This term is obsolete.

GO:0042582 JSON

azurophil granule

Cellular Component

Definition (GO:0042582 GONUTS page)

Primary lysosomal granule readily stainable with a Romanowsky stain. PMID:17152095 PMID:28717070 PMID:5914694

1,170 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
primary granule exact

Ancestor Chart

Ancestor chart for GO:0042582
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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0042582

Child Term Relationship to
GO:0042582
GO:0035577
azurophil granule membrane
part_of
GO:0035578
azurophil granule lumen
part_of

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0042582 azurophil granule Never in Taxon 4751 Fungi
GO:0042582 azurophil granule Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0D1E8X3 5270 A0A0D1E8X3_MYCMD GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A0G2JZ79 10116 SIR1_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2K320 10116 A0A0G2K320_RAT GO:0005764 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1D8PHF8 237561 A0A1D8PHF8_CANAL GO:0031410 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:8760936
NOT-qualified manual protein A0A1L8G9S0 8355 A0A1L8G9S0_XENLA GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1S4L3K3 6945 A0A1S4L3K3_IXOSC GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1W2Q633 10116 A0A1W2Q633_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A2K5ATM2 6239 A0A2K5ATM2_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0042582 based on ALL annotations
The top 100 of 359 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0042582
azurophil granule
255,354.20 100.00 776 776
GO:1905379
beta-N-acetylhexosaminidase complex
255,354.22 24.10 187 187
GO:0042581
specific granule
80,125.11 22.27 337 1,074
GO:0030209
dermatan sulfate proteoglycan catabolic process
137,379.02 19.07 177 329
GO:0070820
tertiary granule
126,217.94 18.15 173 350
GO:0051651
maintenance of location in cell
87,793.69 15.77 175 509
GO:0090174
organelle membrane fusion
252,452.44 11.20 87 88
GO:1902685
positive regulation of receptor localization to synapse
119,580.50 10.85 96 205
GO:0030348
syntaxin-3 binding
216,068.95 9.75 77 91
GO:0002553
histamine secretion by mast cell
84,139.70 9.04 86 261
Totals 10814 1178169
No co-occurrence statistics for GO:0042582 based on MANUAL annotations
The top 100 of 332 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0042582
azurophil granule
40,329.52 100.00 35 35
GO:0042581
specific granule
12,935.88 23.94 17 53
GO:0070820
tertiary granule
16,606.27 15.56 7 17
GO:0002149
hypochlorous acid biosynthetic process
40,329.52 11.43 4 4
GO:1905379
beta-N-acetylhexosaminidase complex
26,886.34 10.81 4 6
GO:0030348
syntaxin-3 binding
8,401.98 9.26 5 24
GO:0002679
respiratory burst involved in defense response
11,522.72 8.89 4 14
GO:0032724
positive regulation of fractalkine production
24,197.71 8.11 3 5
GO:1990268
response to gold nanoparticle
24,197.71 8.11 3 5
GO:0043312
neutrophil degranulation
4,801.13 6.94 5 42
Totals 263 7685

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2024-03-22 Deleted CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2024-03-21 Added DEFINITION Primary lysosomal granule readily stainable with a Romanowsky stain.
2024-03-21 Deleted DEFINITION Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2008-05-13 Added DEFINITION Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
2008-05-12 Deleted DEFINITION Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
2008-04-01 Updated RELATION is a GO:0030141 (secretory granule)
2008-04-01 Updated RELATION is a GO:0005766 (primary lysosome)
Timestamp Action Category Detail
2003-02-12 Added TERM azurophil granule
Timestamp Action Category Detail
2024-03-21 Added DEFINITION Primary lysosomal granule readily stainable with a Romanowsky stain.
2024-03-21 Deleted DEFINITION Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
2008-05-13 Added DEFINITION Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
2008-05-12 Deleted DEFINITION Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
2007-08-09 Added SYNONYM primary granule
2007-08-09 Deleted SYNONYM primary granule
2004-04-19 Added SYNONYM primary granule
2004-04-16 Deleted SYNONYM primary granule
2003-03-26 Added DEFINITION Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
2003-02-12 Added SYNONYM primary granule
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0030141 (secretory granule)
2008-04-01 Updated RELATION is a GO:0005766 (primary lysosome)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2024-03-22 Deleted CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:7742 (Vertebrata)
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