Pivalyl-CoA is a synonym for 2,2-dimethylpropanoyl-CoA.
GO:0034784
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pivalyl-CoA mutase activity
Molecular Function
Definition (GO:0034784 GONUTS page)
Catalysis of the reaction: 3-methylbutanoyl-CoA = 2,2-dimethylpropanoyl-CoA.
Comments
Pivalyl-CoA is a synonym for 2,2-dimethylpropanoyl-CoA.
Ancestor Chart
Ancestor chart for GO:0034784
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR033669 | Fused isobutyryl-CoA mutase |
MetaCyc | RXN-18585 | |
RHEA | 52620 | |
UM-BBD_reactionID | r1033 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:136712 | pivaloyl-CoA(4-) |
has_participant | CHEBI | CHEBI:57345 | isovaleryl-CoA(4-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0034784 based on ALL annotations
The top 22 of 22 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
pivalyl-CoA mutase activity
|
34,892.56 | 100.00 | 5,679 | 5,679 |
isobutyryl-CoA mutase activity
|
34,770.07 | 99.61 | 5,677 | 5,697 |
acyl-CoA metabolic process
|
1,852.40 | 5.31 | 5,679 | 106,972 |
methylmalonyl-CoA mutase activity
|
1,766.62 | 4.71 | 2,293 | 45,289 |
cobalamin binding
|
700.45 | 2.01 | 5,679 | 282,897 |
GTPase activity
|
125.58 | 0.36 | 5,677 | 1,577,317 |
GTP binding
|
78.50 | 0.22 | 5,677 | 2,523,530 |
isomerase activity
|
61.09 | 0.18 | 5,679 | 3,243,534 |
magnesium ion binding
|
60.69 | 0.17 | 5,580 | 3,208,148 |
hydrolase activity
|
16.67 | 0.05 | 5,580 | 11,680,370 |
Totals | 58940 | 88128299 |
No co-occurrence statistics for GO:0034784 based on MANUAL annotations
The top 8 of 8 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
pivalyl-CoA mutase activity
|
282,306.60 | 100.00 | 5 | 5 |
isobutyryl-CoA mutase activity
|
169,383.97 | 42.86 | 3 | 5 |
cobalamin binding
|
8,303.14 | 2.92 | 4 | 136 |
acyl-CoA metabolic process
|
2,057.63 | 0.73 | 5 | 686 |
protein homodimerization activity
|
107.44 | 0.04 | 2 | 5,255 |
magnesium ion binding
|
92.83 | 0.03 | 1 | 3,041 |
GTP binding
|
80.22 | 0.03 | 3 | 10,558 |
GTPase activity
|
54.49 | 0.02 | 3 | 15,544 |
Totals | 26 | 35230 |
Change Log
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- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-06-12 | Added | XREF | RHEA:52620 |
2024-06-12 | Deleted | XREF | EC:5.4.99.- |
2024-06-12 | Added | XREF | MetaCyc:RXN-18585 |
2024-06-12 | Deleted | DEFINITION | Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA. |
2024-06-12 | Added | DEFINITION | Catalysis of the reaction: 3-methylbutanoyl-CoA = 2,2-dimethylpropanoyl-CoA. |
2021-01-04 | Deleted | XREF | EC:5.4.99 |
2021-01-04 | Added | XREF | EC:5.4.99.- |
2016-10-03 | Deleted | XREF | EC:5.4.99.- |
2016-10-03 | Added | XREF | EC:5.4.99 |
2010-09-15 | Deleted | XREF | UM-BBD_enzymeID:e0643 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-10-02 | Added | TERM | pivalyl-CoA mutase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-06-12 | Deleted | DEFINITION | Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA. |
2024-06-12 | Added | DEFINITION | Catalysis of the reaction: 3-methylbutanoyl-CoA = 2,2-dimethylpropanoyl-CoA. |
2008-10-02 | Added | DEFINITION | Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-10-02 | Added | RELATION | is a GO:0016866 (intramolecular transferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-06-12 | Added | XREF | RHEA:52620 |
2024-06-12 | Deleted | XREF | EC:5.4.99.- |
2024-06-12 | Added | XREF | MetaCyc:RXN-18585 |
2021-01-04 | Deleted | XREF | EC:5.4.99 |
2021-01-04 | Added | XREF | EC:5.4.99.- |
2016-10-03 | Deleted | XREF | EC:5.4.99.- |
2016-10-03 | Added | XREF | EC:5.4.99 |
2010-09-15 | Deleted | XREF | UM-BBD_enzymeID:e0643 |
2010-09-15 | Added | XREF | UM-BBD_reactionID:r1033 |
2008-10-02 | Added | XREF | EC:5.4.99.- |
2008-10-02 | Added | XREF | UM-BBD_enzymeID:e0643 |
Timestamp | Action | Category | Detail |
---|
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