GO:0035061
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interchromatin granule
Cellular Component
Definition (GO:0035061 GONUTS page)
A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs). PMID:10984439
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
ICG | exact |
Ancestor Chart
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0035061 | interchromatin granule | Only in Taxon | 2759 | Eukaryota |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A096MJ18 | 10116 | A0A096MJ18_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A096MK97 | 10116 | A0A096MK97_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2JW23 | 10116 | A0A0G2JW23_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2K8T1 | 10116 | A0A0G2K8T1_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1B0GR71 | 10090 | A0A1B0GR71_MOUSE | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636 | |
NOT-qualified manual | protein | A0A1B0GRK6 | 10090 | A0A1B0GRK6_MOUSE | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16904636 | |
NOT-qualified manual | protein | A0A1D8PHF8 | 237561 | A0A1D8PHF8_CANAL | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936 | |
NOT-qualified manual | protein | A0A1W2Q633 | 10116 | A0A1W2Q633_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I5Y8H4 | 10116 | A0A8I5Y8H4_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6A0E5 | 10116 | A0A8I6A0E5_RAT | GO:0005634 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
NIF_Subcellular | sao1049471211 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0035061 based on ALL annotations
The top 100 of 106 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
interchromatin granule
|
789,225.80 | 100.00 | 247 | 247 |
sex chromosome
|
783,291.90 | 53.23 | 132 | 133 |
exon-exon junction complex binding
|
705,265.60 | 32.68 | 84 | 94 |
DNA secondary structure binding
|
234,681.69 | 23.85 | 135 | 454 |
perichromatin fibrils
|
210,602.05 | 19.08 | 99 | 371 |
negative regulation by host of viral genome replication
|
172,963.45 | 18.54 | 135 | 616 |
positive regulation of RNA export from nucleus
|
164,264.72 | 15.05 | 87 | 418 |
mRNA alternative polyadenylation
|
158,208.88 | 14.65 | 87 | 434 |
positive regulation of chromosome segregation
|
90,522.92 | 10.47 | 135 | 1,177 |
paraspeckles
|
64,898.54 | 7.14 | 87 | 1,058 |
Totals | 5747 | 90161937 |
No co-occurrence statistics for GO:0035061 based on MANUAL annotations
The top 89 of 89 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
interchromatin granule
|
39,145.42 | 100.00 | 33 | 33 |
sex chromosome
|
39,145.43 | 36.36 | 12 | 12 |
perichromatin fibrils
|
18,067.12 | 33.33 | 18 | 39 |
exon-exon junction complex binding
|
28,469.40 | 22.22 | 8 | 11 |
DNA secondary structure binding
|
14,498.31 | 20.00 | 10 | 27 |
positive regulation of RNA export from nucleus
|
10,252.37 | 17.19 | 11 | 42 |
negative regulation by host of viral genome replication
|
10,873.73 | 16.95 | 10 | 36 |
paraspeckles
|
8,124.52 | 14.67 | 11 | 53 |
nuclear inner membrane organization
|
11,743.63 | 12.77 | 6 | 20 |
positive regulation of maintenance of mitotic sister chromatid cohesion
|
9,033.56 | 11.32 | 6 | 26 |
Totals | 672 | 977281 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
2010-02-04 | Added | XREF | NIF_Subcellular:sao1049471211 |
2008-05-13 | Added | DEFINITION | A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs). |
2008-05-12 | Deleted | DEFINITION | A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs). |
2008-04-01 | Updated | RELATION | is a GO:0016604 (nuclear body) |
2007-08-09 | Added | SYNONYM | ICG |
2007-08-09 | Deleted | SYNONYM | ICG |
2004-04-19 | Added | SYNONYM | ICG |
2004-04-16 | Deleted | SYNONYM | ICG |
2004-02-06 | Updated | DEFINITION | A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs). |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-12-02 | Added | TERM | interchromatin granule |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs). |
2008-05-12 | Deleted | DEFINITION | A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs). |
2007-08-09 | Added | SYNONYM | ICG |
2007-08-09 | Deleted | SYNONYM | ICG |
2004-04-19 | Added | SYNONYM | ICG |
2004-04-16 | Deleted | SYNONYM | ICG |
2004-02-06 | Updated | DEFINITION | A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs). |
2004-01-27 | Updated | DEFINITION | A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centres for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs). |
2003-12-02 | Added | DEFINITION | A class of nuclear body measuring 20-25 nm in diameter and distributed throught the interchromatin space, linked together by thin fibrils. They are believed to be storage centres for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs). |
2003-12-02 | Added | SYNONYM | ICG |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0016604 (nuclear body) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-02-04 | Added | XREF | NIF_Subcellular:sao1049471211 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:2759 (Eukaryota) |
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