GO:0035019
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somatic stem cell population maintenance
Biological Process
Definition (GO:0035019 GONUTS page)
Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0035019
Child Term | Relationship to GO:0035019 |
---|---|
positive regulation of somatic stem cell population maintenance
|
positively_regulates |
mesenchymal stem cell maintenance involved in nephron morphogenesis
|
is_a |
negative regulation of somatic stem cell population maintenance
|
negatively_regulates |
skeletal muscle satellite stem cell maintenance involved in skeletal muscle regeneration
|
is_a |
regulation of somatic stem cell population maintenance
|
regulates |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0035019 | somatic stem cell population maintenance | Never in Taxon | 2 | Bacteria | |
GO:0035019 | somatic stem cell population maintenance | Never in Taxon | 2157 | Archaea | |
GO:0035019 | somatic stem cell population maintenance | Never in Taxon | 4896 | Schizosaccharomyces pombe | |
GO:0035019 | somatic stem cell population maintenance | Never in Taxon | 4932 | Saccharomyces cerevisiae |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | Q9SB92 | 3702 | WUS_ARATH | GO:0019827 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:15705957 |
Cross-references
Database | ID | Description |
---|---|---|
Reactome | R-HSA-452723 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
acts_on_population_of | CL | CL:0000723 | somatic stem cell |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0035019 based on ALL annotations
The top 100 of 2,176 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
somatic stem cell population maintenance
|
43,675.31 | 100.00 | 4,537 | 4,537 |
pituitary gland development
|
9,842.54 | 9.57 | 647 | 2,871 |
positive regulation of epithelial cell proliferation
|
4,443.96 | 6.61 | 721 | 7,086 |
negative regulation of stem cell differentiation
|
10,724.23 | 6.55 | 372 | 1,515 |
glandular epithelial cell differentiation
|
15,181.50 | 6.45 | 333 | 958 |
ventricular septum morphogenesis
|
7,171.81 | 6.43 | 434 | 2,643 |
epithelial cell proliferation
|
4,461.92 | 5.98 | 572 | 5,599 |
outflow tract morphogenesis
|
4,713.74 | 5.56 | 467 | 4,327 |
pharyngeal arch artery morphogenesis
|
13,946.32 | 5.47 | 281 | 880 |
stem cell proliferation
|
4,278.59 | 5.23 | 457 | 4,665 |
Totals | 30847 | 245099 |
No co-occurrence statistics for GO:0035019 based on MANUAL annotations
The top 100 of 1,973 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
somatic stem cell population maintenance
|
4,176.13 | 100.00 | 338 | 338 |
pituitary gland development
|
1,020.83 | 7.50 | 33 | 135 |
epithelial cell proliferation
|
606.44 | 7.37 | 44 | 303 |
stem cell population maintenance
|
517.40 | 6.61 | 42 | 339 |
stem cell differentiation
|
544.07 | 6.32 | 37 | 284 |
germ-line stem cell population maintenance
|
771.39 | 6.22 | 29 | 157 |
hair follicle development
|
499.85 | 5.48 | 31 | 259 |
ERK1 and ERK2 cascade
|
496.02 | 5.46 | 31 | 261 |
negative regulation of astrocyte differentiation
|
1,575.90 | 5.39 | 20 | 53 |
positive regulation of epithelial cell proliferation
|
364.36 | 5.23 | 39 | 447 |
Totals | 2238 | 21136 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-12-05 | Added | XREF | Reactome:R-HSA-452723 |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2 (Bacteria) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2157 (Archaea) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4932 (Saccharomyces cerevisiae) |
2015-09-13 | Updated | TERM | somatic stem cell population maintenance |
2014-07-19 | Added | DEFINITION | Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. |
2014-07-19 | Deleted | DEFINITION | The process in which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. |
2010-12-01 | Added | DEFINITION | The process in which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. |
2010-12-01 | Deleted | DEFINITION | The process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2015-09-13 | Updated | TERM | somatic stem cell population maintenance |
2003-09-16 | Added | TERM | somatic stem cell maintenance |
Timestamp | Action | Category | Detail |
---|---|---|---|
2014-07-19 | Added | DEFINITION | Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. |
2014-07-19 | Deleted | DEFINITION | The process in which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. |
2010-12-01 | Added | DEFINITION | The process in which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. |
2010-12-01 | Deleted | DEFINITION | The process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. |
2008-05-13 | Added | DEFINITION | The process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. |
2008-05-12 | Deleted | DEFINITION | The process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. |
2003-09-16 | Added | DEFINITION | The process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0019827 (stem cell population maintenance) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-12-05 | Added | XREF | Reactome:R-HSA-452723 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2 (Bacteria) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:2157 (Archaea) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4896 (Schizosaccharomyces pombe) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4932 (Saccharomyces cerevisiae) |
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