This term is obsolete.

GO:0035987 JSON

endodermal cell differentiation

Biological Process

Definition (GO:0035987 GONUTS page)

The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo. PMID:17624332

Acknowledgement

This term was created by the GO Consortium with support from: KRUK image

6,536 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
endoderm cell differentiation exact

Ancestor Chart

Ancestor chart for GO:0035987
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0035987

Child Term Relationship to
GO:0035987
positive regulation of endodermal cell differentiation
positively_regulates
regulation of endodermal cell differentiation
regulates
endodermal cell fate commitment
part_of
negative regulation of endodermal cell differentiation
negatively_regulates

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0035987 endodermal cell differentiation Only in Taxon 6072 Eumetazoa

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A8XY28 6238 A8XY28_CAEBR GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PL19 6945 B7PL19_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PVH4 6945 B7PVH4_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O16262 6239 NIPI4_CAEEL GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein P98078-3 10090 DAB2_MOUSE GO:0007492 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:22525672

Cross-Ontology Relations

Relation Other Ontology ID Term
results_in_acquisition_of_features_of CL CL:0000223 endodermal cell

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0035987 based on ALL annotations
The top 100 of 1,153 co-occurring terms
Co-occurring Term PR S% #Together #Compared
endodermal cell differentiation
44,989.34 100.00 4,333 4,333
heterotypic cell-cell adhesion
3,582.23 4.71 449 5,639
integrin alphav-beta5 complex
44,527.91 4.45 193 195
response to amyloid-beta
10,806.26 3.96 196 816
cellular response to UV-A
8,812.80 3.88 200 1,021
cell migration involved in gastrulation
4,568.21 3.76 244 2,403
response to muscle activity
5,055.77 3.59 217 1,931
stem cell differentiation
3,097.48 3.49 286 4,154
Sertoli cell differentiation
12,379.62 3.44 164 596
endodermal cell fate determination
41,379.08 3.43 149 162
Totals 18579 179360
No co-occurrence statistics for GO:0035987 based on MANUAL annotations
The top 100 of 1,039 co-occurring terms
Co-occurring Term PR S% #Together #Compared
endodermal cell differentiation
7,925.15 100.00 163 163
MH1 domain binding
7,925.15 7.36 12 12
mesodermal-endodermal cell signaling
7,315.52 7.32 12 13
heterotypic cell-cell adhesion
1,066.85 7.05 21 156
MH2 domain binding
4,528.66 6.98 12 21
senescence-associated heterochromatin focus
3,522.29 6.74 12 27
SMAD protein complex
2,502.68 6.35 12 38
oncogene-induced cell senescence
2,438.51 6.32 12 39
regulation of axon regeneration
2,264.33 6.22 12 42
negative regulation of double-strand break repair via nonhomologous end joining
1,864.74 5.94 12 51
Totals 1054 10168

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:6072 (Eumetazoa)
2013-11-28 Deleted RELATION is a GO:0044767 (single-organism developmental process)
2013-03-10 Deleted RELATION is a GO:0048646 (anatomical structure formation involved in morphogenesis)
2012-12-21 Added RELATION is a GO:0044767 (single-organism developmental process)
2012-10-29 Added RELATION is a GO:0048646 (anatomical structure formation involved in morphogenesis)
2011-08-28 Added SYNONYM endoderm cell differentiation
2011-08-28 Added RELATION is a GO:0030154 (cell differentiation)
2011-08-28 Added RELATION part of GO:0001706 (endoderm formation)
2011-08-28 Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo.
2011-08-28 Added TERM endodermal cell differentiation
Timestamp Action Category Detail
2011-08-28 Added TERM endodermal cell differentiation
Timestamp Action Category Detail
2011-08-28 Added SYNONYM endoderm cell differentiation
2011-08-28 Added DEFINITION The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo.
Timestamp Action Category Detail
2013-11-28 Deleted RELATION is a GO:0044767 (single-organism developmental process)
2013-03-10 Deleted RELATION is a GO:0048646 (anatomical structure formation involved in morphogenesis)
2012-12-21 Added RELATION is a GO:0044767 (single-organism developmental process)
2012-10-29 Added RELATION is a GO:0048646 (anatomical structure formation involved in morphogenesis)
2011-08-28 Added RELATION is a GO:0030154 (cell differentiation)
2011-08-28 Added RELATION part of GO:0001706 (endoderm formation)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:6072 (Eumetazoa)
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