Pivalyl-CoA is a synonym for 2,2-dimethylpropanoyl-CoA.
GO:0034784
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pivalyl-CoA mutase activity
Molecular Function
Definition (GO:0034784 GONUTS page)
Catalysis of the reaction: 3-methylbutanoyl-CoA = 2,2-dimethylpropanoyl-CoA.
Comments
Pivalyl-CoA is a synonym for 2,2-dimethylpropanoyl-CoA.
Ancestor Chart
Ancestor chart for GO:0034784
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q8MZ84 | 7227 | Q8MZ84_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR033669 | Fused isobutyryl-CoA mutase |
MetaCyc | RXN-18585 | |
RHEA | 52620 | |
UM-BBD_reactionID | r1033 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:57345 | isovaleryl-CoA(4-) |
has_participant | CHEBI | CHEBI:136712 | pivaloyl-CoA(4-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0034784 based on ALL annotations
The top 23 of 23 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
pivalyl-CoA mutase activity
|
34,810.50 | 100.00 | 5,600 | 5,600 |
isobutyryl-CoA mutase activity
|
34,686.57 | 99.61 | 5,598 | 5,618 |
membrane scission GTPase motor activity
|
3,825.50 | 10.31 | 3,504 | 31,885 |
acyl-CoA metabolic process
|
1,863.39 | 5.35 | 5,600 | 104,615 |
methylmalonyl-CoA mutase activity
|
1,756.84 | 4.69 | 2,229 | 44,166 |
cobalamin binding
|
714.31 | 2.05 | 5,600 | 272,906 |
GTPase activity
|
126.64 | 0.36 | 5,598 | 1,538,801 |
GTP binding
|
78.22 | 0.22 | 5,598 | 2,491,223 |
isomerase activity
|
61.24 | 0.18 | 5,600 | 3,183,067 |
magnesium ion binding
|
60.83 | 0.17 | 5,510 | 3,152,949 |
Totals | 61696 | 88919538 |
No co-occurrence statistics for GO:0034784 based on MANUAL annotations
The top 8 of 8 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
pivalyl-CoA mutase activity
|
258,359.80 | 100.00 | 5 | 5 |
isobutyryl-CoA mutase activity
|
155,015.89 | 42.86 | 3 | 5 |
cobalamin binding
|
8,137.32 | 3.13 | 4 | 127 |
acyl-CoA metabolic process
|
2,060.29 | 0.80 | 5 | 627 |
protein homodimerization activity
|
97.15 | 0.04 | 2 | 5,319 |
GTP binding
|
92.32 | 0.04 | 3 | 8,396 |
magnesium ion binding
|
88.15 | 0.03 | 1 | 2,931 |
GTPase activity
|
54.62 | 0.02 | 3 | 14,190 |
Totals | 26 | 31600 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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- Other
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-06-12 | Added | XREF | RHEA:52620 |
2024-06-12 | Deleted | DEFINITION | Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA. |
2024-06-12 | Added | XREF | MetaCyc:RXN-18585 |
2024-06-12 | Added | DEFINITION | Catalysis of the reaction: 3-methylbutanoyl-CoA = 2,2-dimethylpropanoyl-CoA. |
2024-06-12 | Deleted | XREF | EC:5.4.99.- |
2021-01-04 | Deleted | XREF | EC:5.4.99 |
2021-01-04 | Added | XREF | EC:5.4.99.- |
2016-10-03 | Added | XREF | EC:5.4.99 |
2016-10-03 | Deleted | XREF | EC:5.4.99.- |
2010-09-15 | Added | XREF | UM-BBD_reactionID:r1033 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-10-02 | Added | TERM | pivalyl-CoA mutase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-06-12 | Deleted | DEFINITION | Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA. |
2024-06-12 | Added | DEFINITION | Catalysis of the reaction: 3-methylbutanoyl-CoA = 2,2-dimethylpropanoyl-CoA. |
2008-10-02 | Added | DEFINITION | Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-10-02 | Added | RELATION | is a GO:0016866 (intramolecular transferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-06-12 | Added | XREF | RHEA:52620 |
2024-06-12 | Added | XREF | MetaCyc:RXN-18585 |
2024-06-12 | Deleted | XREF | EC:5.4.99.- |
2021-01-04 | Deleted | XREF | EC:5.4.99 |
2021-01-04 | Added | XREF | EC:5.4.99.- |
2016-10-03 | Added | XREF | EC:5.4.99 |
2016-10-03 | Deleted | XREF | EC:5.4.99.- |
2010-09-15 | Added | XREF | UM-BBD_reactionID:r1033 |
2010-09-15 | Deleted | XREF | UM-BBD_enzymeID:e0643 |
2008-10-02 | Added | XREF | UM-BBD_enzymeID:e0643 |
2008-10-02 | Added | XREF | EC:5.4.99.- |
Timestamp | Action | Category | Detail |
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