GO:0038020
JSON
insulin receptor recycling
Biological Process
Definition (GO:0038020 GONUTS page)
The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation. PMID:3907718
Ancestor Chart
GO Discussions
The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:
Ontology Development Project | |
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signalling | Link |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0038020 | insulin receptor recycling | Only in Taxon | 6072 | Eumetazoa |
More information on taxon constraints in GO is available here
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0038020 based on ALL annotations
The top 100 of 235 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
insulin receptor recycling
|
571,668.00 | 100.00 | 341 | 341 |
endosome lumen
|
386,807.97 | 54.13 | 249 | 368 |
regulation of hepatocyte growth factor receptor signaling pathway
|
536,732.75 | 48.01 | 169 | 180 |
positive regulation of early endosome to recycling endosome transport
|
571,668.00 | 26.69 | 91 | 91 |
negative regulation of neurofibrillary tangle assembly
|
565,097.10 | 25.15 | 86 | 87 |
negative regulation of positive thymic T cell selection
|
571,668.00 | 23.46 | 80 | 80 |
negative regulation of interleukin-2-mediated signaling pathway
|
525,671.75 | 22.99 | 80 | 87 |
negative regulation of interleukin-6-mediated signaling pathway
|
513,858.88 | 22.86 | 80 | 89 |
positive regulation of glial cell-derived neurotrophic factor production
|
265,417.28 | 20.40 | 91 | 196 |
negative regulation of chemotaxis
|
317,593.34 | 19.75 | 80 | 144 |
Totals | 7591 | 518401 |
No co-occurrence statistics for GO:0038020 based on MANUAL annotations
The top 100 of 199 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
insulin receptor recycling
|
107,649.92 | 100.00 | 12 | 12 |
endosome lumen
|
31,896.27 | 25.81 | 8 | 27 |
positive regulation of early endosome to recycling endosome transport
|
107,649.92 | 25.00 | 3 | 3 |
negative regulation of neurofibrillary tangle assembly
|
80,737.44 | 23.08 | 3 | 4 |
regulation of hepatocyte growth factor receptor signaling pathway
|
64,589.95 | 21.43 | 3 | 5 |
positive regulation of glial cell-derived neurotrophic factor production
|
64,589.95 | 21.43 | 3 | 5 |
insulin catabolic process
|
28,706.65 | 17.39 | 4 | 15 |
negative regulation of interleukin-2-mediated signaling pathway
|
71,766.62 | 15.38 | 2 | 3 |
negative regulation of positive thymic T cell selection
|
71,766.62 | 15.38 | 2 | 3 |
negative regulation of interleukin-4-mediated signaling pathway
|
53,824.96 | 14.29 | 2 | 4 |
Totals | 226 | 9663 |
Change Log
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Timestamp | Action | Category | Detail |
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2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:6072 (Eumetazoa) |
2011-06-26 | Added | RELATION | is a GO:0001881 (receptor recycling) |
2011-06-26 | Added | DEFINITION | The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation. |
2011-06-26 | Added | TERM | insulin receptor recycling |
2011-06-26 | Added | RELATION | part of GO:0046628 (positive regulation of insulin receptor signaling pathway) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-06-26 | Added | TERM | insulin receptor recycling |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-06-26 | Added | DEFINITION | The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-06-26 | Added | RELATION | is a GO:0001881 (receptor recycling) |
2011-06-26 | Added | RELATION | part of GO:0046628 (positive regulation of insulin receptor signaling pathway) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:6072 (Eumetazoa) |
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