GO:0042254
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ribosome biogenesis
Biological Process
Definition (GO:0042254 GONUTS page)
A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis. PMID:26404467
Secondary IDs
GO:0007046
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
ribosome biogenesis and assembly | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0042254
Child Term | Relationship to GO:0042254 |
---|---|
regulation of ribosome biogenesis
|
regulates |
ribosomal subunit export from nucleus
|
part_of |
ribosomal large subunit biogenesis
|
part_of |
positive regulation of ribosome biogenesis
|
positively_regulates |
rRNA processing
|
part_of |
negative regulation of ribosome biogenesis
|
negatively_regulates |
ribosome assembly
|
part_of |
ribosomal small subunit biogenesis
|
part_of |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | Q6MG08 | 10116 | ABCF1_RAT | GO:0042254 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q6P542 | 10090 | ABCF1_MOUSE | GO:0042254 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q767L0 | 9823 | ABCF1_PIG | GO:0042254 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q7YR37 | 9598 | ABCF1_PANTR | GO:0042254 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | Q8NE71-2 | 9606 | ABCF1_HUMAN | GO:0042254 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:19570978 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR004037 | Large ribosomal subunit protein eL8-like, conserved site |
InterPro | IPR007023 | Ribosomal biogenesis regulatory protein |
InterPro | IPR007264 | H/ACA ribonucleoprotein complex, subunit Nop10 |
InterPro | IPR007504 | H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 |
InterPro | IPR010613 | Pescadillo |
InterPro | IPR012948 | AARP2CN |
InterPro | IPR016443 | RNA 3'-terminal phosphate cyclase type 2 |
InterPro | IPR018978 | Ribosome maturation protein SDO1/SBDS, central domain |
InterPro | IPR023532 | H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type |
InterPro | IPR027193 | Nucleolar complex protein 4 |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0000005 | obsolete ribosomal chaperone activity | consider GO:0042254 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0042254 based on ALL annotations
The top 100 of 2,871 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ribosome biogenesis
|
290.51 | 100.00 | 671,012 | 671,012 |
rRNA processing
|
80.10 | 20.72 | 305,159 | 1,106,747 |
ribosomal small subunit biogenesis
|
166.84 | 19.00 | 148,391 | 258,396 |
nucleolus
|
55.75 | 12.27 | 170,311 | 887,530 |
ribosomal small subunit binding
|
175.36 | 10.08 | 72,418 | 119,972 |
ribosome binding
|
62.21 | 9.98 | 105,748 | 493,807 |
ribosomal small subunit assembly
|
113.64 | 8.72 | 67,668 | 172,986 |
GTPase activity
|
30.28 | 7.83 | 160,380 | 1,538,801 |
small-subunit processome
|
104.31 | 7.51 | 58,227 | 162,176 |
ribosomal large subunit assembly
|
104.35 | 7.42 | 57,400 | 159,797 |
Totals | 4591446 | 138998419 |
No co-occurrence statistics for GO:0042254 based on MANUAL annotations
The top 100 of 492 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
ribosome biogenesis
|
1,237.36 | 100.00 | 1,044 | 1,044 |
preribosome binding
|
955.58 | 14.31 | 156 | 202 |
box H/ACA snoRNP assembly
|
860.41 | 9.63 | 105 | 151 |
sno(s)RNA-containing ribonucleoprotein complex
|
461.89 | 8.88 | 109 | 292 |
ribosomal small subunit binding
|
134.22 | 4.44 | 73 | 673 |
cytosolic large ribosomal subunit
|
24.07 | 1.79 | 195 | 10,026 |
nucleolus
|
22.51 | 1.74 | 311 | 17,099 |
ATP hydrolysis activity
|
19.41 | 1.44 | 159 | 10,138 |
ribosomal small subunit biogenesis
|
21.41 | 1.08 | 29 | 1,676 |
structural constituent of ribosome
|
13.51 | 1.05 | 224 | 20,510 |
Totals | 3294 | 182133 |
GO Slims
This term is present in the following GO Consortium-maintained GO slims:
GO slim name | Total Number of Terms in Slim |
---|---|
goslim_generic | 141 |
goslim_candida | 86 |
goslim_pir | 439 |
goslim_pombe | 61 |
goslim_prokaryote | 97 |
goslim_chembl | 296 |
goslim_drosophila | 173 |
goslim_prokaryote_ribbon | 49 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-02-24 | Added | SUBSET | goslim_prokaryote_ribbon |
2023-12-15 | Added | SUBSET | goslim_prokaryote |
2022-04-08 | Deleted | SUBSET | goslim_aspergillus |
2019-11-09 | Added | SUBSET | goslim_drosophila |
2017-11-01 | Deleted | SYNONYM | ribosomal chaperone activity |
2017-11-01 | Deleted | XREF | Wikipedia:Ribosome_biogenesis |
2015-05-19 | Deleted | SUBSET | goslim_ChEMBL |
2015-05-19 | Added | SUBSET | goslim_chembl |
2015-05-11 | Added | SUBSET | goslim_ChEMBL |
2013-04-18 | Updated | SUBSET | goslim_candida |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-07-25 | Updated | TERM | ribosome biogenesis |
2002-04-23 | Added | TERM | ribosome biogenesis and assembly |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-11-01 | Deleted | SYNONYM | ribosomal chaperone activity |
2010-12-03 | Deleted | DEFINITION | The process of the formation of the constituents of the ribosome subunits, their assembly, and their transport to the sites of protein synthesis. |
2010-12-03 | Added | DEFINITION | A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis. |
2008-07-25 | Deleted | SYNONYM | ribosome biogenesis |
2008-07-25 | Added | SYNONYM | ribosome biogenesis and assembly |
2008-05-13 | Added | DEFINITION | The process of the formation of the constituents of the ribosome subunits, their assembly, and their transport to the sites of protein synthesis. |
2008-05-12 | Deleted | DEFINITION | The process of the formation of the constituents of the ribosome subunits, their assembly, and their transport to the sites of protein synthesis. |
2007-08-09 | Added | SYNONYM | ribosome biogenesis |
2007-08-09 | Deleted | SYNONYM | ribosome biogenesis |
2007-08-09 | Deleted | SYNONYM | ribosomal chaperone activity |
2007-08-09 | Added | SYNONYM | ribosomal chaperone activity |
2007-01-15 | Added | SYNONYM | ribosome biogenesis |
2007-01-09 | Updated | DEFINITION | The process of the formation of the constituents of the ribosome subunits, their assembly, and their transport to the sites of protein synthesis. |
2005-08-10 | Added | SYNONYM | ribosomal chaperone activity |
2002-11-27 | Added | DEFINITION | The processes of biogenesis and assembly of the ribosome and its subunits. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-03-20 | Deleted | RELATION | is a GO:0006996 (organelle organization) |
2008-04-01 | Updated | RELATION | is a GO:0006996 (organelle organization) |
2008-04-01 | Updated | RELATION | is a GO:0022613 (ribonucleoprotein complex biogenesis) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-11-01 | Deleted | XREF | Wikipedia:Ribosome_biogenesis |
2009-03-29 | Added | XREF | Wikipedia:Ribosome_biogenesis |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-02-24 | Added | SUBSET | goslim_prokaryote_ribbon |
2023-12-15 | Added | SUBSET | goslim_prokaryote |
2022-04-08 | Deleted | SUBSET | goslim_aspergillus |
2019-11-09 | Added | SUBSET | goslim_drosophila |
2015-05-19 | Deleted | SUBSET | goslim_ChEMBL |
2015-05-19 | Added | SUBSET | goslim_chembl |
2015-05-11 | Added | SUBSET | goslim_ChEMBL |
2013-04-18 | Updated | SUBSET | goslim_candida |
2013-04-18 | Updated | SUBSET | goslim_pombe |
2013-04-18 | Updated | SUBSET | goslim_aspergillus |
2013-04-18 | Updated | SUBSET | goslim_generic |
2013-04-18 | Updated | SUBSET | goslim_pir |
2011-11-05 | Added | SUBSET | goslim_aspergillus |
2011-08-14 | Deleted | SUBSET | goslim_yeast |
2010-12-05 | Added | SUBSET | goslim_generic |
2009-05-11 | Added | SUBSET | goslim_pombe |
2008-06-09 | Added | SUBSET | goslim_yeast |
2008-06-09 | Added | SUBSET | goslim_pir |
2008-06-09 | Added | SUBSET | goslim_candida |
2007-01-15 | Added | SECONDARY | GO:0007046 (ribosome biogenesis) |
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