GO:0043405
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regulation of MAP kinase activity
Biological Process
Definition (GO:0043405 GONUTS page)
Any process that modulates the frequency, rate or extent of MAP kinase activity.
Restrictions
This term should not be used for direct annotation.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
Regulation of MAPK activity | exact |
regulation of mitogen activated protein kinase activity | exact |
regulation of mitogen-activated protein kinase activity | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0043405
Child Term | Relationship to GO:0043405 |
---|---|
positive regulation of MAP kinase activity
|
is_a |
negative regulation of MAP kinase activity
|
is_a |
regulation of JUN kinase activity
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Describing enzyme functions that catalyse multi-stage reactions | Link |
GO Discussions
The GO editorial group is intending to improve the information provided in this area of the GO. If you would like to be involved in discussions regarding this development activity, please email the GO Consortium. Please note that it is still appropriate to use this term for curation or analysis purpose:
Ontology Development Project | |
---|---|
signalling | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | C8VKG6 | 227321 | C8VKG6_EMENI | GO:0019220 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:14668368 | |
NOT-qualified manual | protein | O43320 | 9606 | FGF16_HUMAN | GO:0043405 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:16756958 | |
NOT-qualified manual | protein | Q96H20 | 9606 | SNF8_HUMAN | GO:0043405 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:17714434 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0043405 based on ALL annotations
The top 100 of 195 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
regulation of MAP kinase activity
|
9,007,039.00 | 100.00 | 22 | 22 |
positive regulation of ubiquitin-protein transferase activity
|
1,501,173.20 | 9.52 | 4 | 24 |
negative regulation of protein kinase activity
|
369,140.97 | 3.60 | 5 | 122 |
phagocytic vesicle lumen
|
1,286,720.00 | 3.57 | 1 | 7 |
nuclear cyclin-dependent protein kinase holoenzyme complex
|
303,608.06 | 3.09 | 6 | 178 |
positive regulation of protein binding
|
310,587.60 | 2.56 | 2 | 58 |
ubiquitin-protein transferase regulator activity
|
235,170.73 | 2.53 | 10 | 383 |
negative regulation of DNA-binding transcription factor activity
|
214,453.33 | 2.07 | 3 | 126 |
negative regulation of epidermal growth factor-activated receptor activity
|
290,549.66 | 1.92 | 1 | 31 |
cyclin K-CDK12 complex
|
186,674.39 | 1.90 | 4 | 193 |
Totals | 335 | 1758197 |
No co-occurrence statistics for GO:0043405 based on MANUAL annotations
The top 100 of 143 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
regulation of MAP kinase activity
|
64,160.59 | 100.00 | 22 | 22 |
ubiquitin-protein transferase regulator activity
|
20,414.73 | 18.92 | 7 | 22 |
nuclear cyclin-dependent protein kinase holoenzyme complex
|
17,498.34 | 15.79 | 6 | 22 |
cyclin K-CDK12 complex
|
24,060.22 | 11.11 | 3 | 8 |
positive regulation of ubiquitin-protein transferase activity
|
10,693.43 | 9.52 | 4 | 24 |
regulation of D-glucose transmembrane transport
|
6,874.35 | 6.38 | 3 | 28 |
mitogen-activated protein kinase kinase binding
|
3,742.70 | 5.19 | 7 | 120 |
positive regulation of exosomal secretion
|
4,694.68 | 5.00 | 3 | 41 |
positive regulation of viral budding via host ESCRT complex
|
12,832.12 | 3.85 | 1 | 5 |
positive regulation of eosinophil differentiation
|
10,693.43 | 3.70 | 1 | 6 |
Totals | 264 | 75939 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-26 | Added | SUBSET | gocheck_obsoletion_candidate |
2024-07-26 | Deleted | SUBSET | gocheck_do_not_annotate |
2023-06-13 | Added | SUBSET | gocheck_do_not_annotate |
2020-10-08 | Deleted | RELATION | is a GO:0043408 (regulation of MAPK cascade) |
2012-10-29 | Added | RELATION | is a GO:0043408 (regulation of MAPK cascade) |
2012-10-29 | Deleted | RELATION | is a GO:0009966 (regulation of signal transduction) |
2011-01-16 | Deleted | RELATION | is a GO:0035466 (regulation of signaling pathway) |
2010-09-17 | Deleted | RELATION | is a GO:0045859 (regulation of protein kinase activity) |
2010-09-17 | Added | RELATION | is a GO:0071900 (regulation of protein serine/threonine kinase activity) |
2010-06-15 | Added | RELATION | regulates GO:0004707 (MAP kinase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2009-02-25 | Updated | TERM | regulation of MAP kinase activity |
2009-02-22 | Updated | TERM | regulation of MAP kinase activity |
2007-10-12 | Updated | TERM | regulation of MAP kinase activity |
2005-07-04 | Added | TERM | regulation of MAPK activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | Any process that modulates the frequency, rate or extent of MAP kinase activity. |
2008-05-12 | Deleted | DEFINITION | Any process that modulates the frequency, rate or extent of MAP kinase activity. |
2008-04-05 | Deleted | SYNONYM | regulation of MAP kinase activity |
2007-10-12 | Added | SYNONYM | Regulation of MAPK activity |
2007-08-09 | Added | SYNONYM | regulation of mitogen-activated protein kinase activity |
2007-08-09 | Added | SYNONYM | regulation of mitogen activated protein kinase activity |
2007-08-09 | Deleted | SYNONYM | regulation of mitogen activated protein kinase activity |
2007-08-09 | Added | SYNONYM | regulation of MAP kinase activity |
2007-08-09 | Deleted | SYNONYM | regulation of MAP kinase activity |
2007-08-09 | Deleted | SYNONYM | regulation of mitogen-activated protein kinase activity |
2005-07-04 | Added | DEFINITION | Any process that modulates the frequency, rate or extent of MAP kinase activity. |
2005-07-04 | Added | SYNONYM | regulation of mitogen activated protein kinase activity |
2005-07-04 | Added | SYNONYM | regulation of MAP kinase activity |
2005-07-04 | Added | SYNONYM | regulation of mitogen-activated protein kinase activity |
Timestamp | Action | Category | Detail |
---|---|---|---|
2020-10-08 | Deleted | RELATION | is a GO:0043408 (regulation of MAPK cascade) |
2012-10-29 | Added | RELATION | is a GO:0043408 (regulation of MAPK cascade) |
2012-10-29 | Deleted | RELATION | is a GO:0009966 (regulation of signal transduction) |
2011-01-16 | Deleted | RELATION | is a GO:0035466 (regulation of signaling pathway) |
2010-09-17 | Deleted | RELATION | is a GO:0045859 (regulation of protein kinase activity) |
2010-09-17 | Added | RELATION | is a GO:0071900 (regulation of protein serine/threonine kinase activity) |
2010-06-15 | Added | RELATION | regulates GO:0004707 (MAP kinase activity) |
2010-06-14 | Deleted | RELATION | regulates GO:0004707 (MAP kinase activity) |
2010-06-08 | Added | RELATION | regulates GO:0004707 (MAP kinase activity) |
2010-05-13 | Added | RELATION | is a GO:0009966 (regulation of signal transduction) |
2010-04-21 | Deleted | RELATION | is a GO:0009966 (regulation of signal transduction) |
2010-04-21 | Added | RELATION | is a GO:0035466 (regulation of signaling pathway) |
2009-10-27 | Added | RELATION | is a GO:0009966 (regulation of signal transduction) |
2009-02-25 | Deleted | RELATION | regulates GO:0004707 (MAP kinase activity) |
2009-02-22 | Added | RELATION | regulates GO:0004707 (MAP kinase activity) |
2008-04-01 | Updated | RELATION | is a GO:0045859 (regulation of protein kinase activity) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-07-26 | Added | SUBSET | gocheck_obsoletion_candidate |
2024-07-26 | Deleted | SUBSET | gocheck_do_not_annotate |
2023-06-13 | Added | SUBSET | gocheck_do_not_annotate |
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