This term is obsolete.

GO:0042627 JSON

chylomicron

Cellular Component

Definition (GO:0042627 GONUTS page)

A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues. PMID:10580165

13,156 annotations

Ancestor Chart

Ancestor chart for GO:0042627
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0042627

Child Term Relationship to
GO:0042627
mature chylomicron
is_a
chylomicron remnant
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0042627 chylomicron Never in Taxon 4890 Ascomycota

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q99470 9606 SDF2_HUMAN GO:0005576 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A0A0G2JY81 10116 A0A0G2JY81_RAT GO:0005615 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A7U3L4H9 10116 A0A7U3L4H9_RAT GO:0005576 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6AAN5 10116 A0A8I6AAN5_RAT GO:0005615 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A1Z7L0 7227 A1Z7L0_DROME GO:0005615 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:35714143
NOT-qualified manual protein A4QNU9 7955 A4QNU9_DANRE GO:0005615 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:22292055
NOT-qualified manual protein A6HTD8 10116 A6HTD8_RAT GO:0005615 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6HWX9 10116 A6HWX9_RAT GO:0005615 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K8X7 10116 A6K8X7_RAT GO:0005576 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein B1WC21 10116 B1WC21_RAT GO:0005615 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Cross-references

Database ID Description
InterPro IPR008019 Apolipoprotein C-II
InterPro IPR008404 Apovitellenin I
UniProtKB-KW KW-0162 Chylomicron
Wikipedia Chylomicron

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0042627 based on ALL annotations
The top 100 of 444 co-occurring terms
Co-occurring Term PR S% #Together #Compared
chylomicron
21,120.75 100.00 9,382 9,382
very-low-density lipoprotein particle
17,371.72 82.09 9,360 11,380
low-density lipoprotein particle
17,221.98 59.80 6,489 7,958
phosphatidylcholine-sterol O-acyltransferase activator activity
21,091.98 39.05 3,666 3,671
acylglycerol homeostasis
20,480.03 37.71 3,580 3,692
phospholipid efflux
17,177.97 36.82 3,773 4,639
extracellular vesicle
16,218.45 34.15 3,573 4,653
high-density lipoprotein particle
9,929.10 29.90 4,231 9,000
cholesterol transfer activity
7,256.60 29.70 6,440 18,744
mature chylomicron
16,328.60 27.23 2,777 3,592
Totals 126710 1602046
No co-occurrence statistics for GO:0042627 based on MANUAL annotations
The top 100 of 353 co-occurring terms
Co-occurring Term PR S% #Together #Compared
chylomicron
12,064.39 100.00 117 117
phosphatidylcholine-sterol O-acyltransferase activator activity
11,928.83 74.58 88 89
acylglycerol homeostasis
10,794.45 66.93 85 95
very-low-density lipoprotein particle
6,689.73 55.45 117 211
phospholipid efflux
6,686.29 48.17 92 166
low-density lipoprotein particle
6,369.40 44.04 85 161
high-density lipoprotein particle
5,718.02 41.74 91 192
cholesterol transfer activity
3,664.61 27.73 89 293
intermediate-density lipoprotein particle
6,294.46 24.00 36 69
cholesterol efflux
3,048.88 23.72 93 368
Totals 1799 10970

Change Log

Timestamp Action Category Detail
2025-02-06 Added CONSTRAINT never_in_taxon NCBITaxon:4890 (Ascomycota)
2009-02-25 Added XREF Wikipedia:Chylomicron
2008-05-13 Added DEFINITION A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues.
2008-05-12 Deleted DEFINITION A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues.
2008-04-27 Updated DEFINITION A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues.
2008-04-17 Deleted RELATION part of GO:0005615 (extracellular space)
2008-04-10 Deleted RELATION is a GO:0044421 (obsolete extracellular region part)
2008-04-10 Added RELATION is a GO:0034358 (plasma lipoprotein particle)
2008-04-01 Updated RELATION is a GO:0044421 (obsolete extracellular region part)
2008-04-01 Updated RELATION part of GO:0005615 (extracellular space)
Timestamp Action Category Detail
2003-04-04 Added TERM chylomicron
Timestamp Action Category Detail
2008-05-13 Added DEFINITION A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues.
2008-05-12 Deleted DEFINITION A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues.
2008-04-27 Updated DEFINITION A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues.
2003-04-04 Added DEFINITION A particle composed of a central core of triglycerides surrounded by a protein-phospholipid coating. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues.
Timestamp Action Category Detail
2008-04-17 Deleted RELATION part of GO:0005615 (extracellular space)
2008-04-10 Deleted RELATION is a GO:0044421 (obsolete extracellular region part)
2008-04-10 Added RELATION is a GO:0034358 (plasma lipoprotein particle)
2008-04-01 Updated RELATION is a GO:0044421 (obsolete extracellular region part)
2008-04-01 Updated RELATION part of GO:0005615 (extracellular space)
Timestamp Action Category Detail
2009-02-25 Added XREF Wikipedia:Chylomicron
Timestamp Action Category Detail
2025-02-06 Added CONSTRAINT never_in_taxon NCBITaxon:4890 (Ascomycota)
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