Updated | RELATION | is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-04-02 | Added | XREF | Reactome:R-HSA-9758682 |
2018-01-31 | Deleted | XREF | EC:1.1.1 |
2016-10-03 | Added | XREF | EC:1.1.1 |
2016-10-03 | Deleted | XREF | EC:1.1.1.- |
2007-12-01 | Added | XREF | EC:1.1.1.- |
Timestamp | Action | Category | Detail |
---|
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