GO:0043137
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DNA replication, removal of RNA primer
Biological Process
Definition (GO:0043137 GONUTS page)
Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease. PMID:12424238
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
Okazaki initiator RNA removal | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0043137
Child Term | Relationship to GO:0043137 |
---|---|
removal of RNA primer involved in mitotic DNA replication
|
is_a |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | D3ZVK1 | 10116 | MCM8_RAT | GO:0006260 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | F1M5F3 | 10116 | MCM9_RAT | GO:0006260 | 3 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096 | |
NOT-qualified manual | protein | F1N2W9 | 9913 | MCM9_BOVIN | GO:0006260 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
NOT-qualified manual | protein | O61847 | 6239 | CDK2_CAEEL | GO:0006260 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:10207147 | |
NOT-qualified manual | protein | O94445 | 284812 | SUV3_SCHPO | GO:0006401 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:18304578 | |
NOT-qualified manual | protein | Q1MTN7 | 284812 | RPM1_SCHPO | GO:0006401 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:18304578 | |
NOT-qualified manual | protein | Q2KHI9 | 10090 | MCM9_MOUSE | GO:0006260 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000315 from these references: PMID:21987787, PMID:23401855 | |
NOT-qualified manual | protein | Q9NXL9 | 9606 | MCM9_HUMAN | GO:0006260 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000316 from this reference: PMID:23401855 | |
NOT-qualified manual | protein | Q9UJA3 | 9606 | MCM8_HUMAN | GO:0006260 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000316 from this reference: PMID:23401855 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0043137 based on ALL annotations
The top 100 of 381 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
DNA replication, removal of RNA primer
|
1,949.11 | 100.00 | 100,014 | 100,014 |
ribonuclease H2 complex
|
1,702.95 | 49.16 | 52,930 | 60,581 |
RNA-DNA hybrid ribonuclease activity
|
706.71 | 35.45 | 94,072 | 259,451 |
RNA catabolic process
|
336.22 | 16.11 | 70,990 | 411,540 |
mismatch repair
|
336.79 | 14.98 | 52,930 | 306,322 |
manganese ion binding
|
155.52 | 7.04 | 37,576 | 470,951 |
5'-flap endonuclease activity
|
254.66 | 4.72 | 6,885 | 52,697 |
RNA metabolic process
|
183.93 | 4.52 | 7,990 | 84,670 |
endonuclease activity
|
85.91 | 4.40 | 97,160 | 2,204,272 |
5'-3' exonuclease activity
|
117.35 | 3.30 | 6,794 | 112,848 |
Totals | 864560 | 109675815 |
No co-occurrence statistics for GO:0043137 based on MANUAL annotations
The top 100 of 104 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
DNA replication, removal of RNA primer
|
3,166.17 | 100.00 | 408 | 408 |
RNA-DNA hybrid ribonuclease activity
|
2,794.10 | 86.33 | 398 | 451 |
ribonuclease H2 complex
|
1,929.21 | 32.88 | 170 | 279 |
mismatch repair
|
375.98 | 10.20 | 171 | 1,440 |
site-specific endodeoxyribonuclease activity, specific for altered base
|
1,217.76 | 1.20 | 5 | 13 |
gamma DNA polymerase complex
|
931.23 | 1.19 | 5 | 17 |
DNA replication, Okazaki fragment processing
|
879.49 | 1.19 | 5 | 18 |
positive regulation of DNA replication
|
68.53 | 0.79 | 5 | 231 |
mitochondrial DNA replication
|
40.74 | 0.74 | 7 | 544 |
RNA-templated DNA biosynthetic process
|
1,055.39 | 0.72 | 3 | 9 |
Totals | 1406 | 610517 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-09-22 | Added | RELATION | part of GO:0006260 (DNA replication) |
2021-09-22 | Deleted | RELATION | is a GO:0006259 (DNA metabolic process) |
2018-10-05 | Added | RELATION | has part GO:0006273 (lagging strand elongation) |
2018-10-05 | Added | RELATION | has part GO:0006272 (leading strand elongation) |
2018-10-05 | Deleted | RELATION | part of GO:0033567 (DNA replication, Okazaki fragment processing) |
2008-05-13 | Added | DEFINITION | Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease. |
2008-05-12 | Deleted | DEFINITION | Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease. |
2008-04-01 | Updated | RELATION | is a GO:0006401 (RNA catabolic process) |
2008-04-01 | Updated | RELATION | part of GO:0033567 (DNA replication, Okazaki fragment processing) |
2008-04-01 | Updated | RELATION | is a GO:0006259 (DNA metabolic process) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2004-04-16 | Added | TERM | DNA replication, removal of RNA primer |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease. |
2008-05-12 | Deleted | DEFINITION | Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease. |
2007-08-09 | Added | SYNONYM | Okazaki initiator RNA removal |
2007-08-09 | Deleted | SYNONYM | Okazaki initiator RNA removal |
2007-08-05 | Deleted | SYNONYM | Okazaki fragment processing |
2005-03-26 | Added | SYNONYM | Okazaki fragment processing |
2004-04-19 | Added | SYNONYM | Okazaki initiator RNA removal |
2004-04-17 | Added | DEFINITION | Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-09-22 | Added | RELATION | part of GO:0006260 (DNA replication) |
2021-09-22 | Deleted | RELATION | is a GO:0006259 (DNA metabolic process) |
2018-10-05 | Added | RELATION | has part GO:0006273 (lagging strand elongation) |
2018-10-05 | Added | RELATION | has part GO:0006272 (leading strand elongation) |
2018-10-05 | Deleted | RELATION | part of GO:0033567 (DNA replication, Okazaki fragment processing) |
2008-04-01 | Updated | RELATION | is a GO:0006401 (RNA catabolic process) |
2008-04-01 | Updated | RELATION | part of GO:0033567 (DNA replication, Okazaki fragment processing) |
2008-04-01 | Updated | RELATION | is a GO:0006259 (DNA metabolic process) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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