GO:0035173
JSON
histone kinase activity
Molecular Function
Definition (GO:0035173 GONUTS page)
Catalysis of the transfer of a phosphate group to a histone.
Ancestor Chart
Ancestor chart for GO:0035173
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0035173
Child Term | Relationship to GO:0035173 |
---|---|
histone H3 kinase activity
|
is_a |
histone H2A kinase activity
|
is_a |
histone H2B kinase activity
|
is_a |
histone H4 kinase activity
|
is_a |
histone H2AX kinase activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A0A0B4K7S5 | 7227 | A0A0B4K7S5_DROME | GO:0004672 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:19809514 | |
NOT-qualified manual | protein | A0A0G2QC55 | 10116 | A0A0G2QC55_RAT | GO:0004672 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A126GUQ5 | 7227 | A0A126GUQ5_DROME | GO:0004672 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:19809514 | |
NOT-qualified manual | protein | A0A1L8END5 | 8355 | A0A1L8END5_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1L8EV37 | 8355 | A0A1L8EV37_XENLA | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A4D6K026 | 7227 | A0A4D6K026_DROME | GO:0004672 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | A0A6M3Q8Y2 | 7227 | A0A6M3Q8Y2_DROME | GO:0004672 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | A0A8I3Q0M1 | 9615 | A0A8I3Q0M1_CANLF | GO:0016773 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A8I5ZTU0 | 10116 | A0A8I5ZTU0_RAT | GO:0004672 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0035404 | obsolete histone-serine phosphorylation | consider GO:0035173 |
GO:0035406 | obsolete histone-tyrosine phosphorylation | consider GO:0035173 |
GO:1990164 | obsolete histone H2A phosphorylation | consider GO:0035173 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0035173 based on ALL annotations
The top 100 of 518 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
histone kinase activity
|
50,752.09 | 100.00 | 3,841 | 3,841 |
WICH complex
|
46,782.81 | 42.88 | 1,709 | 1,854 |
histone H2AXY142 kinase activity
|
3,530.56 | 6.40 | 1,709 | 24,567 |
cyclin-dependent protein kinase activity
|
29,814.76 | 4.49 | 178 | 303 |
regulation of attachment of mitotic spindle microtubules to kinetochore
|
48,023.49 | 2.29 | 88 | 93 |
mitotic nuclear membrane disassembly
|
43,361.01 | 2.28 | 88 | 103 |
cyclin B1-CDK1 complex
|
27,210.46 | 2.27 | 89 | 166 |
cyclin E2-CDK2 complex
|
22,250.92 | 2.25 | 89 | 203 |
cyclin E1-CDK2 complex
|
19,469.55 | 2.23 | 89 | 232 |
positive regulation of mitochondrial ATP synthesis coupled electron transport
|
19,139.56 | 2.23 | 89 | 236 |
Totals | 46859 | 9881399 |
No co-occurrence statistics for GO:0035173 based on MANUAL annotations
The top 100 of 358 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
histone kinase activity
|
30,757.12 | 100.00 | 42 | 42 |
WICH complex
|
22,145.13 | 36.73 | 18 | 25 |
histone H2AXY142 kinase activity
|
23,067.84 | 13.64 | 6 | 8 |
negative regulation of mitotic chromosome condensation
|
10,984.69 | 9.80 | 5 | 14 |
cyclin-dependent protein kinase activity
|
7,689.28 | 8.77 | 5 | 20 |
B-WICH complex
|
4,660.17 | 7.14 | 5 | 33 |
post-translational protein modification
|
1,851.12 | 5.31 | 13 | 216 |
regulation of macrophage chemotaxis
|
4,856.39 | 5.17 | 3 | 19 |
cyclin B1-CDK1 complex
|
4,613.57 | 5.08 | 3 | 20 |
mammary duct terminal end bud growth
|
4,393.87 | 5.00 | 3 | 21 |
Totals | 278 | 9483 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-02-28 | Deleted | RELATION | part of GO:0016570 (obsolete histone modification) |
2023-02-28 | Added | RELATION | is a GO:0140993 (histone modifying activity) |
2022-09-06 | Added | RELATION | part of GO:0016570 (obsolete histone modification) |
2022-05-26 | Deleted | RELATION | part of GO:0016572 (obsolete histone phosphorylation) |
2022-04-12 | Added | DEFINITION | Catalysis of the transfer of a phosphate group to a histone. |
2022-04-12 | Deleted | DEFINITION | Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. |
2017-05-22 | Deleted | DEFINITION | Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. |
2017-05-22 | Added | DEFINITION | Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. |
2010-06-15 | Added | RELATION | part of GO:0016572 (obsolete histone phosphorylation) |
2010-06-14 | Deleted | RELATION | part of GO:0016572 (obsolete histone phosphorylation) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2004-05-24 | Added | TERM | histone kinase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-04-12 | Added | DEFINITION | Catalysis of the transfer of a phosphate group to a histone. |
2022-04-12 | Deleted | DEFINITION | Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. |
2017-05-22 | Deleted | DEFINITION | Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. |
2017-05-22 | Added | DEFINITION | Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of eukaroytic chromosomes. |
2008-05-13 | Added | DEFINITION | Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. |
2004-05-24 | Added | DEFINITION | Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-02-28 | Deleted | RELATION | part of GO:0016570 (obsolete histone modification) |
2023-02-28 | Added | RELATION | is a GO:0140993 (histone modifying activity) |
2022-09-06 | Added | RELATION | part of GO:0016570 (obsolete histone modification) |
2022-05-26 | Deleted | RELATION | part of GO:0016572 (obsolete histone phosphorylation) |
2010-06-15 | Added | RELATION | part of GO:0016572 (obsolete histone phosphorylation) |
2010-06-14 | Deleted | RELATION | part of GO:0016572 (obsolete histone phosphorylation) |
2010-06-08 | Added | RELATION | part of GO:0016572 (obsolete histone phosphorylation) |
2008-04-01 | Updated | RELATION | is a GO:0004672 (protein kinase activity) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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