This term is obsolete.

GO:0034005 JSON

germacrene-A synthase activity

Molecular Function

Definition (GO:0034005 GONUTS page)

Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate.

80 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
(+)-germacrene A synthase activity related
2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (germacrene-A-forming) activity related
germacrene A synthase activity related
GAS related
(+)-(10R)-germacrene A synthase activity related
2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(+)-germacrene-A-forming] activity related

Ancestor Chart

Ancestor chart for GO:0034005
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Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
EC 4.2.3.23
KEGG_REACTION R07649
MetaCyc RXN-11527
RHEA 12516

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:33019 diphosphate(3-)
has_participant CHEBI CHEBI:41595 (+)-germacrene A
has_participant CHEBI CHEBI:175763 2-trans,6-trans-farnesyl diphosphate(3-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0034005 based on ALL annotations
The top 21 of 21 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0034005
germacrene-A synthase activity
2,642,064.80 100.00 75 75
GO:0102889
beta-elemene synthase activity
1,981,548.60 3.95 3 4
GO:0006720
isoprenoid metabolic process
37,931.79 1.42 49 3,413
GO:0046246
terpene biosynthetic process
31,679.44 1.14 15 1,251
GO:0010334
sesquiterpene synthase activity
56,214.15 0.83 1 47
GO:0016102
diterpenoid biosynthetic process
12,258.10 0.46 69 14,872
GO:0051762
sesquiterpene biosynthetic process
9,691.21 0.36 8 2,181
GO:0010333
terpene synthase activity
5,478.13 0.21 75 36,172
GO:0016838
carbon-oxygen lyase activity, acting on phosphates
2,195.62 0.08 6 7,220
GO:0010597
green leaf volatile biosynthetic process
1,230.58 0.05 3 6,441
Totals 557 136219340
No co-occurrence statistics for GO:0034005 based on MANUAL annotations
The top 7 of 7 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0034005
germacrene-A synthase activity
156,837.00 100.00 9 9
GO:0102889
beta-elemene synthase activity
117,627.76 30.00 3 4
GO:0016829
lyase activity
6,032.19 3.57 3 78
GO:0051762
sesquiterpene biosynthetic process
4,945.31 3.13 7 222
GO:0010597
green leaf volatile biosynthetic process
4,901.16 2.94 3 96
GO:0045338
farnesyl diphosphate metabolic process
2,163.27 1.32 2 145
GO:0010333
terpene synthase activity
998.96 0.63 3 471
Totals 30 1025

Change Log

Timestamp Action Category Detail
2023-08-11 Deleted XREF MetaCyc:4.2.3.23-RXN
2023-08-11 Added XREF MetaCyc:RXN-11527
2020-10-08 Deleted SYNONYM 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(+)-germacrene-A-forming] activity
2020-10-08 Added SYNONYM 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (germacrene-A-forming) activity
2020-10-08 Added SYNONYM 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(+)-germacrene-A-forming] activity
2020-10-08 Deleted SYNONYM germacrene A synthase activity
2020-10-08 Added SYNONYM germacrene A synthase activity
2020-10-08 Deleted SYNONYM 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (germacrene-A-forming) activity
2020-10-08 Deleted SYNONYM (+)-germacrene A synthase activity
2020-10-08 Deleted SYNONYM (+)-(10R)-germacrene A synthase activity
Timestamp Action Category Detail
2007-12-14 Added TERM germacrene-A synthase activity
Timestamp Action Category Detail
2020-10-08 Deleted SYNONYM 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(+)-germacrene-A-forming] activity
2020-10-08 Added SYNONYM 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (germacrene-A-forming) activity
2020-10-08 Added SYNONYM 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(+)-germacrene-A-forming] activity
2020-10-08 Deleted SYNONYM germacrene A synthase activity
2020-10-08 Added SYNONYM germacrene A synthase activity
2020-10-08 Deleted SYNONYM 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (germacrene-A-forming) activity
2020-10-08 Deleted SYNONYM (+)-germacrene A synthase activity
2020-10-08 Deleted SYNONYM (+)-(10R)-germacrene A synthase activity
2020-10-08 Added SYNONYM (+)-(10R)-germacrene A synthase activity
2020-10-08 Added SYNONYM (+)-germacrene A synthase activity
2008-05-13 Added DEFINITION Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate.
2008-05-12 Deleted DEFINITION Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate.
2007-12-27 Added DEFINITION Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate.
2007-12-14 Added SYNONYM (+)-germacrene A synthase activity
2007-12-14 Added SYNONYM germacrene A synthase activity
2007-12-14 Added SYNONYM GAS
2007-12-14 Added SYNONYM 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase [(+)-germacrene-A-forming] activity
2007-12-14 Added SYNONYM 2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (germacrene-A-forming) activity
2007-12-14 Added SYNONYM (+)-(10R)-germacrene A synthase activity
Timestamp Action Category Detail
2010-08-11 Added RELATION is a GO:0010334 (sesquiterpene synthase activity)
2010-08-11 Deleted RELATION is a GO:0016838 (carbon-oxygen lyase activity, acting on phosphates)
2008-04-01 Updated RELATION is a GO:0016838 (carbon-oxygen lyase activity, acting on phosphates)
Timestamp Action Category Detail
2023-08-11 Deleted XREF MetaCyc:4.2.3.23-RXN
2023-08-11 Added XREF MetaCyc:RXN-11527
2019-06-20 Added XREF KEGG_REACTION:R07649
2019-06-20 Deleted XREF KEGG:R07649
2018-07-13 Added XREF RHEA:12516
2018-07-13 Deleted XREF RHEA:12519
2010-10-11 Added XREF KEGG:R07649
2010-10-11 Added XREF RHEA:12519
2009-05-21 Added XREF MetaCyc:4.2.3.23-RXN
2007-12-14 Added XREF EC:4.2.3.23
Timestamp Action Category Detail
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