GO:0035851
JSON
Krueppel-associated box domain binding
Molecular Function
Definition (GO:0035851 GONUTS page)
Binding to a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| Krueppel-associated box binding | exact |
| KRAB domain binding | exact |
Ancestor Chart
Ancestor chart for GO:0035851
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
| Binding term considerations | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| NOT-qualified manual | protein | P21333-1 | 9606 | FLNA_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 | |
| NOT-qualified manual | protein | P63026 | 9913 | VAMP2_BOVIN | GO:0005515 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699 | |
| NOT-qualified manual | protein | Q86V48 | 9606 | LUZP1_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0035851 based on ALL annotations
The top 100 of 171 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
Krueppel-associated box domain binding
|
1,132,313.50 | 100.00 | 175 | 175 |
|
fungiform papilla formation
|
585,028.70 | 35.50 | 93 | 180 |
|
protein lysine delactylase activity
|
355,538.72 | 24.47 | 92 | 293 |
|
hair follicle placode formation
|
343,125.30 | 20.83 | 70 | 231 |
|
histone decrotonylase activity
|
277,850.00 | 20.17 | 93 | 379 |
|
embryonic placenta morphogenesis
|
314,813.62 | 18.45 | 62 | 223 |
|
epigenetic programming of gene expression
|
280,849.44 | 17.21 | 63 | 254 |
|
chromo shadow domain binding
|
183,497.45 | 13.69 | 82 | 506 |
|
eyelid development in camera-type eye
|
114,213.84 | 9.26 | 93 | 922 |
|
negative regulation by host of viral transcription
|
106,308.91 | 8.56 | 86 | 916 |
| Totals | 6068 | 1303073 | ||
No co-occurrence statistics for GO:0035851 based on MANUAL annotations
The top 100 of 156 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
Krueppel-associated box domain binding
|
141,153.30 | 100.00 | 10 | 10 |
|
fungiform papilla formation
|
82,339.42 | 46.67 | 7 | 12 |
|
hair follicle placode formation
|
47,051.10 | 29.17 | 7 | 21 |
|
protein lysine delactylase activity
|
44,912.41 | 28.00 | 7 | 22 |
|
positive regulation of male mating behavior
|
62,734.81 | 26.67 | 4 | 9 |
|
protein de-2-hydroxyisobutyrylase activity
|
50,411.90 | 26.32 | 5 | 14 |
|
histone H4K16 deacetylase activity, hydrolytic mechanism
|
44,110.41 | 23.81 | 5 | 16 |
|
histone decrotonylase activity
|
32,935.77 | 21.21 | 7 | 30 |
|
positive regulation of interleukin-1 production
|
25,205.95 | 15.15 | 5 | 28 |
|
negative regulation of dendritic spine development
|
26,886.34 | 14.81 | 4 | 21 |
| Totals | 441 | 31415 | ||
Change Log
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- Definition / Synonyms
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors. |
| 2021-05-24 | Added | DEFINITION | Binding to a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors. |
| 2011-05-13 | Added | RELATION | is a GO:0019904 (protein domain specific binding) |
| 2011-05-13 | Added | SYNONYM | KRAB domain binding |
| 2011-05-13 | Added | TERM | Krueppel-associated box domain binding |
| 2011-05-13 | Added | DEFINITION | Interacting selectively and non-covalently with a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors. |
| 2011-05-13 | Added | SYNONYM | Krueppel-associated box binding |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2011-05-13 | Added | TERM | Krueppel-associated box domain binding |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors. |
| 2021-05-24 | Added | DEFINITION | Binding to a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors. |
| 2011-05-13 | Added | SYNONYM | KRAB domain binding |
| 2011-05-13 | Added | DEFINITION | Interacting selectively and non-covalently with a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors. |
| 2011-05-13 | Added | SYNONYM | Krueppel-associated box binding |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2011-05-13 | Added | RELATION | is a GO:0019904 (protein domain specific binding) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|
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