This term is obsolete.

GO:0038095 JSON

Fc-epsilon receptor signaling pathway

Biological Process

Definition (GO:0038095 GONUTS page)

The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region. PMID:12413516 PMID:15048725

1,604 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
Fc-epsilon receptor signalling pathway exact

Ancestor Chart

Ancestor chart for GO:0038095
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0038095

Child Term Relationship to
GO:0038095
positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway
is_a
IgE receptor activity
part_of

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:

Ontology Development Project
signalling Link

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0038095 Fc-epsilon receptor signaling pathway Never in Taxon 4751 Fungi

More information on taxon constraints in GO is available here

Cross-references

Database ID Description
Reactome R-HSA-2454202

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0038095 based on ALL annotations
The top 100 of 673 co-occurring terms
Co-occurring Term PR S% #Together #Compared
237,595.75 100.00 834 834
237,595.77 65.71 548 548
197,740.98 55.01 516 620
237,595.77 14.99 125 125
126,427.12 12.39 116 218
93,254.31 11.36 115 293
140,247.50 9.52 85 144
110,412.15 8.54 79 170
22,599.47 8.13 300 3,154
29,263.43 7.91 151 1,226
Totals 8359 880598
No co-occurrence statistics for GO:0038095 based on MANUAL annotations
The top 100 of 435 co-occurring terms
Co-occurring Term PR S% #Together #Compared
33,607.93 100.00 42 42
4,200.99 6.49 5 40
11,202.64 6.25 3 9
8,401.98 5.88 3 12
7,755.68 5.77 3 13
7,201.70 5.66 3 14
4,200.99 4.76 3 24
4,200.99 4.76 3 24
3,252.38 4.29 3 31
8,401.98 4.17 2 8
Totals 291 6884

Change Log

Timestamp Action Category Detail
2024-12-05 Added XREF Reactome:R-HSA-2454202
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2022-03-14 Deleted DEFINITION A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.
2022-03-14 Added DEFINITION The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.
2012-02-19 Added DEFINITION A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.
2012-02-19 Added SYNONYM Fc-epsilon receptor signalling pathway
2012-02-19 Added RELATION is a GO:0038093 (Fc receptor signaling pathway)
2012-02-19 Added TERM Fc-epsilon receptor signaling pathway
Timestamp Action Category Detail
2012-02-19 Added TERM Fc-epsilon receptor signaling pathway
Timestamp Action Category Detail
2022-03-14 Deleted DEFINITION A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.
2022-03-14 Added DEFINITION The series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.
2012-02-19 Added DEFINITION A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.
2012-02-19 Added SYNONYM Fc-epsilon receptor signalling pathway
Timestamp Action Category Detail
2012-02-19 Added RELATION is a GO:0038093 (Fc receptor signaling pathway)
Timestamp Action Category Detail
2024-12-05 Added XREF Reactome:R-HSA-2454202
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
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