GO:0036465
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synaptic vesicle recycling
Biological Process
Definition (GO:0036465 GONUTS page)
The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane. PMID:15217342 PMID:22026965 PMID:23245563
Acknowledgement
This term was created by the GO Consortium with support from:
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
kiss-and-stay synaptic vesicle recycling | narrow |
kiss-and-run synaptic vesicle recycling | narrow |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0036465
Child Term | Relationship to GO:0036465 |
---|---|
regulation of synaptic vesicle recycling
|
regulates |
positive regulation of synaptic vesicle recycling
|
positively_regulates |
synaptic vesicle recycling via endosome
|
is_a |
synaptic vesicle endocytosis
|
part_of |
negative regulation of synaptic vesicle recycling
|
negatively_regulates |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0036465 | synaptic vesicle recycling | Only in Taxon | 33208 | Metazoa |
More information on taxon constraints in GO is available here
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0036465 based on ALL annotations
The top 100 of 673 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
synaptic vesicle recycling
|
34,008.86 | 100.00 | 5,732 | 5,732 |
regulation of G protein-coupled receptor signaling pathway
|
5,889.36 | 17.17 | 5,462 | 31,541 |
regulation of ARF protein signal transduction
|
3,572.03 | 10.45 | 5,462 | 52,003 |
brain development
|
2,427.71 | 7.11 | 5,453 | 76,389 |
presynapse
|
1,885.74 | 5.53 | 5,467 | 98,596 |
postsynapse
|
731.05 | 2.00 | 1,308 | 60,849 |
small GTPase binding
|
640.00 | 1.88 | 5,463 | 290,296 |
regulation of clathrin coat assembly
|
18,312.46 | 1.69 | 98 | 182 |
regulation of endosome size
|
14,170.36 | 1.54 | 90 | 216 |
cytoplasmic side of early endosome membrane
|
8,897.67 | 1.50 | 90 | 344 |
Totals | 52109 | 3733347 |
No co-occurrence statistics for GO:0036465 based on MANUAL annotations
The top 100 of 419 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
synaptic vesicle recycling
|
11,637.83 | 100.00 | 111 | 111 |
regulation of ARF protein signal transduction
|
6,382.04 | 33.33 | 51 | 93 |
synaptic vesicle coating
|
10,861.97 | 12.50 | 14 | 15 |
regulation of G protein-coupled receptor signaling pathway
|
1,644.13 | 12.11 | 51 | 361 |
clathrin-coated vesicle cargo loading, AP-3-mediated
|
7,405.89 | 11.76 | 14 | 22 |
regulation of clathrin coat assembly
|
8,728.37 | 7.89 | 9 | 12 |
AP-2 adaptor complex binding
|
1,533.67 | 7.62 | 17 | 129 |
synaptic vesicle budding from endosome
|
2,053.73 | 5.88 | 9 | 51 |
plasma membrane organization
|
724.70 | 4.63 | 17 | 273 |
presynaptic active zone membrane
|
628.07 | 4.16 | 17 | 315 |
Totals | 861 | 23952 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:33208 (Metazoa) |
2020-03-15 | Added | RELATION | is a GO:0051649 (establishment of localization in cell) |
2019-08-30 | Deleted | RELATION | is a GO:0051649 (establishment of localization in cell) |
2017-12-13 | Deleted | RELATION | is a GO:0048489 (synaptic vesicle transport) |
2017-12-13 | Added | RELATION | is a GO:0006810 (transport) |
2017-12-13 | Added | RELATION | is a GO:0051649 (establishment of localization in cell) |
2016-11-28 | Deleted | RELATION | is a GO:0099003 (vesicle-mediated transport in synapse) |
2016-06-22 | Added | RELATION | is a GO:0099003 (vesicle-mediated transport in synapse) |
2016-06-22 | Deleted | SUBSET | goslim_synapse |
2016-06-11 | Deleted | DEFINITION | The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2014-06-28 | Added | TERM | synaptic vesicle recycling |
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-06-11 | Deleted | DEFINITION | The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. |
2016-06-11 | Added | DEFINITION | The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane. |
2014-06-28 | Added | DEFINITION | The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. |
2014-06-28 | Added | SYNONYM | kiss-and-run synaptic vesicle recycling |
2014-06-28 | Added | SYNONYM | kiss-and-stay synaptic vesicle recycling |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-03-15 | Added | RELATION | is a GO:0051649 (establishment of localization in cell) |
2019-08-30 | Deleted | RELATION | is a GO:0051649 (establishment of localization in cell) |
2017-12-13 | Deleted | RELATION | is a GO:0048489 (synaptic vesicle transport) |
2017-12-13 | Added | RELATION | is a GO:0006810 (transport) |
2017-12-13 | Added | RELATION | is a GO:0051649 (establishment of localization in cell) |
2016-11-28 | Deleted | RELATION | is a GO:0099003 (vesicle-mediated transport in synapse) |
2016-06-22 | Added | RELATION | is a GO:0099003 (vesicle-mediated transport in synapse) |
2016-01-20 | Added | RELATION | part of GO:0099504 (synaptic vesicle cycle) |
2014-06-28 | Added | RELATION | is a GO:0048489 (synaptic vesicle transport) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:33208 (Metazoa) |
2016-06-22 | Deleted | SUBSET | goslim_synapse |
2014-12-13 | Added | SUBSET | goslim_synapse |
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