GO:0042754
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negative regulation of circadian rhythm
Biological Process
Definition (GO:0042754 GONUTS page)
Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| downregulation of circadian rhythm | exact |
| down-regulation of circadian rhythm | exact |
| down regulation of circadian rhythm | exact |
| inhibition of circadian rhythm | narrow |
Ancestor Chart
Ancestor chart for GO:0042754
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0042754
| Child Term | Relationship to GO:0042754 |
|---|---|
|
Cry-Per complex
|
capable_of_part_of |
|
negative regulation of circadian sleep/wake cycle, wakefulness
|
is_a |
|
negative regulation of circadian sleep/wake cycle, sleep
|
is_a |
|
negative regulation of locomotor rhythm
|
is_a |
Cross-references
| Database | ID | Description |
|---|---|---|
| InterPro | IPR031602 | Clock-interacting pacemaker |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0042754 based on ALL annotations
The top 100 of 248 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
negative regulation of circadian rhythm
|
103,691.71 | 100.00 | 1,911 | 1,911 |
|
negative regulation of glucocorticoid secretion
|
103,691.71 | 9.26 | 177 | 177 |
|
negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
|
42,183.68 | 8.24 | 179 | 440 |
|
Cry-Per complex
|
103,691.72 | 6.49 | 124 | 124 |
|
response to activity
|
11,636.88 | 5.38 | 179 | 1,595 |
|
regulation of sodium-dependent phosphate transport
|
100,671.56 | 5.22 | 100 | 103 |
|
perinucleolar chromocenter
|
57,678.52 | 4.49 | 89 | 160 |
|
transposable element silencing by mRNA destabilization
|
31,604.67 | 4.21 | 89 | 292 |
|
secondary piRNA processing
|
31,283.26 | 4.20 | 89 | 295 |
|
piRNA-mediated gene silencing by mRNA destabilization
|
25,850.32 | 4.08 | 89 | 357 |
| Totals | 12585 | 3112238 | ||
No co-occurrence statistics for GO:0042754 based on MANUAL annotations
The top 100 of 169 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
negative regulation of circadian rhythm
|
27,144.86 | 100.00 | 52 | 52 |
|
Cry-Per complex
|
27,144.87 | 15.38 | 8 | 8 |
|
negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway
|
7,005.13 | 10.67 | 8 | 31 |
|
dendritic transport of messenger ribonucleoprotein complex
|
9,694.60 | 8.20 | 5 | 14 |
|
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
|
9,048.29 | 8.06 | 5 | 15 |
|
negative regulation of glucocorticoid secretion
|
27,144.87 | 7.69 | 4 | 4 |
|
positive regulation of sister chromatid cohesion
|
7,540.24 | 7.69 | 5 | 18 |
|
regulation of glutamate uptake involved in transmission of nerve impulse
|
15,511.35 | 7.27 | 4 | 7 |
|
DNA (6-4) photolyase activity
|
13,572.43 | 7.14 | 4 | 8 |
|
lactate biosynthetic process
|
9,870.86 | 6.78 | 4 | 11 |
| Totals | 536 | 31714 | ||
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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- Cross-references
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2010-10-03 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of a circadian rhythm behavior. |
| 2010-10-03 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior. |
| 2008-05-13 | Added | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of a circadian rhythm behavior. |
| 2008-05-12 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of a circadian rhythm behavior. |
| 2008-04-01 | Updated | RELATION | is a GO:0048519 (negative regulation of biological process) |
| 2008-04-01 | Updated | RELATION | is a GO:0042752 (regulation of circadian rhythm) |
| 2008-04-01 | Added | RELATION | negatively regulates GO:0007623 (circadian rhythm) |
| 2007-08-09 | Deleted | SYNONYM | inhibition of circadian rhythm |
| 2007-08-09 | Deleted | SYNONYM | down regulation of circadian rhythm |
| 2007-08-09 | Added | SYNONYM | down regulation of circadian rhythm |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2003-06-11 | Added | TERM | negative regulation of circadian rhythm |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2010-10-03 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of a circadian rhythm behavior. |
| 2010-10-03 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior. |
| 2008-05-13 | Added | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of a circadian rhythm behavior. |
| 2008-05-12 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of a circadian rhythm behavior. |
| 2007-08-09 | Deleted | SYNONYM | inhibition of circadian rhythm |
| 2007-08-09 | Deleted | SYNONYM | down regulation of circadian rhythm |
| 2007-08-09 | Added | SYNONYM | down regulation of circadian rhythm |
| 2007-08-09 | Added | SYNONYM | down-regulation of circadian rhythm |
| 2007-08-09 | Added | SYNONYM | downregulation of circadian rhythm |
| 2007-08-09 | Added | SYNONYM | inhibition of circadian rhythm |
| 2007-08-09 | Deleted | SYNONYM | down-regulation of circadian rhythm |
| 2007-08-09 | Deleted | SYNONYM | downregulation of circadian rhythm |
| 2007-02-23 | Added | SYNONYM | downregulation of circadian rhythm |
| 2007-02-23 | Added | SYNONYM | inhibition of circadian rhythm |
| 2007-02-23 | Added | SYNONYM | down regulation of circadian rhythm |
| 2007-02-23 | Added | SYNONYM | down-regulation of circadian rhythm |
| 2006-05-04 | Updated | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of a circadian rhythm behavior. |
| 2005-10-21 | Updated | DEFINITION | Any process that stops, prevents or reduces the rate, frequency or extent of a circadian rhythm behavior. |
| 2003-07-08 | Updated | DEFINITION | Any process that stops, prevents or reduces the rate of a circadian rhythm behavior. |
| 2003-06-11 | Added | DEFINITION | Any process that stops, prevents or reduces the rate of a circadian rhythm behaviour. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-04-01 | Updated | RELATION | is a GO:0048519 (negative regulation of biological process) |
| 2008-04-01 | Updated | RELATION | is a GO:0042752 (regulation of circadian rhythm) |
| 2008-04-01 | Added | RELATION | negatively regulates GO:0007623 (circadian rhythm) |
| Timestamp | Action | Category | Detail |
|---|
| Timestamp | Action | Category | Detail |
|---|
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