GO:0035325
JSON
Toll-like receptor binding
Molecular Function
Definition (GO:0035325 GONUTS page)
Binding to a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response. PMID:19076341
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
TLR binding | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0035325
Child Term | Relationship to GO:0035325 |
---|---|
Toll-like receptor 4 binding
|
is_a |
Toll-like receptor 2 binding
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A8XY28 | 6238 | A8XY28_CAEBR | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PL19 | 6945 | B7PL19_IXOSC | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PVH4 | 6945 | B7PVH4_IXOSC | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | O16262 | 6239 | NIPI4_CAEEL | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | O95970 | 9606 | LGI1_HUMAN | GO:0005102 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20463223 | |
NOT-qualified manual | protein | P21333-1 | 9606 | FLNA_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 | |
NOT-qualified manual | protein | P63026 | 9913 | VAMP2_BOVIN | GO:0005515 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699 | |
NOT-qualified manual | protein | Q86V48 | 9606 | LUZP1_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 | |
NOT-qualified manual | protein | Q8K4Y5 | 10116 | LGI1_RAT | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR043268 | Protein unc-93 homolog B1 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0035325 based on ALL annotations
The top 100 of 501 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
Toll-like receptor binding
|
70,783.87 | 100.00 | 2,754 | 2,754 |
TIR domain binding
|
57,502.04 | 47.20 | 1,459 | 1,796 |
Toll signaling pathway
|
30,014.51 | 30.75 | 1,454 | 3,429 |
MyD88-dependent toll-like receptor signaling pathway
|
30,230.83 | 30.71 | 1,438 | 3,367 |
toll-like receptor 9 signaling pathway
|
48,385.95 | 28.47 | 903 | 1,321 |
toll-like receptor 7 signaling pathway
|
29,868.15 | 22.63 | 903 | 2,140 |
toll-like receptor 3 signaling pathway
|
26,811.17 | 21.32 | 903 | 2,384 |
toll-like receptor 4 signaling pathway
|
12,310.24 | 15.07 | 1,460 | 8,395 |
defense response to Gram-positive bacterium
|
5,436.62 | 7.29 | 1,614 | 21,014 |
toll-like receptor TLR6:TLR2 signaling pathway
|
37,358.16 | 5.88 | 171 | 324 |
Totals | 24652 | 189767 |
No co-occurrence statistics for GO:0035325 based on MANUAL annotations
The top 100 of 457 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
Toll-like receptor binding
|
20,184.36 | 100.00 | 64 | 64 |
Toll signaling pathway
|
4,856.39 | 19.39 | 32 | 133 |
toll-like receptor 7 signaling pathway
|
7,459.44 | 18.28 | 17 | 46 |
toll-like receptor 9 signaling pathway
|
7,002.74 | 17.71 | 17 | 49 |
toll-like receptor 4 signaling pathway
|
2,922.62 | 12.65 | 32 | 221 |
toll-like receptor 3 signaling pathway
|
3,899.25 | 12.59 | 17 | 88 |
toll-like receptor 8 signaling pathway
|
7,689.28 | 10.39 | 8 | 21 |
toll-like receptor TLR6:TLR2 signaling pathway
|
6,374.01 | 7.79 | 6 | 19 |
T cell antigen processing and presentation
|
4,844.25 | 7.23 | 6 | 25 |
positive regulation of cellular response to macrophage colony-stimulating factor stimulus
|
13,456.24 | 6.06 | 4 | 6 |
Totals | 568 | 6381 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response. |
2021-05-24 | Added | DEFINITION | Binding to a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response. |
2010-02-28 | Added | RELATION | is a GO:0005102 (signaling receptor binding) |
2010-02-28 | Added | TERM | Toll-like receptor binding |
2010-02-28 | Added | SYNONYM | TLR binding |
2010-02-28 | Added | DEFINITION | Interacting selectively and non-covalently with a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-02-28 | Added | TERM | Toll-like receptor binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response. |
2021-05-24 | Added | DEFINITION | Binding to a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response. |
2010-02-28 | Added | SYNONYM | TLR binding |
2010-02-28 | Added | DEFINITION | Interacting selectively and non-covalently with a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-02-28 | Added | RELATION | is a GO:0005102 (signaling receptor binding) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|
Not found :(
Sorry, but the Term you were trying to view does not exist.
Reported error:
It looks like this may have been caused by:
- a mistyped URL
- an out-of-date link