GO:0033814
JSON
propanoyl-CoA C-acyltransferase activity
Molecular Function
Definition (GO:0033814 GONUTS page)
Catalysis of the reaction: choloyl-CoA + propanoyl-CoA = 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + CoA.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity | related |
sterol carrier protein-X | related |
sterol carrier protein-chi | related |
PTE-2 | related |
SCP-X | related |
SCPchi | related |
peroxisomal thiolase 2 activity | narrow |
Ancestor Chart
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | P53817 | 10116 | PLAT3_RAT | GO:0016746 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q0E8K5 | 7227 | Q0E8K5_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7JY99 | 7227 | Q7JY99_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7KV84 | 7227 | Q7KV84_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7YTX2 | 7227 | Q7YTX2_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I939 | 7227 | Q8I939_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.3.1.176 | |
MetaCyc | 2.3.1.176-RXN | |
RHEA | 16865 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:57392 | propionyl-CoA(4-) |
has_participant | CHEBI | CHEBI:57287 | coenzyme A(4-) |
has_participant | CHEBI | CHEBI:57373 | choloyl-CoA(4-) |
has_participant | CHEBI | CHEBI:58507 | 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA(4-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0033814 based on ALL annotations
The top 95 of 95 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
propanoyl-CoA C-acyltransferase activity
|
158,358.08 | 100.00 | 1,231 | 1,231 |
propionyl-CoA C2-trimethyltridecanoyltransferase activity
|
158,358.08 | 99.84 | 1,229 | 1,229 |
acetyl-CoA C-myristoyltransferase activity
|
156,394.95 | 76.91 | 956 | 968 |
positive regulation of intracellular cholesterol transport
|
92,523.82 | 4.10 | 52 | 89 |
lipid hydroperoxide transport
|
43,340.10 | 3.80 | 52 | 190 |
oleic acid binding
|
35,735.67 | 3.63 | 51 | 226 |
long-chain fatty acyl-CoA binding
|
22,686.13 | 3.32 | 51 | 356 |
acetyl-CoA C-acyltransferase activity
|
2,452.07 | 1.54 | 958 | 61,869 |
lipid transport
|
491.13 | 0.31 | 1,006 | 324,372 |
peroxisome
|
423.64 | 0.27 | 1,017 | 380,161 |
Totals | 12398 | 189547582 |
No co-occurrence statistics for GO:0033814 based on MANUAL annotations
The top 15 of 15 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
propanoyl-CoA C-acyltransferase activity
|
1,291,799.00 | 100.00 | 1 | 1 |
dauer exit
|
107,649.92 | 8.33 | 1 | 12 |
positive regulation of nematode larval development
|
99,369.16 | 7.69 | 1 | 13 |
dauer entry
|
75,988.18 | 5.88 | 1 | 17 |
ascaroside biosynthetic process
|
71,766.61 | 5.56 | 1 | 18 |
pheromone biosynthetic process
|
58,718.13 | 4.55 | 1 | 22 |
positive regulation of developmental growth
|
33,994.71 | 2.63 | 1 | 38 |
negative regulation of lipid storage
|
22,663.14 | 1.75 | 1 | 57 |
regulation of chemotaxis
|
15,948.14 | 1.23 | 1 | 81 |
olfactory learning
|
11,233.03 | 0.87 | 1 | 115 |
Totals | 15 | 6110 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-02 | Added | DEFINITION | Catalysis of the reaction: choloyl-CoA + propanoyl-CoA = 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + CoA. |
2024-09-02 | Deleted | DEFINITION | Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA. |
2020-10-08 | Deleted | SYNONYM | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity |
2020-10-08 | Added | SYNONYM | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity |
2018-07-13 | Added | XREF | RHEA:16865 |
2018-07-13 | Deleted | XREF | RHEA:16868 |
2011-09-16 | Added | XREF | RHEA:16868 |
2009-05-21 | Added | XREF | MetaCyc:2.3.1.176-RXN |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2007-12-06 | Added | TERM | propanoyl-CoA C-acyltransferase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-02 | Added | DEFINITION | Catalysis of the reaction: choloyl-CoA + propanoyl-CoA = 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + CoA. |
2024-09-02 | Deleted | DEFINITION | Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA. |
2020-10-08 | Deleted | SYNONYM | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity |
2020-10-08 | Added | SYNONYM | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity |
2008-05-13 | Added | DEFINITION | Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA. |
2007-12-27 | Added | DEFINITION | Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA. |
2007-12-06 | Added | SYNONYM | SCP-X |
2007-12-06 | Added | SYNONYM | SCPchi |
2007-12-06 | Added | SYNONYM | sterol carrier protein-X |
2007-12-06 | Added | SYNONYM | 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity |
2007-12-06 | Added | SYNONYM | peroxisomal thiolase 2 activity |
2007-12-06 | Added | SYNONYM | PTE-2 |
2007-12-06 | Added | SYNONYM | sterol carrier protein-chi |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016408 (C-acyltransferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2018-07-13 | Added | XREF | RHEA:16865 |
2018-07-13 | Deleted | XREF | RHEA:16868 |
2011-09-16 | Added | XREF | RHEA:16868 |
2009-05-21 | Added | XREF | MetaCyc:2.3.1.176-RXN |
2007-12-06 | Added | XREF | EC:2.3.1.176 |
Timestamp | Action | Category | Detail |
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