GO:0042011
JSON
interleukin-16 binding
Molecular Function
Definition (GO:0042011 GONUTS page)
Binding to interleukin-16.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| IL-16 binding | exact |
Ancestor Chart
Ancestor chart for GO:0042011
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
| Binding term considerations | Link |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
| Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
|---|---|---|---|---|---|
| GO:0042011 | interleukin-16 binding | Never in Taxon | 4751 | Fungi |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| NOT-qualified manual | protein | P21333-1 | 9606 | FLNA_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 | |
| NOT-qualified manual | protein | P63026 | 9913 | VAMP2_BOVIN | GO:0005515 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699 | |
| NOT-qualified manual | protein | Q86V48 | 9606 | LUZP1_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0042011 based on ALL annotations
The top 68 of 68 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
interleukin-16 binding
|
2,957,535.20 | 100.00 | 67 | 67 |
|
interleukin-16 receptor activity
|
2,914,042.20 | 98.53 | 67 | 68 |
|
T cell selection
|
2,476,935.80 | 83.75 | 67 | 80 |
|
helper T cell enhancement of adaptive immune response
|
2,890,318.50 | 63.24 | 43 | 44 |
|
maintenance of protein location in cell
|
297,529.80 | 10.06 | 67 | 666 |
|
cellular response to granulocyte macrophage colony-stimulating factor stimulus
|
285,937.75 | 9.67 | 67 | 693 |
|
MHC class II protein complex binding
|
274,452.72 | 9.28 | 67 | 722 |
|
positive regulation of viral entry into host cell
|
219,927.70 | 7.44 | 67 | 901 |
|
positive regulation of monocyte differentiation
|
135,074.89 | 4.57 | 67 | 1,467 |
|
regulation of T cell activation
|
105,795.45 | 3.58 | 67 | 1,873 |
| Totals | 2625 | 92378385 | ||
No co-occurrence statistics for GO:0042011 based on MANUAL annotations
The top 63 of 63 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
interleukin-16 binding
|
705,766.50 | 100.00 | 2 | 2 |
|
interleukin-16 receptor activity
|
470,511.00 | 66.67 | 2 | 3 |
|
helper T cell enhancement of adaptive immune response
|
352,883.25 | 33.33 | 1 | 2 |
|
T cell selection
|
78,418.50 | 11.11 | 2 | 18 |
|
cellular response to ionomycin
|
70,576.65 | 9.09 | 1 | 10 |
|
response to methamphetamine hydrochloride
|
64,160.59 | 8.33 | 1 | 11 |
|
maintenance of protein location in cell
|
36,193.16 | 5.13 | 2 | 39 |
|
positive regulation of viral entry into host cell
|
33,607.93 | 4.76 | 2 | 42 |
|
MHC class II protein binding
|
32,826.35 | 4.65 | 2 | 43 |
|
immunoglobulin binding
|
33,607.93 | 4.55 | 1 | 21 |
| Totals | 93 | 323125 | ||
Change Log
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
| 2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with interleukin-16. |
| 2021-05-24 | Added | DEFINITION | Binding to interleukin-16. |
| 2011-10-28 | Added | RELATION | has part GO:0042012 (interleukin-16 receptor activity) |
| 2009-07-03 | Deleted | DEFINITION | Interacting selectively with interleukin-16. |
| 2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with interleukin-16. |
| 2008-11-13 | Deleted | RELATION | is a GO:0019965 (interleukin binding) |
| 2008-11-13 | Added | RELATION | is a GO:0019955 (cytokine binding) |
| 2008-05-13 | Added | DEFINITION | Interacting selectively with interleukin-16. |
| 2008-05-12 | Deleted | DEFINITION | Interacting selectively with interleukin-16. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2003-06-10 | Updated | TERM | interleukin-16 binding |
| 2003-03-19 | Updated | TERM | interleukin-16 binding activity |
| 2002-01-29 | Added | TERM | interleukin-16 binding |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with interleukin-16. |
| 2021-05-24 | Added | DEFINITION | Binding to interleukin-16. |
| 2009-07-03 | Deleted | DEFINITION | Interacting selectively with interleukin-16. |
| 2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with interleukin-16. |
| 2008-05-13 | Added | DEFINITION | Interacting selectively with interleukin-16. |
| 2008-05-12 | Deleted | DEFINITION | Interacting selectively with interleukin-16. |
| 2007-08-09 | Deleted | SYNONYM | IL-16 binding |
| 2007-08-09 | Added | SYNONYM | IL-16 binding |
| 2004-04-19 | Added | SYNONYM | IL-16 binding |
| 2004-04-16 | Deleted | SYNONYM | IL-16 binding |
| 2003-03-26 | Updated | DEFINITION | Interacting selectively with interleukin-16. |
| 2002-11-27 | Added | DEFINITION | Interacting selectively and stoichiometrically with interleukin-16. |
| 2002-08-24 | Added | SYNONYM | IL-16 binding |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2011-10-28 | Added | RELATION | has part GO:0042012 (interleukin-16 receptor activity) |
| 2008-11-13 | Deleted | RELATION | is a GO:0019965 (interleukin binding) |
| 2008-11-13 | Added | RELATION | is a GO:0019955 (cytokine binding) |
| 2008-04-01 | Updated | RELATION | is a GO:0019965 (interleukin binding) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
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