This term is obsolete.

GO:0033814 JSON

propanoyl-CoA C-acyltransferase activity

Molecular Function

Definition (GO:0033814 GONUTS page)

Catalysis of the reaction: choloyl-CoA + propanoyl-CoA = 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + CoA.

1,226 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
PTE-2 related
3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity related
sterol carrier protein-X related
peroxisomal thiolase 2 activity narrow
sterol carrier protein-chi related
SCPchi related
SCP-X related

Ancestor Chart

Ancestor chart for GO:0033814
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q9VNA3 7227 Q9VNA3_DROME GO:0016740 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein P53817 10116 PLAT3_RAT GO:0016746 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein Q0E8K5 7227 Q0E8K5_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7JY99 7227 Q7JY99_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7KV84 7227 Q7KV84_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7YTX2 7227 Q7YTX2_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593
NOT-qualified manual protein Q8I939 7227 Q8I939_DROME GO:0016740 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593

Cross-references

Database ID Description
EC 2.3.1.176
MetaCyc 2.3.1.176-RXN
RHEA 16865

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:57287 coenzyme A(4-)
has_participant CHEBI CHEBI:57373 choloyl-CoA(4-)
has_participant CHEBI CHEBI:58507 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA(4-)
has_participant CHEBI CHEBI:57392 propionyl-CoA(4-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0033814 based on ALL annotations
The top 93 of 93 co-occurring terms
Co-occurring Term PR S% #Together #Compared
propanoyl-CoA C-acyltransferase activity
161,759.08 100.00 1,225 1,225
propionyl-CoA C2-trimethyltridecanoyltransferase activity
161,759.08 99.76 1,222 1,222
acetyl-CoA C-myristoyltransferase activity
159,739.19 76.72 949 961
positive regulation of intracellular cholesterol transport
94,510.91 4.12 52 89
lipid hydroperoxide transport
44,270.90 3.82 52 190
oleic acid binding
36,665.39 3.65 51 225
long-chain fatty acyl-CoA binding
23,912.21 3.36 51 345
acetyl-CoA C-acyltransferase activity
1,379.54 0.85 1,003 117,608
peroxisome
510.73 0.32 856 271,113
dauer exit
12,940.73 0.31 4 50
Totals 12326 192022231
No co-occurrence statistics for GO:0033814 based on MANUAL annotations
The top 15 of 15 co-occurring terms
Co-occurring Term PR S% #Together #Compared
propanoyl-CoA C-acyltransferase activity
1,411,533.00 100.00 1 1
dauer exit
117,627.75 8.33 1 12
positive regulation of nematode larval development
108,579.45 7.69 1 13
dauer entry
83,031.35 5.88 1 17
pheromone biosynthetic process
64,160.59 4.55 1 22
ascaroside biosynthetic process
50,411.90 3.57 1 28
positive regulation of developmental growth
39,209.25 2.78 1 36
negative regulation of lipid storage
25,205.95 1.79 1 56
regulation of chemotaxis
17,426.33 1.23 1 81
olfactory learning
12,381.87 0.88 1 114
Totals 15 6599

Change Log

Timestamp Action Category Detail
2024-09-02 Added DEFINITION Catalysis of the reaction: choloyl-CoA + propanoyl-CoA = 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + CoA.
2024-09-02 Deleted DEFINITION Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.
2020-10-08 Deleted SYNONYM 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity
2020-10-08 Added SYNONYM 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity
2018-07-13 Added XREF RHEA:16865
2018-07-13 Deleted XREF RHEA:16868
2011-09-16 Added XREF RHEA:16868
2009-05-21 Added XREF MetaCyc:2.3.1.176-RXN
2008-05-13 Added DEFINITION Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.
Timestamp Action Category Detail
2007-12-06 Added TERM propanoyl-CoA C-acyltransferase activity
Timestamp Action Category Detail
2024-09-02 Added DEFINITION Catalysis of the reaction: choloyl-CoA + propanoyl-CoA = 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestan-26-oyl-CoA + CoA.
2024-09-02 Deleted DEFINITION Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.
2020-10-08 Deleted SYNONYM 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity
2020-10-08 Added SYNONYM 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.
2007-12-27 Added DEFINITION Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.
2007-12-06 Added SYNONYM sterol carrier protein-chi
2007-12-06 Added SYNONYM sterol carrier protein-X
2007-12-06 Added SYNONYM peroxisomal thiolase 2 activity
2007-12-06 Added SYNONYM SCPchi
2007-12-06 Added SYNONYM SCP-X
2007-12-06 Added SYNONYM PTE-2
2007-12-06 Added SYNONYM 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA:propanoyl-CoA C-acyltransferase activity
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016408 (C-acyltransferase activity)
Timestamp Action Category Detail
2018-07-13 Added XREF RHEA:16865
2018-07-13 Deleted XREF RHEA:16868
2011-09-16 Added XREF RHEA:16868
2009-05-21 Added XREF MetaCyc:2.3.1.176-RXN
2007-12-06 Added XREF EC:2.3.1.176
Timestamp Action Category Detail
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