GO:0036402
JSON
proteasome-activating activity
Molecular Function
Definition (GO:0036402 GONUTS page)
Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome. PMID:11430818
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
proteasomal ATPase activity | exact |
proteasome channel opening activity | narrow |
ATPase involved in positive regulation of proteasomal protein catabolic process | exact |
proteasome channel gating activity | narrow |
proteasome-activating ATPase activity | exact |
Ancestor Chart
Ancestor chart for GO:0036402
Cross-references
Database | ID | Description |
---|---|---|
EC | 5.6.1.5 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0036402 based on ALL annotations
The top 100 of 120 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
proteasome-activating activity
|
10,728.47 | 100.00 | 18,470 | 18,470 |
positive regulation of proteasomal protein catabolic process
|
10,036.72 | 93.55 | 18,470 | 19,743 |
protein unfolding
|
2,420.44 | 22.18 | 17,156 | 76,043 |
HslUV protease complex
|
2,199.30 | 20.18 | 17,150 | 83,660 |
proteolysis involved in protein catabolic process
|
767.12 | 7.11 | 17,148 | 239,821 |
proteasome regulatory particle, base subcomplex
|
399.13 | 2.42 | 1,202 | 32,309 |
peptidase activity
|
131.92 | 1.23 | 17,372 | 1,412,747 |
positive regulation of RNA polymerase II transcription preinitiation complex assembly
|
1,204.99 | 1.03 | 207 | 1,843 |
proteasome regulatory particle assembly
|
334.79 | 0.93 | 240 | 7,691 |
protein-containing complex localization
|
933.56 | 0.92 | 187 | 2,149 |
Totals | 179455 | 109133349 |
No co-occurrence statistics for GO:0036402 based on MANUAL annotations
The top 86 of 86 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
proteasome-activating activity
|
1,375.76 | 100.00 | 1,026 | 1,026 |
proteasome regulatory particle, base subcomplex
|
950.59 | 69.00 | 1,024 | 1,482 |
positive regulation of RNA polymerase II transcription preinitiation complex assembly
|
1,198.68 | 16.73 | 176 | 202 |
proteasome-mediated ubiquitin-dependent protein catabolic process
|
115.55 | 8.40 | 1,024 | 12,192 |
ERAD pathway
|
50.22 | 3.09 | 172 | 4,712 |
proteasome regulatory particle
|
200.27 | 1.98 | 23 | 158 |
proteasome accessory complex
|
270.24 | 1.97 | 22 | 112 |
proteasome complex
|
70.29 | 1.81 | 28 | 548 |
general transcription initiation factor binding
|
150.08 | 0.56 | 6 | 55 |
proteasome regulatory particle assembly
|
60.25 | 0.52 | 6 | 137 |
Totals | 3786 | 966457 |
Change Log
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- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-06-18 | Added | RELATION | is a GO:0140657 (ATP-dependent activity) |
2021-06-18 | Deleted | RELATION | is a GO:0016887 (ATP hydrolysis activity) |
2021-03-12 | Added | SYNONYM | proteasome-activating ATPase activity |
2021-03-12 | Updated | TERM | proteasome-activating activity |
2021-03-08 | Added | XREF | EC:5.6.1.5 |
2020-03-15 | Deleted | RELATION | is a GO:0042623 (ATPase activity, coupled) |
2020-03-15 | Added | RELATION | is a GO:0016887 (ATP hydrolysis activity) |
2013-08-14 | Added | RELATION | part of GO:1901800 (positive regulation of proteasomal protein catabolic process) |
2013-08-14 | Added | RELATION | is a GO:0042623 (ATPase activity, coupled) |
2013-08-14 | Added | TERM | proteasome-activating ATPase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-03-12 | Updated | TERM | proteasome-activating activity |
2013-08-14 | Added | TERM | proteasome-activating ATPase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-03-12 | Added | SYNONYM | proteasome-activating ATPase activity |
2013-08-14 | Added | DEFINITION | Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome. |
2013-08-14 | Added | SYNONYM | proteasomal ATPase activity |
2013-08-14 | Added | SYNONYM | ATPase involved in positive regulation of proteasomal protein catabolic process |
2013-08-14 | Added | SYNONYM | proteasome channel gating activity |
2013-08-14 | Added | SYNONYM | proteasome channel opening activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-06-18 | Added | RELATION | is a GO:0140657 (ATP-dependent activity) |
2021-06-18 | Deleted | RELATION | is a GO:0016887 (ATP hydrolysis activity) |
2020-03-15 | Deleted | RELATION | is a GO:0042623 (ATPase activity, coupled) |
2020-03-15 | Added | RELATION | is a GO:0016887 (ATP hydrolysis activity) |
2013-08-14 | Added | RELATION | part of GO:1901800 (positive regulation of proteasomal protein catabolic process) |
2013-08-14 | Added | RELATION | is a GO:0042623 (ATPase activity, coupled) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-03-08 | Added | XREF | EC:5.6.1.5 |
Timestamp | Action | Category | Detail |
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