GO:0035987
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endodermal cell differentiation
Biological Process
Definition (GO:0035987 GONUTS page)
The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo. PMID:17624332
Acknowledgement
This term was created by the GO Consortium with support from:
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
endoderm cell differentiation | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0035987
Child Term | Relationship to GO:0035987 |
---|---|
positive regulation of endodermal cell differentiation
|
positively_regulates |
regulation of endodermal cell differentiation
|
regulates |
endodermal cell fate commitment
|
part_of |
negative regulation of endodermal cell differentiation
|
negatively_regulates |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0035987 | endodermal cell differentiation | Only in Taxon | 6072 | Eumetazoa |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A8XY28 | 6238 | A8XY28_CAEBR | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PL19 | 6945 | B7PL19_IXOSC | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PVH4 | 6945 | B7PVH4_IXOSC | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | O16262 | 6239 | NIPI4_CAEEL | GO:0030154 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | P98078-3 | 10090 | DAB2_MOUSE | GO:0007492 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:22525672 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
results_in_acquisition_of_features_of | CL | CL:0000223 | endodermal cell |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0035987 based on ALL annotations
The top 100 of 1,153 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
endodermal cell differentiation
|
44,989.34 | 100.00 | 4,333 | 4,333 |
heterotypic cell-cell adhesion
|
3,582.23 | 4.71 | 449 | 5,639 |
integrin alphav-beta5 complex
|
44,527.91 | 4.45 | 193 | 195 |
response to amyloid-beta
|
10,806.26 | 3.96 | 196 | 816 |
cellular response to UV-A
|
8,812.80 | 3.88 | 200 | 1,021 |
cell migration involved in gastrulation
|
4,568.21 | 3.76 | 244 | 2,403 |
response to muscle activity
|
5,055.77 | 3.59 | 217 | 1,931 |
stem cell differentiation
|
3,097.48 | 3.49 | 286 | 4,154 |
Sertoli cell differentiation
|
12,379.62 | 3.44 | 164 | 596 |
endodermal cell fate determination
|
41,379.08 | 3.43 | 149 | 162 |
Totals | 18579 | 179360 |
No co-occurrence statistics for GO:0035987 based on MANUAL annotations
The top 100 of 1,039 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
endodermal cell differentiation
|
7,925.15 | 100.00 | 163 | 163 |
MH1 domain binding
|
7,925.15 | 7.36 | 12 | 12 |
mesodermal-endodermal cell signaling
|
7,315.52 | 7.32 | 12 | 13 |
heterotypic cell-cell adhesion
|
1,066.85 | 7.05 | 21 | 156 |
MH2 domain binding
|
4,528.66 | 6.98 | 12 | 21 |
senescence-associated heterochromatin focus
|
3,522.29 | 6.74 | 12 | 27 |
SMAD protein complex
|
2,502.68 | 6.35 | 12 | 38 |
oncogene-induced cell senescence
|
2,438.51 | 6.32 | 12 | 39 |
regulation of axon regeneration
|
2,264.33 | 6.22 | 12 | 42 |
negative regulation of double-strand break repair via nonhomologous end joining
|
1,864.74 | 5.94 | 12 | 51 |
Totals | 1054 | 10168 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:6072 (Eumetazoa) |
2013-11-28 | Deleted | RELATION | is a GO:0044767 (single-organism developmental process) |
2013-03-10 | Deleted | RELATION | is a GO:0048646 (anatomical structure formation involved in morphogenesis) |
2012-12-21 | Added | RELATION | is a GO:0044767 (single-organism developmental process) |
2012-10-29 | Added | RELATION | is a GO:0048646 (anatomical structure formation involved in morphogenesis) |
2011-08-28 | Added | SYNONYM | endoderm cell differentiation |
2011-08-28 | Added | RELATION | is a GO:0030154 (cell differentiation) |
2011-08-28 | Added | RELATION | part of GO:0001706 (endoderm formation) |
2011-08-28 | Added | DEFINITION | The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo. |
2011-08-28 | Added | TERM | endodermal cell differentiation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-08-28 | Added | TERM | endodermal cell differentiation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-08-28 | Added | SYNONYM | endoderm cell differentiation |
2011-08-28 | Added | DEFINITION | The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-11-28 | Deleted | RELATION | is a GO:0044767 (single-organism developmental process) |
2013-03-10 | Deleted | RELATION | is a GO:0048646 (anatomical structure formation involved in morphogenesis) |
2012-12-21 | Added | RELATION | is a GO:0044767 (single-organism developmental process) |
2012-10-29 | Added | RELATION | is a GO:0048646 (anatomical structure formation involved in morphogenesis) |
2011-08-28 | Added | RELATION | is a GO:0030154 (cell differentiation) |
2011-08-28 | Added | RELATION | part of GO:0001706 (endoderm formation) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:6072 (Eumetazoa) |
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