GO:0034138
JSON
toll-like receptor 3 signaling pathway
Biological Process
Definition (GO:0034138 GONUTS page)
The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 3. PMID:16551253 PMID:17328678
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
toll-like receptor 3 signalling pathway | exact |
TLR3 signaling pathway | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0034138
Child Term | Relationship to GO:0034138 |
---|---|
negative regulation of toll-like receptor 3 signaling pathway
|
negatively_regulates |
positive regulation of toll-like receptor 3 signaling pathway
|
positively_regulates |
regulation of toll-like receptor 3 signaling pathway
|
regulates |
GO Discussions
The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:
Ontology Development Project | |
---|---|
signalling | Link |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0034138 | toll-like receptor 3 signaling pathway | Never in Taxon | 4895 | Schizosaccharomyces | |
GO:0034138 | toll-like receptor 3 signaling pathway | Never in Taxon | 4932 | Saccharomyces cerevisiae |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A8I5ZQ02 | 10116 | A0A8I5ZQ02_RAT | GO:0034138 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5ZWL2 | 10116 | A0A8I5ZWL2_RAT | GO:0034138 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6K6K8 | 10116 | A6K6K8_RAT | GO:0034138 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D3ZPA7 | 10116 | D3ZPA7_RAT | GO:0034138 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | Q6AZY7 | 9606 | SCAR3_HUMAN | GO:0034138 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:25204797 | |
NOT-qualified manual | protein | Q9VJN5 | 7227 | WEK_DROME | GO:0002218 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:16782008 | |
NOT-qualified manual | protein | Q9XF04 | 3702 | CLV3_ARATH | GO:0002221 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000270 from this reference: PMID:22923673 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0034138 based on ALL annotations
The top 100 of 613 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
toll-like receptor 3 signaling pathway
|
81,769.63 | 100.00 | 2,384 | 2,384 |
toll-like receptor 9 signaling pathway
|
59,361.90 | 34.92 | 959 | 1,321 |
toll-like receptor 2 signaling pathway
|
55,977.36 | 31.91 | 892 | 1,303 |
toll-like receptor 7 signaling pathway
|
38,286.53 | 28.45 | 1,002 | 2,140 |
Toll-like receptor binding
|
26,811.17 | 21.32 | 903 | 2,754 |
toll-like receptor signaling pathway
|
5,499.90 | 6.22 | 1,079 | 16,042 |
response to exogenous dsRNA
|
8,607.33 | 5.57 | 252 | 2,394 |
T cell antigen processing and presentation
|
40,709.34 | 4.64 | 116 | 233 |
positive regulation of interleukin-12 production
|
6,472.45 | 4.46 | 221 | 2,792 |
cellular response to exogenous dsRNA
|
6,613.98 | 4.18 | 190 | 2,349 |
Totals | 18365 | 343088 |
No co-occurrence statistics for GO:0034138 based on MANUAL annotations
The top 100 of 496 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
toll-like receptor 3 signaling pathway
|
14,679.53 | 100.00 | 88 | 88 |
toll-like receptor 9 signaling pathway
|
7,489.56 | 22.32 | 25 | 49 |
toll-like receptor 7 signaling pathway
|
7,658.89 | 21.82 | 24 | 46 |
toll-like receptor 2 signaling pathway
|
5,382.50 | 17.46 | 22 | 60 |
Toll-like receptor binding
|
3,899.25 | 12.59 | 17 | 64 |
T cell antigen processing and presentation
|
6,459.00 | 10.78 | 11 | 25 |
CD40 signaling pathway
|
3,290.24 | 9.77 | 13 | 58 |
positive regulation of interleukin-12 production
|
1,423.02 | 7.17 | 19 | 196 |
negative regulation of T cell anergy
|
14,679.54 | 6.82 | 6 | 6 |
positive regulation of B cell activation
|
2,302.67 | 6.11 | 8 | 51 |
Totals | 813 | 13120 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4932 (Saccharomyces cerevisiae) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4895 (Schizosaccharomyces) |
2022-07-26 | Added | DEFINITION | The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 3. |
2022-07-26 | Deleted | DEFINITION | The series of molecular signals initiated by a ligand binding to toll-like receptor 3. |
2022-07-26 | Deleted | RELATION | is a GO:0002224 (toll-like receptor signaling pathway) |
2022-07-26 | Added | RELATION | is a GO:0140894 (endolysosomal toll-like receptor signaling pathway) |
2022-03-14 | Added | DEFINITION | The series of molecular signals initiated by a ligand binding to toll-like receptor 3. |
2022-03-14 | Deleted | DEFINITION | Any series of molecular signals generated as a consequence of binding to toll-like receptor 3. |
2008-05-13 | Added | DEFINITION | Any series of molecular signals generated as a consequence of binding to toll-like receptor 3. |
2008-05-12 | Deleted | DEFINITION | Any series of molecular signals generated as a consequence of binding to toll-like receptor 3. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-01-07 | Added | TERM | toll-like receptor 3 signaling pathway |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-07-26 | Added | DEFINITION | The series of molecular signals initiated by a ligand binding to the endolysosomal toll-like receptor 3. |
2022-07-26 | Deleted | DEFINITION | The series of molecular signals initiated by a ligand binding to toll-like receptor 3. |
2022-03-14 | Added | DEFINITION | The series of molecular signals initiated by a ligand binding to toll-like receptor 3. |
2022-03-14 | Deleted | DEFINITION | Any series of molecular signals generated as a consequence of binding to toll-like receptor 3. |
2008-05-13 | Added | DEFINITION | Any series of molecular signals generated as a consequence of binding to toll-like receptor 3. |
2008-05-12 | Deleted | DEFINITION | Any series of molecular signals generated as a consequence of binding to toll-like receptor 3. |
2008-01-27 | Added | DEFINITION | Any series of molecular signals generated as a consequence of binding to toll-like receptor 3. |
2008-01-07 | Added | SYNONYM | TLR3 signaling pathway |
2008-01-07 | Added | SYNONYM | toll-like receptor 3 signalling pathway |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-07-26 | Deleted | RELATION | is a GO:0002224 (toll-like receptor signaling pathway) |
2022-07-26 | Added | RELATION | is a GO:0140894 (endolysosomal toll-like receptor signaling pathway) |
2008-04-01 | Updated | RELATION | is a GO:0002224 (toll-like receptor signaling pathway) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4932 (Saccharomyces cerevisiae) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4895 (Schizosaccharomyces) |
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