This term is obsolete.

GO:0035061 JSON

interchromatin granule

Cellular Component

Definition (GO:0035061 GONUTS page)

A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs). PMID:10984439

253 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
ICG exact

Ancestor Chart

Ancestor chart for GO:0035061
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Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0035061 interchromatin granule Only in Taxon 2759 Eukaryota

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2JW23 10116 A0A0G2JW23_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2K8T1 10116 A0A0G2K8T1_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1B0GR71 10090 A0A1B0GR71_MOUSE GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636
NOT-qualified manual protein A0A1B0GRK6 10090 A0A1B0GRK6_MOUSE GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636
NOT-qualified manual protein A0A1D8PHF8 237561 A0A1D8PHF8_CANAL GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936
NOT-qualified manual protein A0A1W2Q633 10116 A0A1W2Q633_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I5Y8H4 10116 A0A8I5Y8H4_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6A0E5 10116 A0A8I6A0E5_RAT GO:0005634 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
NIF_Subcellular sao1049471211

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0035061 based on ALL annotations
The top 100 of 106 co-occurring terms
Co-occurring Term PR S% #Together #Compared
interchromatin granule
789,225.80 100.00 247 247
sex chromosome
783,291.90 53.23 132 133
exon-exon junction complex binding
705,265.60 32.68 84 94
DNA secondary structure binding
234,681.69 23.85 135 454
perichromatin fibrils
210,602.05 19.08 99 371
negative regulation by host of viral genome replication
172,963.45 18.54 135 616
positive regulation of RNA export from nucleus
164,264.72 15.05 87 418
mRNA alternative polyadenylation
158,208.88 14.65 87 434
positive regulation of chromosome segregation
90,522.92 10.47 135 1,177
paraspeckles
64,898.54 7.14 87 1,058
Totals 5747 90161937
No co-occurrence statistics for GO:0035061 based on MANUAL annotations
The top 89 of 89 co-occurring terms
Co-occurring Term PR S% #Together #Compared
interchromatin granule
39,145.42 100.00 33 33
sex chromosome
39,145.43 36.36 12 12
perichromatin fibrils
18,067.12 33.33 18 39
exon-exon junction complex binding
28,469.40 22.22 8 11
DNA secondary structure binding
14,498.31 20.00 10 27
positive regulation of RNA export from nucleus
10,252.37 17.19 11 42
negative regulation by host of viral genome replication
10,873.73 16.95 10 36
paraspeckles
8,124.52 14.67 11 53
nuclear inner membrane organization
11,743.63 12.77 6 20
positive regulation of maintenance of mitotic sister chromatid cohesion
9,033.56 11.32 6 26
Totals 672 977281

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
2010-02-04 Added XREF NIF_Subcellular:sao1049471211
2008-05-13 Added DEFINITION A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).
2008-05-12 Deleted DEFINITION A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).
2008-04-01 Updated RELATION is a GO:0016604 (nuclear body)
2007-08-09 Added SYNONYM ICG
2007-08-09 Deleted SYNONYM ICG
2004-04-19 Added SYNONYM ICG
2004-04-16 Deleted SYNONYM ICG
2004-02-06 Updated DEFINITION A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).
Timestamp Action Category Detail
2003-12-02 Added TERM interchromatin granule
Timestamp Action Category Detail
2008-05-13 Added DEFINITION A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).
2008-05-12 Deleted DEFINITION A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).
2007-08-09 Added SYNONYM ICG
2007-08-09 Deleted SYNONYM ICG
2004-04-19 Added SYNONYM ICG
2004-04-16 Deleted SYNONYM ICG
2004-02-06 Updated DEFINITION A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).
2004-01-27 Updated DEFINITION A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centres for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).
2003-12-02 Added DEFINITION A class of nuclear body measuring 20-25 nm in diameter and distributed throught the interchromatin space, linked together by thin fibrils. They are believed to be storage centres for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).
2003-12-02 Added SYNONYM ICG
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0016604 (nuclear body)
Timestamp Action Category Detail
2010-02-04 Added XREF NIF_Subcellular:sao1049471211
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:2759 (Eukaryota)
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