GO:0038095
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Fc-epsilon receptor signaling pathway
Biological Process
Definition (GO:0038095 GONUTS page)
The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. PMID:12413516 PMID:15048725
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
Fc-epsilon receptor signalling pathway | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0038095
Child Term | Relationship to GO:0038095 |
---|---|
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway
|
is_a |
IgE receptor activity
|
part_of |
GO Discussions
The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:
Ontology Development Project | |
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signalling | Link |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0038095 | Fc-epsilon receptor signaling pathway | Never in Taxon | 4751 | Fungi |
More information on taxon constraints in GO is available here
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0038095 based on ALL annotations
The top 100 of 675 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
Fc-epsilon receptor signaling pathway
|
239,482.53 | 100.00 | 814 | 814 |
IgE receptor activity
|
239,482.55 | 65.48 | 533 | 533 |
Fc-epsilon receptor I complex
|
198,643.62 | 54.63 | 501 | 604 |
high-affinity IgE receptor activity
|
239,482.52 | 14.99 | 122 | 122 |
Fc receptor mediated stimulatory signaling pathway
|
128,173.76 | 12.49 | 114 | 213 |
T cell differentiation involved in immune response
|
92,994.94 | 11.39 | 113 | 291 |
Fc receptor-mediated immune complex endocytosis
|
141,361.22 | 9.74 | 85 | 144 |
response to platelet-derived growth factor
|
110,638.13 | 8.72 | 79 | 171 |
Fc-gamma receptor signaling pathway
|
29,465.65 | 7.94 | 149 | 1,211 |
IgE binding
|
22,107.24 | 7.93 | 293 | 3,174 |
Totals | 8011 | 722318 |
No co-occurrence statistics for GO:0038095 based on MANUAL annotations
The top 100 of 435 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
Fc-epsilon receptor signaling pathway
|
32,294.98 | 100.00 | 40 | 40 |
Fc-gamma receptor signaling pathway involved in phagocytosis
|
5,568.10 | 7.81 | 5 | 29 |
response to platelet-derived growth factor
|
10,764.99 | 6.52 | 3 | 9 |
diapedesis
|
8,073.74 | 6.12 | 3 | 12 |
negative regulation of mast cell activation involved in immune response
|
7,452.69 | 6.00 | 3 | 13 |
extracellular matrix-cell signaling
|
6,920.35 | 5.88 | 3 | 14 |
Fc-epsilon receptor I complex
|
4,212.39 | 5.00 | 3 | 23 |
regulation of platelet aggregation
|
4,036.87 | 4.92 | 3 | 24 |
Fc receptor mediated stimulatory signaling pathway
|
3,588.33 | 4.69 | 3 | 27 |
interleukin-3-mediated signaling pathway
|
3,340.86 | 4.55 | 3 | 29 |
Totals | 267 | 5266 |
Change Log
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Timestamp | Action | Category | Detail |
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2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2022-03-14 | Deleted | DEFINITION | A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. |
2022-03-14 | Added | DEFINITION | The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. |
2012-02-19 | Added | TERM | Fc-epsilon receptor signaling pathway |
2012-02-19 | Added | SYNONYM | Fc-epsilon receptor signalling pathway |
2012-02-19 | Added | DEFINITION | A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. |
2012-02-19 | Added | RELATION | is a GO:0038093 (Fc receptor signaling pathway) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-02-19 | Added | TERM | Fc-epsilon receptor signaling pathway |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-03-14 | Deleted | DEFINITION | A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. |
2022-03-14 | Added | DEFINITION | The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. |
2012-02-19 | Added | SYNONYM | Fc-epsilon receptor signalling pathway |
2012-02-19 | Added | DEFINITION | A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-02-19 | Added | RELATION | is a GO:0038093 (Fc receptor signaling pathway) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
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