This term is obsolete.

GO:0042092 JSON

type 2 immune response

Biological Process

Definition (GO:0042092 GONUTS page)

An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects. PMID:18000958 PMID:18007680 PMID:20065995 PMID:20200518

1,080 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
T-helper 2 type immune response narrow
Th2 immune response narrow

Ancestor Chart

Ancestor chart for GO:0042092
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0042092

Child Term Relationship to
GO:0042092
T-helper 2 cell cytokine production
part_of
negative regulation of type 2 immune response
negatively_regulates
regulation of type 2 immune response
regulates
positive regulation of type 2 immune response
positively_regulates
T-helper 2 cell differentiation
part_of

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0042092 type 2 immune response Never in Taxon 4895 Schizosaccharomyces

More information on taxon constraints in GO is available here

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0042092 based on ALL annotations
The top 100 of 356 co-occurring terms
Co-occurring Term PR S% #Together #Compared
717,952.44 100.00 276 276
710,314.60 33.57 93 94
710,232.50 33.21 92 93
403,294.25 26.22 91 162
388,195.20 26.20 93 172
717,952.40 25.36 70 70
717,952.40 25.36 70 70
373,335.25 25.28 91 175
644,316.25 24.65 70 78
591,254.90 24.05 70 85
Totals 6106 205123
No co-occurrence statistics for GO:0042092 based on MANUAL annotations
The top 100 of 316 co-occurring terms
Co-occurring Term PR S% #Together #Compared
32,826.35 100.00 43 43
32,826.35 13.95 6 6
32,826.35 13.95 6 6
14,068.44 11.76 6 14
14,068.44 11.76 6 14
27,355.29 11.36 5 6
12,309.88 11.32 6 16
11,585.77 11.11 6 17
9,847.91 10.53 6 20
12,625.52 9.80 5 13
Totals 476 8063

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
2011-03-06 Deleted RELATION is a GO:0002460 (adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains)
2011-03-06 Added RELATION is a GO:0006955 (immune response)
2010-10-11 Updated TERM type 2 immune response
2010-10-11 Deleted SYNONYM Th2 immune response
2010-10-11 Added SYNONYM Th2 immune response
2010-10-11 Added DEFINITION An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.
2010-10-11 Deleted DEFINITION An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is typically orchestrated by the production of particular cytokines by T-helper 2 cells, most notably IL-4, IL-5, IL-10, and IL-13, resulting in enhanced production of certain antibody isotypes and other effects.
2010-10-11 Added SYNONYM T-helper 2 type immune response
2008-05-13 Added DEFINITION An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is typically orchestrated by the production of particular cytokines by T-helper 2 cells, most notably IL-4, IL-5, IL-10, and IL-13, resulting in enhanced production of certain antibody isotypes and other effects.
Timestamp Action Category Detail
2010-10-11 Updated TERM type 2 immune response
2002-02-19 Added TERM T-helper 2 type immune response
Timestamp Action Category Detail
2010-10-11 Deleted SYNONYM Th2 immune response
2010-10-11 Added SYNONYM Th2 immune response
2010-10-11 Added DEFINITION An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.
2010-10-11 Deleted DEFINITION An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is typically orchestrated by the production of particular cytokines by T-helper 2 cells, most notably IL-4, IL-5, IL-10, and IL-13, resulting in enhanced production of certain antibody isotypes and other effects.
2010-10-11 Added SYNONYM T-helper 2 type immune response
2008-05-13 Added DEFINITION An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is typically orchestrated by the production of particular cytokines by T-helper 2 cells, most notably IL-4, IL-5, IL-10, and IL-13, resulting in enhanced production of certain antibody isotypes and other effects.
2008-05-12 Deleted DEFINITION An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is typically orchestrated by the production of particular cytokines by T-helper 2 cells, most notably IL-4, IL-5, IL-10, and IL-13, resulting in enhanced production of certain antibody isotypes and other effects.
2007-08-09 Deleted SYNONYM Th2 immune response
2007-08-09 Added SYNONYM Th2 immune response
2006-09-21 Added SYNONYM Th2 immune response
2006-09-19 Added DEFINITION An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is typically orchestrated by the production of particular cytokines by T-helper 2 cells, most notably IL-4, IL-5, IL-10, and IL-13, resulting in enhanced production of certain antibody isotypes and other effects.
Timestamp Action Category Detail
2011-03-06 Deleted RELATION is a GO:0002460 (adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains)
2011-03-06 Added RELATION is a GO:0006955 (immune response)
2008-04-01 Updated RELATION is a GO:0002460 (adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
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