This term is obsolete.

GO:0033764 JSON

steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Molecular Function

Definition (GO:0033764 GONUTS page)

Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.

28,961 annotations

Ancestor Chart

Ancestor chart for GO:0033764
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0033764

Child Term Relationship to
GO:0033764
estradiol 17-alpha-dehydrogenase [NAD(P)+] activity
is_a
3-beta-hydroxysteroid dehydrogenase/C4-decarboxylase (NAD+) activity
is_a
11-beta-hydroxysteroid dehydrogenase [NAD(P)+] activity
is_a
cholate 12-alpha dehydrogenase activity
is_a
5-alpha-androstane-3beta,17beta-diol dehydrogenase (NADP+) activity
is_a
3-beta-hydroxy-delta5-steroid dehydrogenase (NAD+) activity
is_a
16-alpha-hydroxysteroid dehydrogenase (NADP+) activity
is_a
ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity
is_a
17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase [NAD(P)+] activity
is_a
isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein O63264 4957 ZBI1_ZYGBI GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03879 559292 MBI4_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03880 162425 ANI1_EMEND GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein P03882 559292 SCE1_YEAST GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q0H8X2 237631 BI1_USTMA GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
IEA Review protein Q35127 367110 MBI1_NEUCR GO:0016491 Proteins appear to be intron-encoded endonucleases that hit InterPro cytochrome b/b6 (IPR016175) and Di-haem cytochrome (IPR016174) entries. Communicated by InterPro 29-05-2012.
NOT-qualified manual protein A0A1D8PT92 237561 A0A1D8PT92_CANAL GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1S4KZV0 6945 A0A1S4KZV0_IXOSC GO:0016616 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0MTA1 7955 APEX1_DANRE GO:0016491 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:18579163
NOT-qualified manual protein A5PJF6 9913 HSDL1_BOVIN GO:0016229 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024

Cross-references

Database ID Description
Reactome R-HSA-9758682

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0033764 based on ALL annotations
The top 74 of 74 co-occurring terms
Co-occurring Term PR S% #Together #Compared
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
3,248,979.80 100.00 60 60
multicellular organismal response to stress
154,244.50 4.69 47 990
androstan-3-alpha,17-beta-diol dehydrogenase (NAD+) activity
143,866.27 4.38 48 1,084
lithocholic acid binding
196,907.88 3.92 6 99
17-beta-ketosteroid reductase (NADPH) activity
196,907.88 3.92 6 99
bile acid catabolic process
209,611.61 2.25 2 31
androsterone dehydrogenase [NAD(P)+] activity
77,356.66 2.10 9 378
3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase activity
106,523.93 1.68 2 61
11-deoxycorticosterone reductase activity
3,248,979.80 1.67 1 1
3beta-hydroxy-5beta-steroid dehydrogenase activity
541,496.70 1.54 1 6
Totals 482 111487271
No co-occurrence statistics for GO:0033764 based on MANUAL annotations
The top 58 of 58 co-occurring terms
Co-occurring Term PR S% #Together #Compared
steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
129,179.90 100.00 10 10
lithocholic acid binding
51,671.96 15.38 2 5
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
28,706.65 11.76 2 9
3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase activity
129,179.90 10.00 1 1
response to bile acid
16,147.49 8.33 2 16
17-beta-ketosteroid reductase (NADPH) activity
16,147.49 8.33 2 16
androsterone dehydrogenase [NAD(P)+] activity
10,417.73 7.46 5 62
cellular response to jasmonic acid stimulus
12,302.85 6.90 2 21
androsterone dehydrogenase (B-specific) activity
18,454.27 6.25 1 7
5-alpha-androstane-3beta,17beta-diol dehydrogenase (NADP+) activity
10,764.99 6.25 2 24
Totals 105 369208

Change Log

Timestamp Action Category Detail
2023-04-02 Added XREF Reactome:R-HSA-9758682
2018-02-11 Updated TERM steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
2018-01-31 Updated TERM steroid dehydrogenase activity, , acting on the CH-OH group of donors, NAD or NADP as acceptor.
2018-01-31 Deleted XREF EC:1.1.1
2016-10-03 Added XREF EC:1.1.1
2016-10-03 Deleted XREF EC:1.1.1.-
2008-05-13 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.
2008-05-12 Deleted DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.
2008-04-01 Updated RELATION is a GO:0016229 (steroid dehydrogenase activity)
2008-04-01 Updated RELATION is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Timestamp Action Category Detail
2018-02-11 Updated TERM steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
2018-01-31 Updated TERM steroid dehydrogenase activity, , acting on the CH-OH group of donors, NAD or NADP as acceptor.
2007-12-01 Added TERM steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.
2008-05-12 Deleted DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.
2007-12-27 Added DEFINITION Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016229 (steroid dehydrogenase activity)
2008-04-01 Updated RELATION is a GO:0016616 (oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)
Timestamp Action Category Detail
2023-04-02 Added XREF Reactome:R-HSA-9758682
2018-01-31 Deleted XREF EC:1.1.1
2016-10-03 Added XREF EC:1.1.1
2016-10-03 Deleted XREF EC:1.1.1.-
2007-12-01 Added XREF EC:1.1.1.-
Timestamp Action Category Detail
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