This term is obsolete.

GO:0038165 JSON

oncostatin-M-mediated signaling pathway

Biological Process

Definition (GO:0038165 GONUTS page)

The series of molecular signals initiated by oncostatin-M (OSM) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways. PMID:10579456 PMID:12811586

1,448 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
oncostatin-M signaling pathway exact
OSM signaling pathway exact

Ancestor Chart

Ancestor chart for GO:0038165
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0038165

Child Term Relationship to
GO:0038165
oncostatin-M receptor activity
part_of

GO Discussions

The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:

Ontology Development Project
signalling Link

Cross-references

Database ID Description
InterPro IPR039578 Oncostatin-M

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0038165 based on ALL annotations
The top 100 of 102 co-occurring terms
Co-occurring Term PR S% #Together #Compared
oncostatin-M-mediated signaling pathway
246,768.20 100.00 803 803
oncostatin-M receptor activity
246,768.19 76.96 618 618
ciliary neurotrophic factor receptor binding
68,885.82 24.79 553 1,981
leukemia inhibitory factor receptor activity
246,768.19 23.91 192 192
oncostatin-M receptor binding
241,545.58 22.92 185 189
oncostatin-M receptor complex
246,768.20 21.30 171 171
leukemia inhibitory factor signaling pathway
53,596.72 12.84 192 884
ciliary neurotrophic factor receptor activity
52,410.95 12.67 192 904
interleukin-6 receptor activity
95,622.68 9.79 93 240
interleukin-6 binding
78,325.74 9.27 93 293
Totals 12368 85602552
No co-occurrence statistics for GO:0038165 based on MANUAL annotations
The top 88 of 88 co-occurring terms
Co-occurring Term PR S% #Together #Compared
oncostatin-M-mediated signaling pathway
176,441.62 100.00 8 8
oncostatin-M receptor complex
176,441.62 50.00 4 4
leukemia inhibitory factor receptor activity
141,153.30 44.44 4 5
oncostatin-M receptor binding
58,813.88 16.67 2 6
oncostatin-M receptor activity
30,247.14 16.22 6 35
ciliary neurotrophic factor receptor activity
32,080.30 15.38 4 22
leukemia inhibitory factor signaling pathway
30,685.50 14.81 4 23
positive regulation of acute inflammatory response
20,358.65 9.68 3 26
ciliary neurotrophic factor receptor binding
16,803.97 9.23 6 63
interleukin-11-mediated signaling pathway
20,757.84 8.70 2 17
Totals 201 407845

Change Log

Timestamp Action Category Detail
2022-03-14 Deleted DEFINITION A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways.
2022-03-14 Added DEFINITION The series of molecular signals initiated by oncostatin-M (OSM) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways.
2012-05-15 Added SYNONYM oncostatin-M signaling pathway
2012-05-15 Added DEFINITION A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways.
2012-05-15 Added RELATION is a GO:0019221 (cytokine-mediated signaling pathway)
2012-05-15 Added SYNONYM OSM signaling pathway
2012-05-15 Added TERM oncostatin-M-mediated signaling pathway
Timestamp Action Category Detail
2012-05-15 Added TERM oncostatin-M-mediated signaling pathway
Timestamp Action Category Detail
2022-03-14 Deleted DEFINITION A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways.
2022-03-14 Added DEFINITION The series of molecular signals initiated by oncostatin-M (OSM) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways.
2012-05-15 Added SYNONYM oncostatin-M signaling pathway
2012-05-15 Added DEFINITION A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways.
2012-05-15 Added SYNONYM OSM signaling pathway
Timestamp Action Category Detail
2012-05-15 Added RELATION is a GO:0019221 (cytokine-mediated signaling pathway)
Timestamp Action Category Detail
Timestamp Action Category Detail
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