This term is obsolete.

GO:0043184 JSON

vascular endothelial growth factor receptor 2 binding

Molecular Function

Definition (GO:0043184 GONUTS page)

Binding to a vascular endothelial growth factor receptor 2.

2,369 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
kinase domain region binding exact
VEGFR 2 binding exact
VEGF receptor 2 binding exact
Flk-1 binding exact
KDR binding broad

Ancestor Chart

Ancestor chart for GO:0043184
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A8XY28 6238 A8XY28_CAEBR GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PL19 6945 B7PL19_IXOSC GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PVH4 6945 B7PVH4_IXOSC GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O16262 6239 NIPI4_CAEEL GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O35251 10116 VEGFD_RAT GO:0043184 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein O95970 9606 LGI1_HUMAN GO:0005102 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20463223
NOT-qualified manual protein P21333-1 9606 FLNA_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684
NOT-qualified manual protein P63026 9913 VAMP2_BOVIN GO:0005515 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699
NOT-qualified manual protein P97946 10090 VEGFD_MOUSE GO:0043184 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:11136737
NOT-qualified manual protein Q86V48 9606 LUZP1_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0043184 based on ALL annotations
The top 100 of 528 co-occurring terms
Co-occurring Term PR S% #Together #Compared
vascular endothelial growth factor receptor 2 binding
83,485.56 100.00 2,335 2,335
regulation of wound healing
63,387.19 34.41 902 1,188
regulation of Rac protein signal transduction
13,701.60 13.02 902 5,496
cell-cell contact zone
13,285.81 12.70 902 5,668
vascular endothelial growth factor receptor 1 binding
82,957.17 6.72 157 158
vascular endothelial growth factor receptor-2 signaling pathway
28,048.51 6.36 170 506
negative regulation of vascular endothelial growth factor signaling pathway
11,654.26 4.80 159 1,139
positive regulation of protein-containing complex assembly
6,166.55 4.74 273 3,696
transmembrane receptor protein tyrosine kinase activator activity
8,250.58 4.22 160 1,619
fibrinogen binding
6,840.67 4.21 186 2,270
Totals 14401 103224
No co-occurrence statistics for GO:0043184 based on MANUAL annotations
The top 100 of 489 co-occurring terms
Co-occurring Term PR S% #Together #Compared
vascular endothelial growth factor receptor 2 binding
16,561.53 100.00 78 78
vascular endothelial growth factor receptor 1 binding
15,772.88 25.32 20 21
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
12,241.13 20.24 17 23
regulation of wound healing
7,270.91 17.82 18 41
endothelial cell chemotaxis
6,624.61 17.14 18 45
positive regulation of positive chemotaxis
6,480.60 16.98 18 46
cell migration involved in sprouting angiogenesis
3,739.70 14.00 21 93
vascular endothelial growth factor receptor binding
3,347.54 12.42 19 94
monocyte differentiation
3,275.91 11.92 18 91
platelet-derived growth factor receptor binding
2,608.11 10.81 20 127
Totals 841 10343

Change Log

Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with vascular endothelial growth factor receptor 2.
2021-05-24 Added DEFINITION Binding to a vascular endothelial growth factor receptor 2.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with vascular endothelial growth factor receptor 2.
2009-07-03 Deleted DEFINITION Interacting selectively with vascular endothelial growth factor receptor 2.
2008-05-13 Added DEFINITION Interacting selectively with vascular endothelial growth factor receptor 2.
2008-05-12 Deleted DEFINITION Interacting selectively with vascular endothelial growth factor receptor 2.
2008-04-01 Updated RELATION is a GO:0005172 (vascular endothelial growth factor receptor binding)
2007-08-09 Deleted SYNONYM kinase domain region binding
2007-08-09 Deleted SYNONYM VEGFR 2 binding
2007-08-09 Deleted SYNONYM VEGF receptor 2 binding
Timestamp Action Category Detail
2004-07-22 Added TERM vascular endothelial growth factor receptor 2 binding
Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with vascular endothelial growth factor receptor 2.
2021-05-24 Added DEFINITION Binding to a vascular endothelial growth factor receptor 2.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with vascular endothelial growth factor receptor 2.
2009-07-03 Deleted DEFINITION Interacting selectively with vascular endothelial growth factor receptor 2.
2008-05-13 Added DEFINITION Interacting selectively with vascular endothelial growth factor receptor 2.
2008-05-12 Deleted DEFINITION Interacting selectively with vascular endothelial growth factor receptor 2.
2007-08-09 Deleted SYNONYM kinase domain region binding
2007-08-09 Deleted SYNONYM VEGFR 2 binding
2007-08-09 Deleted SYNONYM VEGF receptor 2 binding
2007-08-09 Deleted SYNONYM KDR binding
2007-08-09 Deleted SYNONYM Flk-1 binding
2007-08-09 Added SYNONYM VEGFR 2 binding
2007-08-09 Added SYNONYM VEGF receptor 2 binding
2007-08-09 Added SYNONYM kinase domain region binding
2007-08-09 Added SYNONYM Flk-1 binding
2007-08-09 Added SYNONYM KDR binding
2004-07-22 Added DEFINITION Interacting selectively with vascular endothelial growth factor receptor 2.
2004-07-22 Added SYNONYM VEGF receptor 2 binding
2004-07-22 Added SYNONYM VEGFR 2 binding
2004-07-22 Added SYNONYM Flk-1 binding
2004-07-22 Added SYNONYM KDR binding
2004-07-22 Added SYNONYM kinase domain region binding
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0005172 (vascular endothelial growth factor receptor binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
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