This term is obsolete.

GO:0038020 JSON

insulin receptor recycling

Biological Process

Definition (GO:0038020 GONUTS page)

The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation. PMID:3907718

347 annotations

Ancestor Chart

Ancestor chart for GO:0038020
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Ancestor chart

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:

Ontology Development Project
signalling Link

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0038020 insulin receptor recycling Only in Taxon 6072 Eumetazoa

More information on taxon constraints in GO is available here

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0038020 based on ALL annotations
The top 100 of 235 co-occurring terms
Co-occurring Term PR S% #Together #Compared
insulin receptor recycling
571,668.00 100.00 341 341
endosome lumen
386,807.97 54.13 249 368
regulation of hepatocyte growth factor receptor signaling pathway
536,732.75 48.01 169 180
positive regulation of early endosome to recycling endosome transport
571,668.00 26.69 91 91
negative regulation of neurofibrillary tangle assembly
565,097.10 25.15 86 87
negative regulation of positive thymic T cell selection
571,668.00 23.46 80 80
negative regulation of interleukin-2-mediated signaling pathway
525,671.75 22.99 80 87
negative regulation of interleukin-6-mediated signaling pathway
513,858.88 22.86 80 89
positive regulation of glial cell-derived neurotrophic factor production
265,417.28 20.40 91 196
negative regulation of chemotaxis
317,593.34 19.75 80 144
Totals 7591 518401
No co-occurrence statistics for GO:0038020 based on MANUAL annotations
The top 100 of 199 co-occurring terms
Co-occurring Term PR S% #Together #Compared
insulin receptor recycling
107,649.92 100.00 12 12
endosome lumen
31,896.27 25.81 8 27
positive regulation of early endosome to recycling endosome transport
107,649.92 25.00 3 3
negative regulation of neurofibrillary tangle assembly
80,737.44 23.08 3 4
regulation of hepatocyte growth factor receptor signaling pathway
64,589.95 21.43 3 5
positive regulation of glial cell-derived neurotrophic factor production
64,589.95 21.43 3 5
insulin catabolic process
28,706.65 17.39 4 15
negative regulation of interleukin-2-mediated signaling pathway
71,766.62 15.38 2 3
negative regulation of positive thymic T cell selection
71,766.62 15.38 2 3
negative regulation of interleukin-4-mediated signaling pathway
53,824.96 14.29 2 4
Totals 226 9663

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:6072 (Eumetazoa)
2011-06-26 Added RELATION is a GO:0001881 (receptor recycling)
2011-06-26 Added DEFINITION The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.
2011-06-26 Added TERM insulin receptor recycling
2011-06-26 Added RELATION part of GO:0046628 (positive regulation of insulin receptor signaling pathway)
Timestamp Action Category Detail
2011-06-26 Added TERM insulin receptor recycling
Timestamp Action Category Detail
2011-06-26 Added DEFINITION The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.
Timestamp Action Category Detail
2011-06-26 Added RELATION is a GO:0001881 (receptor recycling)
2011-06-26 Added RELATION part of GO:0046628 (positive regulation of insulin receptor signaling pathway)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:6072 (Eumetazoa)
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