This term is obsolete.

GO:0042254 JSON

ribosome biogenesis

Biological Process

Definition (GO:0042254 GONUTS page)

A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis. PMID:26404467

Secondary IDs

GO:0007046

4,648,013 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
ribosome biogenesis and assembly exact

Ancestor Chart

Ancestor chart for GO:0042254
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0042254

Child Term Relationship to
GO:0042254
regulation of ribosome biogenesis
regulates
ribosomal subunit export from nucleus
part_of
ribosomal large subunit biogenesis
part_of
positive regulation of ribosome biogenesis
positively_regulates
rRNA processing
part_of
negative regulation of ribosome biogenesis
negatively_regulates
ribosome assembly
part_of
ribosomal small subunit biogenesis
part_of

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein Q6MG08 10116 ABCF1_RAT GO:0042254 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q6P542 10090 ABCF1_MOUSE GO:0042254 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q767L0 9823 ABCF1_PIG GO:0042254 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q7YR37 9598 ABCF1_PANTR GO:0042254 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein Q8NE71-2 9606 ABCF1_HUMAN GO:0042254 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:19570978

Cross-references

Database ID Description
InterPro IPR004037 Large ribosomal subunit protein eL8-like, conserved site
InterPro IPR007023 Ribosomal biogenesis regulatory protein
InterPro IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10
InterPro IPR007504 H/ACA ribonucleoprotein complex, subunit Gar1/Naf1
InterPro IPR010613 Pescadillo
InterPro IPR012948 AARP2CN
InterPro IPR016443 RNA 3'-terminal phosphate cyclase type 2
InterPro IPR018978 Ribosome maturation protein SDO1/SBDS, central domain
InterPro IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type
InterPro IPR027193 Nucleolar complex protein 4

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0000005 obsolete ribosomal chaperone activity consider GO:0042254

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0042254 based on ALL annotations
The top 100 of 2,871 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ribosome biogenesis
290.51 100.00 671,012 671,012
rRNA processing
80.10 20.72 305,159 1,106,747
ribosomal small subunit biogenesis
166.84 19.00 148,391 258,396
nucleolus
55.75 12.27 170,311 887,530
ribosomal small subunit binding
175.36 10.08 72,418 119,972
ribosome binding
62.21 9.98 105,748 493,807
ribosomal small subunit assembly
113.64 8.72 67,668 172,986
GTPase activity
30.28 7.83 160,380 1,538,801
small-subunit processome
104.31 7.51 58,227 162,176
ribosomal large subunit assembly
104.35 7.42 57,400 159,797
Totals 4591446 138998419
No co-occurrence statistics for GO:0042254 based on MANUAL annotations
The top 100 of 492 co-occurring terms
Co-occurring Term PR S% #Together #Compared
ribosome biogenesis
1,237.36 100.00 1,044 1,044
preribosome binding
955.58 14.31 156 202
box H/ACA snoRNP assembly
860.41 9.63 105 151
sno(s)RNA-containing ribonucleoprotein complex
461.89 8.88 109 292
ribosomal small subunit binding
134.22 4.44 73 673
cytosolic large ribosomal subunit
24.07 1.79 195 10,026
nucleolus
22.51 1.74 311 17,099
ATP hydrolysis activity
19.41 1.44 159 10,138
ribosomal small subunit biogenesis
21.41 1.08 29 1,676
structural constituent of ribosome
13.51 1.05 224 20,510
Totals 3294 182133

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_generic 141
goslim_candida 86
goslim_pir 439
goslim_pombe 61
goslim_prokaryote 97
goslim_chembl 296
goslim_drosophila 173
goslim_prokaryote_ribbon 49

Change Log

Timestamp Action Category Detail
2024-02-24 Added SUBSET goslim_prokaryote_ribbon
2023-12-15 Added SUBSET goslim_prokaryote
2022-04-08 Deleted SUBSET goslim_aspergillus
2019-11-09 Added SUBSET goslim_drosophila
2017-11-01 Deleted SYNONYM ribosomal chaperone activity
2017-11-01 Deleted XREF Wikipedia:Ribosome_biogenesis
2015-05-19 Deleted SUBSET goslim_ChEMBL
2015-05-19 Added SUBSET goslim_chembl
2015-05-11 Added SUBSET goslim_ChEMBL
2013-04-18 Updated SUBSET goslim_candida
Timestamp Action Category Detail
2008-07-25 Updated TERM ribosome biogenesis
2002-04-23 Added TERM ribosome biogenesis and assembly
Timestamp Action Category Detail
2017-11-01 Deleted SYNONYM ribosomal chaperone activity
2010-12-03 Deleted DEFINITION The process of the formation of the constituents of the ribosome subunits, their assembly, and their transport to the sites of protein synthesis.
2010-12-03 Added DEFINITION A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
2008-07-25 Deleted SYNONYM ribosome biogenesis
2008-07-25 Added SYNONYM ribosome biogenesis and assembly
2008-05-13 Added DEFINITION The process of the formation of the constituents of the ribosome subunits, their assembly, and their transport to the sites of protein synthesis.
2008-05-12 Deleted DEFINITION The process of the formation of the constituents of the ribosome subunits, their assembly, and their transport to the sites of protein synthesis.
2007-08-09 Added SYNONYM ribosome biogenesis
2007-08-09 Deleted SYNONYM ribosome biogenesis
2007-08-09 Deleted SYNONYM ribosomal chaperone activity
2007-08-09 Added SYNONYM ribosomal chaperone activity
2007-01-15 Added SYNONYM ribosome biogenesis
2007-01-09 Updated DEFINITION The process of the formation of the constituents of the ribosome subunits, their assembly, and their transport to the sites of protein synthesis.
2005-08-10 Added SYNONYM ribosomal chaperone activity
2002-11-27 Added DEFINITION The processes of biogenesis and assembly of the ribosome and its subunits.
Timestamp Action Category Detail
2009-03-20 Deleted RELATION is a GO:0006996 (organelle organization)
2008-04-01 Updated RELATION is a GO:0006996 (organelle organization)
2008-04-01 Updated RELATION is a GO:0022613 (ribonucleoprotein complex biogenesis)
Timestamp Action Category Detail
2017-11-01 Deleted XREF Wikipedia:Ribosome_biogenesis
2009-03-29 Added XREF Wikipedia:Ribosome_biogenesis
Timestamp Action Category Detail
2024-02-24 Added SUBSET goslim_prokaryote_ribbon
2023-12-15 Added SUBSET goslim_prokaryote
2022-04-08 Deleted SUBSET goslim_aspergillus
2019-11-09 Added SUBSET goslim_drosophila
2015-05-19 Deleted SUBSET goslim_ChEMBL
2015-05-19 Added SUBSET goslim_chembl
2015-05-11 Added SUBSET goslim_ChEMBL
2013-04-18 Updated SUBSET goslim_candida
2013-04-18 Updated SUBSET goslim_pombe
2013-04-18 Updated SUBSET goslim_aspergillus
2013-04-18 Updated SUBSET goslim_generic
2013-04-18 Updated SUBSET goslim_pir
2011-11-05 Added SUBSET goslim_aspergillus
2011-08-14 Deleted SUBSET goslim_yeast
2010-12-05 Added SUBSET goslim_generic
2009-05-11 Added SUBSET goslim_pombe
2008-06-09 Added SUBSET goslim_yeast
2008-06-09 Added SUBSET goslim_pir
2008-06-09 Added SUBSET goslim_candida
2007-01-15 Added SECONDARY GO:0007046 (ribosome biogenesis)
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