This term is obsolete.

GO:0033814 JSON

propanoyl-CoA C-acyltransferase activity

Molecular Function

Definition (GO:0033814 GONUTS page)

Catalysis of the reaction: choloyl-CoA + propanoyl-CoA = 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + CoA.

1,232 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity related
sterol carrier protein-X related
sterol carrier protein-chi related
PTE-2 related
SCP-X related
SCPchi related
peroxisomal thiolase 2 activity narrow

Ancestor Chart

Ancestor chart for GO:0033814
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein P53817 10116 PLAT3_RAT GO:0016746 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7KV84 7227 Q7KV84_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7YTX2 7227 Q7YTX2_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I939 7227 Q8I939_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593

Cross-references

Database ID Description
EC 2.3.1.176
MetaCyc 2.3.1.176-RXN
RHEA 16865

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:57392 propionyl-CoA(4-)
has_participant CHEBI CHEBI:57287 coenzyme A(4-)
has_participant CHEBI CHEBI:57373 choloyl-CoA(4-)
has_participant CHEBI CHEBI:58507 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA(4-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0033814 based on ALL annotations
The top 95 of 95 co-occurring terms
Co-occurring Term PR S% #Together #Compared
propanoyl-CoA C-acyltransferase activity
158,358.08 100.00 1,231 1,231
propionyl-CoA C2-trimethyltridecanoyltransferase activity
158,358.08 99.84 1,229 1,229
acetyl-CoA C-myristoyltransferase activity
156,394.95 76.91 956 968
positive regulation of intracellular cholesterol transport
92,523.82 4.10 52 89
lipid hydroperoxide transport
43,340.10 3.80 52 190
oleic acid binding
35,735.67 3.63 51 226
long-chain fatty acyl-CoA binding
22,686.13 3.32 51 356
acetyl-CoA C-acyltransferase activity
2,452.07 1.54 958 61,869
lipid transport
491.13 0.31 1,006 324,372
peroxisome
423.64 0.27 1,017 380,161
Totals 12398 189547582
No co-occurrence statistics for GO:0033814 based on MANUAL annotations
The top 15 of 15 co-occurring terms
Co-occurring Term PR S% #Together #Compared
propanoyl-CoA C-acyltransferase activity
1,291,799.00 100.00 1 1
dauer exit
107,649.92 8.33 1 12
positive regulation of nematode larval development
99,369.16 7.69 1 13
dauer entry
75,988.18 5.88 1 17
ascaroside biosynthetic process
71,766.61 5.56 1 18
pheromone biosynthetic process
58,718.13 4.55 1 22
positive regulation of developmental growth
33,994.71 2.63 1 38
negative regulation of lipid storage
22,663.14 1.75 1 57
regulation of chemotaxis
15,948.14 1.23 1 81
olfactory learning
11,233.03 0.87 1 115
Totals 15 6110

Change Log

Timestamp Action Category Detail
2024-09-02 Added DEFINITION Catalysis of the reaction: choloyl-CoA + propanoyl-CoA = 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + CoA.
2024-09-02 Deleted DEFINITION Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.
2020-10-08 Deleted SYNONYM 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity
2020-10-08 Added SYNONYM 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity
2018-07-13 Added XREF RHEA:16865
2018-07-13 Deleted XREF RHEA:16868
2011-09-16 Added XREF RHEA:16868
2009-05-21 Added XREF MetaCyc:2.3.1.176-RXN
2008-05-13 Added DEFINITION Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.
Timestamp Action Category Detail
2007-12-06 Added TERM propanoyl-CoA C-acyltransferase activity
Timestamp Action Category Detail
2024-09-02 Added DEFINITION Catalysis of the reaction: choloyl-CoA + propanoyl-CoA = 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + CoA.
2024-09-02 Deleted DEFINITION Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.
2020-10-08 Deleted SYNONYM 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity
2020-10-08 Added SYNONYM 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.
2007-12-27 Added DEFINITION Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.
2007-12-06 Added SYNONYM SCP-X
2007-12-06 Added SYNONYM SCPchi
2007-12-06 Added SYNONYM sterol carrier protein-X
2007-12-06 Added SYNONYM 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity
2007-12-06 Added SYNONYM peroxisomal thiolase 2 activity
2007-12-06 Added SYNONYM PTE-2
2007-12-06 Added SYNONYM sterol carrier protein-chi
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016408 (C-acyltransferase activity)
Timestamp Action Category Detail
2018-07-13 Added XREF RHEA:16865
2018-07-13 Deleted XREF RHEA:16868
2011-09-16 Added XREF RHEA:16868
2009-05-21 Added XREF MetaCyc:2.3.1.176-RXN
2007-12-06 Added XREF EC:2.3.1.176
Timestamp Action Category Detail
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