This term is obsolete.

GO:0043137 JSON

DNA replication, removal of RNA primer

Biological Process

Definition (GO:0043137 GONUTS page)

Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease. PMID:12424238

100,130 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
Okazaki initiator RNA removal exact

Ancestor Chart

Ancestor chart for GO:0043137
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0043137

Child Term Relationship to
GO:0043137
removal of RNA primer involved in mitotic DNA replication
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein D3ZVK1 10116 MCM8_RAT GO:0006260 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein F1M5F3 10116 MCM9_RAT GO:0006260 3 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein F1N2W9 9913 MCM9_BOVIN GO:0006260 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein O61847 6239 CDK2_CAEEL GO:0006260 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:10207147
NOT-qualified manual protein O94445 284812 SUV3_SCHPO GO:0006401 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:18304578
NOT-qualified manual protein Q1MTN7 284812 RPM1_SCHPO GO:0006401 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:18304578
NOT-qualified manual protein Q2KHI9 10090 MCM9_MOUSE GO:0006260 2 NOT-qualified manual annotations exist with evidence code ECO:0000315 from these references: PMID:21987787, PMID:23401855
NOT-qualified manual protein Q9NXL9 9606 MCM9_HUMAN GO:0006260 1 NOT-qualified manual annotation exists with evidence code ECO:0000316 from this reference: PMID:23401855
NOT-qualified manual protein Q9UJA3 9606 MCM8_HUMAN GO:0006260 1 NOT-qualified manual annotation exists with evidence code ECO:0000316 from this reference: PMID:23401855

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0043137 based on ALL annotations
The top 100 of 381 co-occurring terms
Co-occurring Term PR S% #Together #Compared
DNA replication, removal of RNA primer
1,949.11 100.00 100,014 100,014
ribonuclease H2 complex
1,702.95 49.16 52,930 60,581
RNA-DNA hybrid ribonuclease activity
706.71 35.45 94,072 259,451
RNA catabolic process
336.22 16.11 70,990 411,540
mismatch repair
336.79 14.98 52,930 306,322
manganese ion binding
155.52 7.04 37,576 470,951
5'-flap endonuclease activity
254.66 4.72 6,885 52,697
RNA metabolic process
183.93 4.52 7,990 84,670
endonuclease activity
85.91 4.40 97,160 2,204,272
5'-3' exonuclease activity
117.35 3.30 6,794 112,848
Totals 864560 109675815
No co-occurrence statistics for GO:0043137 based on MANUAL annotations
The top 100 of 104 co-occurring terms
Co-occurring Term PR S% #Together #Compared
DNA replication, removal of RNA primer
3,166.17 100.00 408 408
RNA-DNA hybrid ribonuclease activity
2,794.10 86.33 398 451
ribonuclease H2 complex
1,929.21 32.88 170 279
mismatch repair
375.98 10.20 171 1,440
site-specific endodeoxyribonuclease activity, specific for altered base
1,217.76 1.20 5 13
gamma DNA polymerase complex
931.23 1.19 5 17
DNA replication, Okazaki fragment processing
879.49 1.19 5 18
positive regulation of DNA replication
68.53 0.79 5 231
mitochondrial DNA replication
40.74 0.74 7 544
RNA-templated DNA biosynthetic process
1,055.39 0.72 3 9
Totals 1406 610517

Change Log

Timestamp Action Category Detail
2021-09-22 Added RELATION part of GO:0006260 (DNA replication)
2021-09-22 Deleted RELATION is a GO:0006259 (DNA metabolic process)
2018-10-05 Added RELATION has part GO:0006273 (lagging strand elongation)
2018-10-05 Added RELATION has part GO:0006272 (leading strand elongation)
2018-10-05 Deleted RELATION part of GO:0033567 (DNA replication, Okazaki fragment processing)
2008-05-13 Added DEFINITION Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.
2008-05-12 Deleted DEFINITION Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.
2008-04-01 Updated RELATION is a GO:0006401 (RNA catabolic process)
2008-04-01 Updated RELATION part of GO:0033567 (DNA replication, Okazaki fragment processing)
2008-04-01 Updated RELATION is a GO:0006259 (DNA metabolic process)
Timestamp Action Category Detail
2004-04-16 Added TERM DNA replication, removal of RNA primer
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.
2008-05-12 Deleted DEFINITION Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.
2007-08-09 Added SYNONYM Okazaki initiator RNA removal
2007-08-09 Deleted SYNONYM Okazaki initiator RNA removal
2007-08-05 Deleted SYNONYM Okazaki fragment processing
2005-03-26 Added SYNONYM Okazaki fragment processing
2004-04-19 Added SYNONYM Okazaki initiator RNA removal
2004-04-17 Added DEFINITION Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.
Timestamp Action Category Detail
2021-09-22 Added RELATION part of GO:0006260 (DNA replication)
2021-09-22 Deleted RELATION is a GO:0006259 (DNA metabolic process)
2018-10-05 Added RELATION has part GO:0006273 (lagging strand elongation)
2018-10-05 Added RELATION has part GO:0006272 (leading strand elongation)
2018-10-05 Deleted RELATION part of GO:0033567 (DNA replication, Okazaki fragment processing)
2008-04-01 Updated RELATION is a GO:0006401 (RNA catabolic process)
2008-04-01 Updated RELATION part of GO:0033567 (DNA replication, Okazaki fragment processing)
2008-04-01 Updated RELATION is a GO:0006259 (DNA metabolic process)
Timestamp Action Category Detail
Timestamp Action Category Detail
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