This term is obsolete.

GO:0036402 JSON

proteasome-activating activity

Molecular Function

Definition (GO:0036402 GONUTS page)

Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome. PMID:11430818

18,519 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
proteasomal ATPase activity exact
proteasome channel opening activity narrow
ATPase involved in positive regulation of proteasomal protein catabolic process exact
proteasome channel gating activity narrow
proteasome-activating ATPase activity exact

Ancestor Chart

Ancestor chart for GO:0036402
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Ancestor chart

Cross-references

Database ID Description
EC 5.6.1.5

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0036402 based on ALL annotations
The top 100 of 120 co-occurring terms
Co-occurring Term PR S% #Together #Compared
proteasome-activating activity
10,728.47 100.00 18,470 18,470
positive regulation of proteasomal protein catabolic process
10,036.72 93.55 18,470 19,743
protein unfolding
2,420.44 22.18 17,156 76,043
HslUV protease complex
2,199.30 20.18 17,150 83,660
proteolysis involved in protein catabolic process
767.12 7.11 17,148 239,821
proteasome regulatory particle, base subcomplex
399.13 2.42 1,202 32,309
peptidase activity
131.92 1.23 17,372 1,412,747
positive regulation of RNA polymerase II transcription preinitiation complex assembly
1,204.99 1.03 207 1,843
proteasome regulatory particle assembly
334.79 0.93 240 7,691
protein-containing complex localization
933.56 0.92 187 2,149
Totals 179455 109133349
No co-occurrence statistics for GO:0036402 based on MANUAL annotations
The top 86 of 86 co-occurring terms
Co-occurring Term PR S% #Together #Compared
proteasome-activating activity
1,375.76 100.00 1,026 1,026
proteasome regulatory particle, base subcomplex
950.59 69.00 1,024 1,482
positive regulation of RNA polymerase II transcription preinitiation complex assembly
1,198.68 16.73 176 202
proteasome-mediated ubiquitin-dependent protein catabolic process
115.55 8.40 1,024 12,192
ERAD pathway
50.22 3.09 172 4,712
proteasome regulatory particle
200.27 1.98 23 158
proteasome accessory complex
270.24 1.97 22 112
proteasome complex
70.29 1.81 28 548
general transcription initiation factor binding
150.08 0.56 6 55
proteasome regulatory particle assembly
60.25 0.52 6 137
Totals 3786 966457

Change Log

Timestamp Action Category Detail
2021-06-18 Added RELATION is a GO:0140657 (ATP-dependent activity)
2021-06-18 Deleted RELATION is a GO:0016887 (ATP hydrolysis activity)
2021-03-12 Added SYNONYM proteasome-activating ATPase activity
2021-03-12 Updated TERM proteasome-activating activity
2021-03-08 Added XREF EC:5.6.1.5
2020-03-15 Deleted RELATION is a GO:0042623 (ATPase activity, coupled)
2020-03-15 Added RELATION is a GO:0016887 (ATP hydrolysis activity)
2013-08-14 Added RELATION part of GO:1901800 (positive regulation of proteasomal protein catabolic process)
2013-08-14 Added RELATION is a GO:0042623 (ATPase activity, coupled)
2013-08-14 Added TERM proteasome-activating ATPase activity
Timestamp Action Category Detail
2021-03-12 Updated TERM proteasome-activating activity
2013-08-14 Added TERM proteasome-activating ATPase activity
Timestamp Action Category Detail
2021-03-12 Added SYNONYM proteasome-activating ATPase activity
2013-08-14 Added DEFINITION Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome.
2013-08-14 Added SYNONYM proteasomal ATPase activity
2013-08-14 Added SYNONYM ATPase involved in positive regulation of proteasomal protein catabolic process
2013-08-14 Added SYNONYM proteasome channel gating activity
2013-08-14 Added SYNONYM proteasome channel opening activity
Timestamp Action Category Detail
2021-06-18 Added RELATION is a GO:0140657 (ATP-dependent activity)
2021-06-18 Deleted RELATION is a GO:0016887 (ATP hydrolysis activity)
2020-03-15 Deleted RELATION is a GO:0042623 (ATPase activity, coupled)
2020-03-15 Added RELATION is a GO:0016887 (ATP hydrolysis activity)
2013-08-14 Added RELATION part of GO:1901800 (positive regulation of proteasomal protein catabolic process)
2013-08-14 Added RELATION is a GO:0042623 (ATPase activity, coupled)
Timestamp Action Category Detail
2021-03-08 Added XREF EC:5.6.1.5
Timestamp Action Category Detail
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