GO:0038165
JSON
oncostatin-M-mediated signaling pathway
Biological Process
Definition (GO:0038165 GONUTS page)
The series of molecular signals initiated by oncostatin-M (OSM) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways. PMID:10579456 PMID:12811586
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
oncostatin-M signaling pathway | exact |
OSM signaling pathway | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0038165
Child Term | Relationship to GO:0038165 |
---|---|
oncostatin-M receptor activity
|
part_of |
GO Discussions
The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:
Ontology Development Project | |
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signalling | Link |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR039578 | Oncostatin-M |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0038165 based on ALL annotations
The top 100 of 102 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
oncostatin-M-mediated signaling pathway
|
246,768.20 | 100.00 | 803 | 803 |
oncostatin-M receptor activity
|
246,768.19 | 76.96 | 618 | 618 |
ciliary neurotrophic factor receptor binding
|
68,885.82 | 24.79 | 553 | 1,981 |
leukemia inhibitory factor receptor activity
|
246,768.19 | 23.91 | 192 | 192 |
oncostatin-M receptor binding
|
241,545.58 | 22.92 | 185 | 189 |
oncostatin-M receptor complex
|
246,768.20 | 21.30 | 171 | 171 |
leukemia inhibitory factor signaling pathway
|
53,596.72 | 12.84 | 192 | 884 |
ciliary neurotrophic factor receptor activity
|
52,410.95 | 12.67 | 192 | 904 |
interleukin-6 receptor activity
|
95,622.68 | 9.79 | 93 | 240 |
interleukin-6 binding
|
78,325.74 | 9.27 | 93 | 293 |
Totals | 12368 | 85602552 |
No co-occurrence statistics for GO:0038165 based on MANUAL annotations
The top 88 of 88 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
oncostatin-M-mediated signaling pathway
|
176,441.62 | 100.00 | 8 | 8 |
oncostatin-M receptor complex
|
176,441.62 | 50.00 | 4 | 4 |
leukemia inhibitory factor receptor activity
|
141,153.30 | 44.44 | 4 | 5 |
oncostatin-M receptor binding
|
58,813.88 | 16.67 | 2 | 6 |
oncostatin-M receptor activity
|
30,247.14 | 16.22 | 6 | 35 |
ciliary neurotrophic factor receptor activity
|
32,080.30 | 15.38 | 4 | 22 |
leukemia inhibitory factor signaling pathway
|
30,685.50 | 14.81 | 4 | 23 |
positive regulation of acute inflammatory response
|
20,358.65 | 9.68 | 3 | 26 |
ciliary neurotrophic factor receptor binding
|
16,803.97 | 9.23 | 6 | 63 |
interleukin-11-mediated signaling pathway
|
20,757.84 | 8.70 | 2 | 17 |
Totals | 201 | 407845 |
Change Log
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Timestamp | Action | Category | Detail |
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2022-03-14 | Deleted | DEFINITION | A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways. |
2022-03-14 | Added | DEFINITION | The series of molecular signals initiated by oncostatin-M (OSM) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways. |
2012-05-15 | Added | SYNONYM | oncostatin-M signaling pathway |
2012-05-15 | Added | DEFINITION | A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways. |
2012-05-15 | Added | RELATION | is a GO:0019221 (cytokine-mediated signaling pathway) |
2012-05-15 | Added | SYNONYM | OSM signaling pathway |
2012-05-15 | Added | TERM | oncostatin-M-mediated signaling pathway |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-05-15 | Added | TERM | oncostatin-M-mediated signaling pathway |
Timestamp | Action | Category | Detail |
---|---|---|---|
2022-03-14 | Deleted | DEFINITION | A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways. |
2022-03-14 | Added | DEFINITION | The series of molecular signals initiated by oncostatin-M (OSM) binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways. |
2012-05-15 | Added | SYNONYM | oncostatin-M signaling pathway |
2012-05-15 | Added | DEFINITION | A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways. |
2012-05-15 | Added | SYNONYM | OSM signaling pathway |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-05-15 | Added | RELATION | is a GO:0019221 (cytokine-mediated signaling pathway) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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