This term is obsolete.
Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and an inhibin alpha subunit. See also the cellular component term 'inhibin complex ; GO:0043511'.

GO:0043509 JSON

activin A complex

Cellular Component

Definition (GO:0043509 GONUTS page)

A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A).

Comments

Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and an inhibin alpha subunit. See also the cellular component term 'inhibin complex ; GO:0043511'.

Secondary IDs

GO:0048181

121 annotations

Ancestor Chart

Ancestor chart for GO:0043509
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Ancestor chart

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
IEA Review protein Q99470 9606 SDF2_HUMAN GO:0005576 Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. IPR016093|IPR036300
NOT-qualified manual protein A0A0G2JY81 10116 A0A0G2JY81_RAT GO:0005615 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A7U3L4H9 10116 A0A7U3L4H9_RAT GO:0005576 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A8I6AAN5 10116 A0A8I6AAN5_RAT GO:0005615 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A1Z7L0 7227 A1Z7L0_DROME GO:0005615 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:35714143
NOT-qualified manual protein A4QNU9 7955 A4QNU9_DANRE GO:0005615 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:22292055
NOT-qualified manual protein A6HTD8 10116 A6HTD8_RAT GO:0005615 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6HWX9 10116 A6HWX9_RAT GO:0005615 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K8X7 10116 A6K8X7_RAT GO:0005576 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein B1WC21 10116 B1WC21_RAT GO:0005615 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0043509 based on ALL annotations
The top 82 of 82 co-occurring terms
Co-occurring Term PR S% #Together #Compared
activin A complex
1,769,239.90 100.00 112 112
regulation of follicle-stimulating hormone secretion
1,738,200.60 98.25 112 114
androst-4-ene-3,17-dione biosynthetic process
1,098,148.90 53.89 90 145
progesterone secretion
952,667.56 53.85 112 208
inhibin A complex
921,650.56 52.09 112 215
striatal medium spiny neuron differentiation
762,355.44 42.06 106 246
negative regulation of hair follicle development
668,238.06 36.84 105 278
positive regulation of ovulation
701,595.20 36.51 92 232
enzyme activator complex
618,942.00 34.30 106 303
testosterone biosynthetic process
438,654.50 23.38 90 363
Totals 5451 12200682
No co-occurrence statistics for GO:0043509 based on MANUAL annotations
The top 81 of 81 co-occurring terms
Co-occurring Term PR S% #Together #Compared
activin A complex
108,579.45 100.00 13 13
inhibin A complex
94,102.20 86.67 13 15
regulation of follicle-stimulating hormone secretion
94,102.20 86.67 13 15
progesterone secretion
74,291.21 68.42 13 19
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
27,677.12 25.49 13 51
positive regulation of ovulation
28,954.52 22.86 8 30
enzyme activator complex
54,289.73 13.33 2 4
hemoglobin biosynthetic process
13,704.20 12.62 13 103
androst-4-ene-3,17-dione biosynthetic process
43,431.79 12.50 2 5
negative regulation of hair follicle development
31,022.71 11.11 2 7
Totals 384 227550

Change Log

Timestamp Action Category Detail
2008-05-13 Added DEFINITION A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A).
2008-05-12 Deleted DEFINITION A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A).
2008-04-01 Updated RELATION is a GO:0048180 (activin complex)
2007-01-15 Added SECONDARY GO:0048181 (activin A complex)
2005-10-28 Added DEFINITION A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A).
2005-10-28 Added TERM activin A complex
Timestamp Action Category Detail
2005-10-28 Added TERM activin A complex
Timestamp Action Category Detail
2008-05-13 Added DEFINITION A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A).
2008-05-12 Deleted DEFINITION A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A).
2005-10-28 Added DEFINITION A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A).
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0048180 (activin complex)
Timestamp Action Category Detail
Timestamp Action Category Detail
2007-01-15 Added SECONDARY GO:0048181 (activin A complex)
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