GO:0042784
JSON
symbiont-mediated suppression of host complement activation
Biological Process
Definition (GO:0042784 GONUTS page)
A process by which a symbiont inhibits or disrupts the normal execution of the activation of complement in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction. PMID:20194595 PMID:21191012 PMID:25830295 PMID:7745740
Secondary IDs
GO:0051811
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
suppression of complement activation by another organism | broad |
active immune evasion via modulation of host complement system | exact |
active evasion of host immune response via regulation of host complement system | related |
active evasion of immune response of other organism via regulation of complement system of other organism involved in symbiotic interaction | broad |
active immune evasion via regulation of host complement system | exact |
evasion of host immune response via regulation of host complement system | exact |
evasion of host immune response via modulation of host complement system | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0042784
Child Term | Relationship to GO:0042784 |
---|---|
symbiont-mediated suppression of host complement activation by recruitment of complement control protein
|
is_a |
symbiont-mediated suppression of host complement activation by inactivation of complement proteins
|
is_a |
symbiont-mediated suppression of host complement activation by complement sequestering
|
is_a |
symbiont-mediated suppression of host complement activation by activation of host proteases
|
is_a |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0042784 | symbiont-mediated suppression of host complement activation | Never in Taxon | 33090 | Viridiplantae | |
GO:0042784 | symbiont-mediated suppression of host complement activation | Never in Taxon | 33208 | Metazoa | |
GO:0042784 | symbiont-mediated suppression of host complement activation | Never in Taxon | 4895 | Schizosaccharomyces |
More information on taxon constraints in GO is available here
Cross-references
Database | ID | Description |
---|---|---|
UniProtKB-KW | KW-1087 | Inhibition of host complement factors by virus |
VZ | 811 |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0039573 | obsolete suppression by virus of host complement activation | consider GO:0042784 |
GO:0044629 | obsolete negative regulation of complement activation, classical pathway in another organism | consider GO:0042784 |
GO:0044632 | obsolete negative regulation of complement activation, lectin pathway in another organism | consider GO:0042784 |
GO:0044634 | obsolete negative regulation of complement activation, alternative pathway in another organism | consider GO:0042784 |
GO:0044637 | obsolete envenomation resulting in negative regulation of complement activation, classical pathway in another organism | consider GO:0042784 |
GO:0044640 | obsolete envenomation resulting in negative regulation of complement activation, lectin pathway in another organism | consider GO:0042784 |
GO:0044644 | obsolete envenomation resulting in negative regulation of complement activation, alternative pathway in another organism | consider GO:0042784 |
GO:0044645 | obsolete modulation of complement activation in another organism | consider GO:0042784 |
GO:0141114 | obsolete symbiont-mediated suppression of host complement activation | replaced_by GO:0042784 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0042784 based on ALL annotations
The top 97 of 97 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
symbiont-mediated suppression of host complement activation
|
351,875.06 | 100.00 | 554 | 554 |
adhesion receptor-mediated virion attachment to host cell
|
68,374.43 | 19.33 | 540 | 2,779 |
negative regulation of complement activation
|
2,559.09 | 0.24 | 2 | 275 |
complement binding
|
1,104.79 | 0.22 | 4 | 1,274 |
glideosome
|
87,968.77 | 0.18 | 1 | 4 |
inner membrane pellicle complex
|
17,593.75 | 0.17 | 1 | 20 |
paraflagellar rod
|
7,330.73 | 0.17 | 1 | 48 |
elastin catabolic process
|
2,330.30 | 0.14 | 1 | 151 |
host cell surface binding
|
933.36 | 0.11 | 1 | 377 |
virus-mediated perturbation of host defense response
|
306.39 | 0.09 | 318 | 365,209 |
Totals | 3302 | 249744945 |
No co-occurrence statistics for GO:0042784 based on MANUAL annotations
The top 33 of 33 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
symbiont-mediated suppression of host complement activation
|
184,542.70 | 100.00 | 7 | 7 |
glideosome
|
46,135.68 | 10.00 | 1 | 4 |
elastin catabolic process
|
13,181.62 | 5.00 | 1 | 14 |
inner membrane pellicle complex
|
9,227.14 | 3.85 | 1 | 20 |
host cell surface binding
|
6,363.54 | 2.86 | 1 | 29 |
uropod
|
4,731.86 | 2.22 | 1 | 39 |
paraflagellar rod
|
3,844.64 | 1.85 | 1 | 48 |
fibrinogen binding
|
3,766.18 | 1.82 | 1 | 49 |
complement component C1q complex binding
|
2,460.57 | 1.23 | 1 | 75 |
IgE binding
|
2,050.47 | 1.04 | 1 | 90 |
Totals | 44 | 537195 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:33090 (Viridiplantae) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4895 (Schizosaccharomyces) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:33208 (Metazoa) |
2023-12-26 | Added | XREF | VZ:811 |
2023-12-26 | Added | DEFINITION | A process by which a symbiont inhibits or disrupts the normal execution of the activation of complement in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
2023-12-26 | Added | SYNONYM | suppression of complement activation by another organism |
2023-12-26 | Added | RELATION | is a GO:0052170 (symbiont-mediated suppression of host innate immune response) |
2023-12-26 | Deleted | RELATION | is a GO:0042783 (evasion of host immune response) |
2023-12-26 | Deleted | DEFINITION | Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
2023-12-26 | Added | SYNONYM | evasion of host immune response via modulation of host complement system |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-12-26 | Updated | TERM | symbiont-mediated suppression of host complement activation |
2022-07-15 | Updated | TERM | evasion of host immune response via modulation of host complement system |
2019-09-29 | Updated | TERM | evasion of host immune response via regulation of host complement system |
2007-01-25 | Updated | TERM | active evasion of host immune response via regulation of host complement system |
2005-12-10 | Updated | TERM | active evasion of host immune response via regulation of complement system |
2005-03-01 | Updated | TERM | active immune evasion via regulation of complement system |
2003-07-10 | Added | TERM | active immune evasion via modulation of complement system |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-12-26 | Added | DEFINITION | A process by which a symbiont inhibits or disrupts the normal execution of the activation of complement in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
2023-12-26 | Added | SYNONYM | suppression of complement activation by another organism |
2023-12-26 | Deleted | DEFINITION | Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
2023-12-26 | Added | SYNONYM | evasion of host immune response via modulation of host complement system |
2022-07-15 | Added | SYNONYM | evasion of host immune response via regulation of host complement system |
2019-09-29 | Added | SYNONYM | active evasion of host immune response via regulation of host complement system |
2019-09-12 | Added | SYNONYM | active evasion of immune response of other organism via regulation of complement system of other organism involved in symbiotic interaction |
2008-05-13 | Added | DEFINITION | Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
2008-05-12 | Deleted | DEFINITION | Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
2007-08-09 | Deleted | SYNONYM | active immune evasion via regulation of host complement system |
2007-08-09 | Deleted | SYNONYM | active immune evasion via modulation of host complement system |
2007-08-09 | Added | SYNONYM | active immune evasion via modulation of host complement system |
2007-08-09 | Added | SYNONYM | active immune evasion via regulation of host complement system |
2007-01-25 | Added | SYNONYM | active immune evasion via modulation of host complement system |
2007-01-25 | Deleted | SYNONYM | active immune evasion via modulation of complement system |
2007-01-25 | Added | SYNONYM | active immune evasion via regulation of host complement system |
2007-01-25 | Deleted | SYNONYM | active immune evasion via regulation of complement system |
2005-12-10 | Added | SYNONYM | active immune evasion via regulation of complement system |
2005-12-08 | Updated | DEFINITION | Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction. |
2005-03-01 | Added | SYNONYM | active immune evasion via modulation of complement system |
2003-07-22 | Updated | DEFINITION | Any mechanism of active immune avoidance which works by regulating the host complement system e. g by possessing complement receptors which mediate attachment to, then infection of host macrophages, which are eventually destroyed. |
2003-07-10 | Added | DEFINITION | Any mechanism of active immune avoidance which works by regulating the host complement system e.g by possessing complement receptors which mediate attachment to, then infection of host macrophages, which are eventually destroyed. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-12-26 | Added | RELATION | is a GO:0052170 (symbiont-mediated suppression of host innate immune response) |
2023-12-26 | Deleted | RELATION | is a GO:0042783 (evasion of host immune response) |
2019-09-12 | Deleted | RELATION | is a GO:0051811 (active evasion of immune response of other organism via regulation of complement system of other organism involved in symbiotic interaction) |
2008-04-01 | Updated | RELATION | is a GO:0051811 (active evasion of immune response of other organism via regulation of complement system of other organism involved in symbiotic interaction) |
2008-04-01 | Updated | RELATION | is a GO:0042783 (evasion of host immune response) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-12-26 | Added | XREF | VZ:811 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:33090 (Viridiplantae) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4895 (Schizosaccharomyces) |
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:33208 (Metazoa) |
2019-09-12 | Added | SECONDARY | GO:0051811 (active evasion of immune response of other organism via regulation of complement system of other organism involved in symbiotic interaction) |
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