GO:0036402
JSON
proteasome-activating activity
Molecular Function
Definition (GO:0036402 GONUTS page)
Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome. PMID:11430818
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
proteasome channel gating activity | narrow |
proteasome-activating ATPase activity | exact |
ATPase involved in positive regulation of proteasomal protein catabolic process | exact |
proteasomal ATPase activity | exact |
proteasome channel opening activity | narrow |
Ancestor Chart
Ancestor chart for GO:0036402
Cross-references
Database | ID | Description |
---|---|---|
EC | 5.6.1.5 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0036402 based on ALL annotations
The top 100 of 124 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
proteasome-activating activity
|
10,704.45 | 100.00 | 18,211 | 18,211 |
positive regulation of proteasomal protein catabolic process
|
10,007.64 | 93.49 | 18,211 | 19,479 |
protein unfolding
|
2,422.27 | 22.27 | 16,990 | 75,082 |
HslUV protease complex
|
2,196.37 | 20.22 | 16,984 | 82,775 |
proteolysis involved in protein catabolic process
|
756.34 | 7.03 | 16,983 | 240,359 |
proteasome regulatory particle, base subcomplex
|
376.90 | 2.28 | 1,106 | 31,412 |
peptidase activity
|
136.12 | 1.27 | 17,215 | 1,353,802 |
positive regulation of RNA polymerase II transcription preinitiation complex assembly
|
1,136.29 | 0.98 | 195 | 1,837 |
proteasome regulatory particle assembly
|
344.15 | 0.95 | 241 | 7,496 |
protein-containing complex localization
|
934.28 | 0.93 | 188 | 2,154 |
Totals | 178010 | 110491855 |
No co-occurrence statistics for GO:0036402 based on MANUAL annotations
The top 86 of 86 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
proteasome-activating activity
|
1,389.03 | 100.00 | 930 | 930 |
proteasome regulatory particle, base subcomplex
|
950.28 | 68.26 | 927 | 1,355 |
positive regulation of RNA polymerase II transcription preinitiation complex assembly
|
1,198.95 | 17.15 | 164 | 190 |
cytosolic proteasome complex
|
1,271.32 | 17.14 | 162 | 177 |
proteasome-mediated ubiquitin-dependent protein catabolic process
|
113.02 | 8.13 | 927 | 11,393 |
ERAD pathway
|
50.25 | 3.08 | 160 | 4,423 |
proteasome accessory complex
|
310.05 | 2.46 | 25 | 112 |
proteasome complex
|
86.32 | 2.31 | 33 | 531 |
proteasome regulatory particle
|
208.81 | 2.17 | 23 | 153 |
inclusion body
|
114.39 | 0.69 | 7 | 85 |
Totals | 3663 | 900159 |
Change Log
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- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-06-18 | Deleted | RELATION | is a GO:0016887 (ATP hydrolysis activity) |
2021-06-18 | Added | RELATION | is a GO:0140657 (ATP-dependent activity) |
2021-03-12 | Added | SYNONYM | proteasome-activating ATPase activity |
2021-03-12 | Updated | TERM | proteasome-activating activity |
2021-03-08 | Added | XREF | EC:5.6.1.5 |
2020-03-15 | Added | RELATION | is a GO:0016887 (ATP hydrolysis activity) |
2020-03-15 | Deleted | RELATION | is a GO:0042623 (ATPase activity, coupled) |
2013-08-14 | Added | SYNONYM | proteasome channel gating activity |
2013-08-14 | Added | SYNONYM | ATPase involved in positive regulation of proteasomal protein catabolic process |
2013-08-14 | Added | SYNONYM | proteasomal ATPase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-03-12 | Updated | TERM | proteasome-activating activity |
2013-08-14 | Added | TERM | proteasome-activating ATPase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-03-12 | Added | SYNONYM | proteasome-activating ATPase activity |
2013-08-14 | Added | SYNONYM | proteasome channel gating activity |
2013-08-14 | Added | SYNONYM | ATPase involved in positive regulation of proteasomal protein catabolic process |
2013-08-14 | Added | SYNONYM | proteasomal ATPase activity |
2013-08-14 | Added | DEFINITION | Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome. |
2013-08-14 | Added | SYNONYM | proteasome channel opening activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-06-18 | Deleted | RELATION | is a GO:0016887 (ATP hydrolysis activity) |
2021-06-18 | Added | RELATION | is a GO:0140657 (ATP-dependent activity) |
2020-03-15 | Added | RELATION | is a GO:0016887 (ATP hydrolysis activity) |
2020-03-15 | Deleted | RELATION | is a GO:0042623 (ATPase activity, coupled) |
2013-08-14 | Added | RELATION | is a GO:0042623 (ATPase activity, coupled) |
2013-08-14 | Added | RELATION | part of GO:1901800 (positive regulation of proteasomal protein catabolic process) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-03-08 | Added | XREF | EC:5.6.1.5 |
Timestamp | Action | Category | Detail |
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