This term is obsolete.

GO:0036402 JSON

proteasome-activating activity

Molecular Function

Definition (GO:0036402 GONUTS page)

Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome. PMID:11430818

18,257 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
proteasome channel gating activity narrow
proteasome-activating ATPase activity exact
ATPase involved in positive regulation of proteasomal protein catabolic process exact
proteasomal ATPase activity exact
proteasome channel opening activity narrow

Ancestor Chart

Ancestor chart for GO:0036402
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Ancestor chart

Cross-references

Database ID Description
EC 5.6.1.5

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0036402 based on ALL annotations
The top 100 of 124 co-occurring terms
Co-occurring Term PR S% #Together #Compared
proteasome-activating activity
10,704.45 100.00 18,211 18,211
positive regulation of proteasomal protein catabolic process
10,007.64 93.49 18,211 19,479
protein unfolding
2,422.27 22.27 16,990 75,082
HslUV protease complex
2,196.37 20.22 16,984 82,775
proteolysis involved in protein catabolic process
756.34 7.03 16,983 240,359
proteasome regulatory particle, base subcomplex
376.90 2.28 1,106 31,412
peptidase activity
136.12 1.27 17,215 1,353,802
positive regulation of RNA polymerase II transcription preinitiation complex assembly
1,136.29 0.98 195 1,837
proteasome regulatory particle assembly
344.15 0.95 241 7,496
protein-containing complex localization
934.28 0.93 188 2,154
Totals 178010 110491855
No co-occurrence statistics for GO:0036402 based on MANUAL annotations
The top 86 of 86 co-occurring terms
Co-occurring Term PR S% #Together #Compared
proteasome-activating activity
1,389.03 100.00 930 930
proteasome regulatory particle, base subcomplex
950.28 68.26 927 1,355
positive regulation of RNA polymerase II transcription preinitiation complex assembly
1,198.95 17.15 164 190
cytosolic proteasome complex
1,271.32 17.14 162 177
proteasome-mediated ubiquitin-dependent protein catabolic process
113.02 8.13 927 11,393
ERAD pathway
50.25 3.08 160 4,423
proteasome accessory complex
310.05 2.46 25 112
proteasome complex
86.32 2.31 33 531
proteasome regulatory particle
208.81 2.17 23 153
inclusion body
114.39 0.69 7 85
Totals 3663 900159

Change Log

Timestamp Action Category Detail
2021-06-18 Deleted RELATION is a GO:0016887 (ATP hydrolysis activity)
2021-06-18 Added RELATION is a GO:0140657 (ATP-dependent activity)
2021-03-12 Added SYNONYM proteasome-activating ATPase activity
2021-03-12 Updated TERM proteasome-activating activity
2021-03-08 Added XREF EC:5.6.1.5
2020-03-15 Added RELATION is a GO:0016887 (ATP hydrolysis activity)
2020-03-15 Deleted RELATION is a GO:0042623 (ATPase activity, coupled)
2013-08-14 Added SYNONYM proteasome channel gating activity
2013-08-14 Added SYNONYM ATPase involved in positive regulation of proteasomal protein catabolic process
2013-08-14 Added SYNONYM proteasomal ATPase activity
Timestamp Action Category Detail
2021-03-12 Updated TERM proteasome-activating activity
2013-08-14 Added TERM proteasome-activating ATPase activity
Timestamp Action Category Detail
2021-03-12 Added SYNONYM proteasome-activating ATPase activity
2013-08-14 Added SYNONYM proteasome channel gating activity
2013-08-14 Added SYNONYM ATPase involved in positive regulation of proteasomal protein catabolic process
2013-08-14 Added SYNONYM proteasomal ATPase activity
2013-08-14 Added DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome.
2013-08-14 Added SYNONYM proteasome channel opening activity
Timestamp Action Category Detail
2021-06-18 Deleted RELATION is a GO:0016887 (ATP hydrolysis activity)
2021-06-18 Added RELATION is a GO:0140657 (ATP-dependent activity)
2020-03-15 Added RELATION is a GO:0016887 (ATP hydrolysis activity)
2020-03-15 Deleted RELATION is a GO:0042623 (ATPase activity, coupled)
2013-08-14 Added RELATION is a GO:0042623 (ATPase activity, coupled)
2013-08-14 Added RELATION part of GO:1901800 (positive regulation of proteasomal protein catabolic process)
Timestamp Action Category Detail
2021-03-08 Added XREF EC:5.6.1.5
Timestamp Action Category Detail
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