This term is obsolete.

GO:0036465 JSON

synaptic vesicle recycling

Biological Process

Definition (GO:0036465 GONUTS page)

The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane. PMID:15217342 PMID:22026965 PMID:23245563

Acknowledgement

This term was created by the GO Consortium with support from: PARK image

62,973 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
kiss-and-stay synaptic vesicle recycling narrow
kiss-and-run synaptic vesicle recycling narrow

Ancestor Chart

Ancestor chart for GO:0036465
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0036465

Child Term Relationship to
GO:0036465
regulation of synaptic vesicle recycling
regulates
positive regulation of synaptic vesicle recycling
positively_regulates
synaptic vesicle recycling via endosome
is_a
synaptic vesicle endocytosis
part_of
negative regulation of synaptic vesicle recycling
negatively_regulates

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0036465 synaptic vesicle recycling Only in Taxon 33208 Metazoa

More information on taxon constraints in GO is available here

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0036465 based on ALL annotations
The top 100 of 673 co-occurring terms
Co-occurring Term PR S% #Together #Compared
synaptic vesicle recycling
34,008.86 100.00 5,732 5,732
regulation of G protein-coupled receptor signaling pathway
5,889.36 17.17 5,462 31,541
regulation of ARF protein signal transduction
3,572.03 10.45 5,462 52,003
brain development
2,427.71 7.11 5,453 76,389
presynapse
1,885.74 5.53 5,467 98,596
postsynapse
731.05 2.00 1,308 60,849
small GTPase binding
640.00 1.88 5,463 290,296
regulation of clathrin coat assembly
18,312.46 1.69 98 182
regulation of endosome size
14,170.36 1.54 90 216
cytoplasmic side of early endosome membrane
8,897.67 1.50 90 344
Totals 52109 3733347
No co-occurrence statistics for GO:0036465 based on MANUAL annotations
The top 100 of 419 co-occurring terms
Co-occurring Term PR S% #Together #Compared
synaptic vesicle recycling
11,637.83 100.00 111 111
regulation of ARF protein signal transduction
6,382.04 33.33 51 93
synaptic vesicle coating
10,861.97 12.50 14 15
regulation of G protein-coupled receptor signaling pathway
1,644.13 12.11 51 361
clathrin-coated vesicle cargo loading, AP-3-mediated
7,405.89 11.76 14 22
regulation of clathrin coat assembly
8,728.37 7.89 9 12
AP-2 adaptor complex binding
1,533.67 7.62 17 129
synaptic vesicle budding from endosome
2,053.73 5.88 9 51
plasma membrane organization
724.70 4.63 17 273
presynaptic active zone membrane
628.07 4.16 17 315
Totals 861 23952

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2020-03-15 Added RELATION is a GO:0051649 (establishment of localization in cell)
2019-08-30 Deleted RELATION is a GO:0051649 (establishment of localization in cell)
2017-12-13 Deleted RELATION is a GO:0048489 (synaptic vesicle transport)
2017-12-13 Added RELATION is a GO:0006810 (transport)
2017-12-13 Added RELATION is a GO:0051649 (establishment of localization in cell)
2016-11-28 Deleted RELATION is a GO:0099003 (vesicle-mediated transport in synapse)
2016-06-22 Added RELATION is a GO:0099003 (vesicle-mediated transport in synapse)
2016-06-22 Deleted SUBSET goslim_synapse
2016-06-11 Deleted DEFINITION The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane.
Timestamp Action Category Detail
2014-06-28 Added TERM synaptic vesicle recycling
Timestamp Action Category Detail
2016-06-11 Deleted DEFINITION The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane.
2016-06-11 Added DEFINITION The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane.
2014-06-28 Added DEFINITION The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane.
2014-06-28 Added SYNONYM kiss-and-run synaptic vesicle recycling
2014-06-28 Added SYNONYM kiss-and-stay synaptic vesicle recycling
Timestamp Action Category Detail
2020-03-15 Added RELATION is a GO:0051649 (establishment of localization in cell)
2019-08-30 Deleted RELATION is a GO:0051649 (establishment of localization in cell)
2017-12-13 Deleted RELATION is a GO:0048489 (synaptic vesicle transport)
2017-12-13 Added RELATION is a GO:0006810 (transport)
2017-12-13 Added RELATION is a GO:0051649 (establishment of localization in cell)
2016-11-28 Deleted RELATION is a GO:0099003 (vesicle-mediated transport in synapse)
2016-06-22 Added RELATION is a GO:0099003 (vesicle-mediated transport in synapse)
2016-01-20 Added RELATION part of GO:0099504 (synaptic vesicle cycle)
2014-06-28 Added RELATION is a GO:0048489 (synaptic vesicle transport)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:33208 (Metazoa)
2016-06-22 Deleted SUBSET goslim_synapse
2014-12-13 Added SUBSET goslim_synapse
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