This term is obsolete.
Pivalyl-CoA is a synonym for 2,2-dimethylpropanoyl-CoA.

GO:0034784 JSON

pivalyl-CoA mutase activity

Molecular Function

Definition (GO:0034784 GONUTS page)

Catalysis of the reaction: 3-methylbutanoyl-CoA = 2,2-dimethylpropanoyl-CoA.

Comments

Pivalyl-CoA is a synonym for 2,2-dimethylpropanoyl-CoA.

5,684 annotations

Ancestor Chart

Ancestor chart for GO:0034784
Chart options
Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Annotating to catalytic activities using the IPI evidence code Link
Describing enzyme functions that catalyse multi-stage reactions Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P02521 9031 ARLY1_CHICK GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q7KGG1 7227 Q7KGG1_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370
NOT-qualified manual protein Q7SIE0 9103 ARLY1_MELGA GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884
NOT-qualified manual protein Q8MZ84 7227 Q8MZ84_DROME GO:0003824 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370

Cross-references

Database ID Description
InterPro IPR033669 Fused isobutyryl-CoA mutase
MetaCyc RXN-18585
RHEA 52620
UM-BBD_reactionID r1033

Cross-Ontology Relations

Relation Other Ontology ID Term
has_participant CHEBI CHEBI:136712 pivaloyl-CoA(4-)
has_participant CHEBI CHEBI:57345 isovaleryl-CoA(4-)

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0034784 based on ALL annotations
The top 22 of 22 co-occurring terms
Co-occurring Term PR S% #Together #Compared
pivalyl-CoA mutase activity
34,892.56 100.00 5,679 5,679
isobutyryl-CoA mutase activity
34,770.07 99.61 5,677 5,697
acyl-CoA metabolic process
1,852.40 5.31 5,679 106,972
methylmalonyl-CoA mutase activity
1,766.62 4.71 2,293 45,289
cobalamin binding
700.45 2.01 5,679 282,897
GTPase activity
125.58 0.36 5,677 1,577,317
GTP binding
78.50 0.22 5,677 2,523,530
isomerase activity
61.09 0.18 5,679 3,243,534
magnesium ion binding
60.69 0.17 5,580 3,208,148
hydrolase activity
16.67 0.05 5,580 11,680,370
Totals 58940 88128299
No co-occurrence statistics for GO:0034784 based on MANUAL annotations
The top 8 of 8 co-occurring terms
Co-occurring Term PR S% #Together #Compared
pivalyl-CoA mutase activity
282,306.60 100.00 5 5
isobutyryl-CoA mutase activity
169,383.97 42.86 3 5
cobalamin binding
8,303.14 2.92 4 136
acyl-CoA metabolic process
2,057.63 0.73 5 686
protein homodimerization activity
107.44 0.04 2 5,255
magnesium ion binding
92.83 0.03 1 3,041
GTP binding
80.22 0.03 3 10,558
GTPase activity
54.49 0.02 3 15,544
Totals 26 35230

Change Log

Timestamp Action Category Detail
2024-06-12 Added XREF RHEA:52620
2024-06-12 Deleted XREF EC:5.4.99.-
2024-06-12 Added XREF MetaCyc:RXN-18585
2024-06-12 Deleted DEFINITION Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA.
2024-06-12 Added DEFINITION Catalysis of the reaction: 3-methylbutanoyl-CoA = 2,2-dimethylpropanoyl-CoA.
2021-01-04 Deleted XREF EC:5.4.99
2021-01-04 Added XREF EC:5.4.99.-
2016-10-03 Deleted XREF EC:5.4.99.-
2016-10-03 Added XREF EC:5.4.99
2010-09-15 Deleted XREF UM-BBD_enzymeID:e0643
Timestamp Action Category Detail
2008-10-02 Added TERM pivalyl-CoA mutase activity
Timestamp Action Category Detail
2024-06-12 Deleted DEFINITION Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA.
2024-06-12 Added DEFINITION Catalysis of the reaction: 3-methylbutanoyl-CoA = 2,2-dimethylpropanoyl-CoA.
2008-10-02 Added DEFINITION Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA.
Timestamp Action Category Detail
2008-10-02 Added RELATION is a GO:0016866 (intramolecular transferase activity)
Timestamp Action Category Detail
2024-06-12 Added XREF RHEA:52620
2024-06-12 Deleted XREF EC:5.4.99.-
2024-06-12 Added XREF MetaCyc:RXN-18585
2021-01-04 Deleted XREF EC:5.4.99
2021-01-04 Added XREF EC:5.4.99.-
2016-10-03 Deleted XREF EC:5.4.99.-
2016-10-03 Added XREF EC:5.4.99
2010-09-15 Deleted XREF UM-BBD_enzymeID:e0643
2010-09-15 Added XREF UM-BBD_reactionID:r1033
2008-10-02 Added XREF EC:5.4.99.-
2008-10-02 Added XREF UM-BBD_enzymeID:e0643
Timestamp Action Category Detail
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