This term is obsolete.

GO:0043137 JSON

DNA replication, removal of RNA primer

Biological Process

Definition (GO:0043137 GONUTS page)

Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease. PMID:12424238

101,816 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
Okazaki initiator RNA removal exact

Ancestor Chart

Ancestor chart for GO:0043137
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Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0043137

Child Term Relationship to
GO:0043137
GO:1903469
removal of RNA primer involved in mitotic DNA replication
is_a

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein D3ZVK1 10116 MCM8_RAT GO:0006260 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein F1M5F3 10116 MCM9_RAT GO:0006260 3 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein F1N2W9 9913 MCM9_BOVIN GO:0006260 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein O61847 6239 CDK2_CAEEL GO:0006260 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:10207147
NOT-qualified manual protein O94445 284812 SUV3_SCHPO GO:0006401 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:18304578
NOT-qualified manual protein Q1MTN7 284812 RPM1_SCHPO GO:0006401 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:18304578
NOT-qualified manual protein Q2KHI9 10090 MCM9_MOUSE GO:0006260 2 NOT-qualified manual annotations exist with evidence code ECO:0000315 from these references: PMID:21987787, PMID:23401855
NOT-qualified manual protein Q9NXL9 9606 MCM9_HUMAN GO:0006260 1 NOT-qualified manual annotation exists with evidence code ECO:0000316 from this reference: PMID:23401855
NOT-qualified manual protein Q9UJA3 9606 MCM8_HUMAN GO:0006260 1 NOT-qualified manual annotation exists with evidence code ECO:0000316 from this reference: PMID:23401855

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0043137 based on ALL annotations
The top 100 of 371 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0043137
DNA replication, removal of RNA primer
1,948.54 100.00 101,694 101,694
GO:0032299
ribonuclease H2 complex
1,698.17 48.97 53,671 61,584
GO:0004523
RNA-DNA hybrid ribonuclease activity
681.71 34.24 95,701 273,545
GO:0006401
RNA catabolic process
337.18 16.15 71,970 415,912
GO:0006298
mismatch repair
335.74 14.93 53,671 311,488
GO:0030145
manganese ion binding
154.18 6.99 38,041 480,768
GO:0017108
5'-flap endonuclease activity
254.90 4.71 6,969 53,274
GO:0004519
endonuclease activity
86.63 4.44 100,236 2,254,459
GO:0016070
RNA metabolic process
168.24 4.35 8,184 94,787
GO:0008409
5'-3' exonuclease activity
116.78 3.28 6,878 114,765
Totals 888742 109019636
No co-occurrence statistics for GO:0043137 based on MANUAL annotations
The top 100 of 100 co-occurring terms
Co-occurring Term PR S% #Together #Compared
GO:0043137
DNA replication, removal of RNA primer
3,520.03 100.00 401 401
GO:0004523
RNA-DNA hybrid ribonuclease activity
3,065.33 85.19 391 449
GO:0032299
ribonuclease H2 complex
2,109.61 33.78 175 292
GO:0006298
mismatch repair
408.66 10.11 176 1,516
GO:0016890
site-specific endodeoxyribonuclease activity, specific for altered base
1,353.86 1.22 5 13
GO:0005760
gamma DNA polymerase complex
1,035.30 1.21 5 17
GO:0033567
DNA replication, Okazaki fragment processing
977.79 1.21 5 18
GO:0006264
mitochondrial DNA replication
78.72 0.99 7 313
GO:0045740
positive regulation of DNA replication
70.12 0.77 5 251
GO:0006278
RNA-templated DNA biosynthetic process
1,173.34 0.74 3 9
Totals 1406 975860

Change Log

Timestamp Action Category Detail
2021-09-22 Deleted RELATION is a GO:0006259 (DNA metabolic process)
2021-09-22 Added RELATION part of GO:0006260 (DNA replication)
2018-10-05 Deleted RELATION part of GO:0033567 (DNA replication, Okazaki fragment processing)
2018-10-05 Added RELATION has part GO:0006272 (leading strand elongation)
2018-10-05 Added RELATION has part GO:0006273 (lagging strand elongation)
2008-05-13 Added DEFINITION Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.
2008-05-12 Deleted DEFINITION Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.
2008-04-01 Updated RELATION is a GO:0006401 (RNA catabolic process)
2008-04-01 Updated RELATION part of GO:0033567 (DNA replication, Okazaki fragment processing)
2008-04-01 Updated RELATION is a GO:0006259 (DNA metabolic process)
Timestamp Action Category Detail
2004-04-16 Added TERM DNA replication, removal of RNA primer
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.
2008-05-12 Deleted DEFINITION Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.
2007-08-09 Deleted SYNONYM Okazaki initiator RNA removal
2007-08-09 Added SYNONYM Okazaki initiator RNA removal
2007-08-05 Deleted SYNONYM Okazaki fragment processing
2005-03-26 Added SYNONYM Okazaki fragment processing
2004-04-19 Added SYNONYM Okazaki initiator RNA removal
2004-04-17 Added DEFINITION Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.
Timestamp Action Category Detail
2021-09-22 Deleted RELATION is a GO:0006259 (DNA metabolic process)
2021-09-22 Added RELATION part of GO:0006260 (DNA replication)
2018-10-05 Deleted RELATION part of GO:0033567 (DNA replication, Okazaki fragment processing)
2018-10-05 Added RELATION has part GO:0006272 (leading strand elongation)
2018-10-05 Added RELATION has part GO:0006273 (lagging strand elongation)
2008-04-01 Updated RELATION is a GO:0006401 (RNA catabolic process)
2008-04-01 Updated RELATION part of GO:0033567 (DNA replication, Okazaki fragment processing)
2008-04-01 Updated RELATION is a GO:0006259 (DNA metabolic process)
Timestamp Action Category Detail
Timestamp Action Category Detail
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