This term is obsolete.

GO:0042784 JSON

symbiont-mediated suppression of host complement activation

Biological Process

Definition (GO:0042784 GONUTS page)

A process by which a symbiont inhibits or disrupts the normal execution of the activation of complement in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction. PMID:20194595 PMID:21191012 PMID:25830295 PMID:7745740

Secondary IDs

GO:0051811

556 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
suppression of complement activation by another organism broad
active immune evasion via modulation of host complement system exact
active evasion of host immune response via regulation of host complement system related
active evasion of immune response of other organism via regulation of complement system of other organism involved in symbiotic interaction broad
active immune evasion via regulation of host complement system exact
evasion of host immune response via regulation of host complement system exact
evasion of host immune response via modulation of host complement system exact

Ancestor Chart

Ancestor chart for GO:0042784
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0042784

Child Term Relationship to
GO:0042784
symbiont-mediated suppression of host complement activation by recruitment of complement control protein
is_a
symbiont-mediated suppression of host complement activation by inactivation of complement proteins
is_a
symbiont-mediated suppression of host complement activation by complement sequestering
is_a
symbiont-mediated suppression of host complement activation by activation of host proteases
is_a

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0042784 symbiont-mediated suppression of host complement activation Never in Taxon 33090 Viridiplantae
GO:0042784 symbiont-mediated suppression of host complement activation Never in Taxon 33208 Metazoa
GO:0042784 symbiont-mediated suppression of host complement activation Never in Taxon 4895 Schizosaccharomyces

More information on taxon constraints in GO is available here

Cross-references

Database ID Description
UniProtKB-KW KW-1087 Inhibition of host complement factors by virus
VZ 811

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0039573 obsolete suppression by virus of host complement activation consider GO:0042784
GO:0044629 obsolete negative regulation of complement activation, classical pathway in another organism consider GO:0042784
GO:0044632 obsolete negative regulation of complement activation, lectin pathway in another organism consider GO:0042784
GO:0044634 obsolete negative regulation of complement activation, alternative pathway in another organism consider GO:0042784
GO:0044637 obsolete envenomation resulting in negative regulation of complement activation, classical pathway in another organism consider GO:0042784
GO:0044640 obsolete envenomation resulting in negative regulation of complement activation, lectin pathway in another organism consider GO:0042784
GO:0044644 obsolete envenomation resulting in negative regulation of complement activation, alternative pathway in another organism consider GO:0042784
GO:0044645 obsolete modulation of complement activation in another organism consider GO:0042784
GO:0141114 obsolete symbiont-mediated suppression of host complement activation replaced_by GO:0042784

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0042784 based on ALL annotations
The top 97 of 97 co-occurring terms
Co-occurring Term PR S% #Together #Compared
symbiont-mediated suppression of host complement activation
351,875.06 100.00 554 554
adhesion receptor-mediated virion attachment to host cell
68,374.43 19.33 540 2,779
negative regulation of complement activation
2,559.09 0.24 2 275
complement binding
1,104.79 0.22 4 1,274
glideosome
87,968.77 0.18 1 4
inner membrane pellicle complex
17,593.75 0.17 1 20
paraflagellar rod
7,330.73 0.17 1 48
elastin catabolic process
2,330.30 0.14 1 151
host cell surface binding
933.36 0.11 1 377
virus-mediated perturbation of host defense response
306.39 0.09 318 365,209
Totals 3302 249744945
No co-occurrence statistics for GO:0042784 based on MANUAL annotations
The top 33 of 33 co-occurring terms
Co-occurring Term PR S% #Together #Compared
symbiont-mediated suppression of host complement activation
184,542.70 100.00 7 7
glideosome
46,135.68 10.00 1 4
elastin catabolic process
13,181.62 5.00 1 14
inner membrane pellicle complex
9,227.14 3.85 1 20
host cell surface binding
6,363.54 2.86 1 29
uropod
4,731.86 2.22 1 39
paraflagellar rod
3,844.64 1.85 1 48
fibrinogen binding
3,766.18 1.82 1 49
complement component C1q complex binding
2,460.57 1.23 1 75
IgE binding
2,050.47 1.04 1 90
Totals 44 537195

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:33090 (Viridiplantae)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:33208 (Metazoa)
2023-12-26 Added XREF VZ:811
2023-12-26 Added DEFINITION A process by which a symbiont inhibits or disrupts the normal execution of the activation of complement in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2023-12-26 Added SYNONYM suppression of complement activation by another organism
2023-12-26 Added RELATION is a GO:0052170 (symbiont-mediated suppression of host innate immune response)
2023-12-26 Deleted RELATION is a GO:0042783 (evasion of host immune response)
2023-12-26 Deleted DEFINITION Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2023-12-26 Added SYNONYM evasion of host immune response via modulation of host complement system
Timestamp Action Category Detail
2023-12-26 Updated TERM symbiont-mediated suppression of host complement activation
2022-07-15 Updated TERM evasion of host immune response via modulation of host complement system
2019-09-29 Updated TERM evasion of host immune response via regulation of host complement system
2007-01-25 Updated TERM active evasion of host immune response via regulation of host complement system
2005-12-10 Updated TERM active evasion of host immune response via regulation of complement system
2005-03-01 Updated TERM active immune evasion via regulation of complement system
2003-07-10 Added TERM active immune evasion via modulation of complement system
Timestamp Action Category Detail
2023-12-26 Added DEFINITION A process by which a symbiont inhibits or disrupts the normal execution of the activation of complement in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2023-12-26 Added SYNONYM suppression of complement activation by another organism
2023-12-26 Deleted DEFINITION Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2023-12-26 Added SYNONYM evasion of host immune response via modulation of host complement system
2022-07-15 Added SYNONYM evasion of host immune response via regulation of host complement system
2019-09-29 Added SYNONYM active evasion of host immune response via regulation of host complement system
2019-09-12 Added SYNONYM active evasion of immune response of other organism via regulation of complement system of other organism involved in symbiotic interaction
2008-05-13 Added DEFINITION Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2008-05-12 Deleted DEFINITION Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2007-08-09 Deleted SYNONYM active immune evasion via regulation of host complement system
2007-08-09 Deleted SYNONYM active immune evasion via modulation of host complement system
2007-08-09 Added SYNONYM active immune evasion via modulation of host complement system
2007-08-09 Added SYNONYM active immune evasion via regulation of host complement system
2007-01-25 Added SYNONYM active immune evasion via modulation of host complement system
2007-01-25 Deleted SYNONYM active immune evasion via modulation of complement system
2007-01-25 Added SYNONYM active immune evasion via regulation of host complement system
2007-01-25 Deleted SYNONYM active immune evasion via regulation of complement system
2005-12-10 Added SYNONYM active immune evasion via regulation of complement system
2005-12-08 Updated DEFINITION Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction.
2005-03-01 Added SYNONYM active immune evasion via modulation of complement system
2003-07-22 Updated DEFINITION Any mechanism of active immune avoidance which works by regulating the host complement system e. g by possessing complement receptors which mediate attachment to, then infection of host macrophages, which are eventually destroyed.
2003-07-10 Added DEFINITION Any mechanism of active immune avoidance which works by regulating the host complement system e.g by possessing complement receptors which mediate attachment to, then infection of host macrophages, which are eventually destroyed.
Timestamp Action Category Detail
2023-12-26 Added RELATION is a GO:0052170 (symbiont-mediated suppression of host innate immune response)
2023-12-26 Deleted RELATION is a GO:0042783 (evasion of host immune response)
2019-09-12 Deleted RELATION is a GO:0051811 (active evasion of immune response of other organism via regulation of complement system of other organism involved in symbiotic interaction)
2008-04-01 Updated RELATION is a GO:0051811 (active evasion of immune response of other organism via regulation of complement system of other organism involved in symbiotic interaction)
2008-04-01 Updated RELATION is a GO:0042783 (evasion of host immune response)
Timestamp Action Category Detail
2023-12-26 Added XREF VZ:811
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:33090 (Viridiplantae)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4895 (Schizosaccharomyces)
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:33208 (Metazoa)
2019-09-12 Added SECONDARY GO:0051811 (active evasion of immune response of other organism via regulation of complement system of other organism involved in symbiotic interaction)
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