Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and an inhibin alpha subunit. See also the cellular component term 'inhibin complex ; GO:0043511'.
GO:0043509
JSON
activin A complex
Cellular Component
Definition (GO:0043509 GONUTS page)
A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A).
Comments
Note that the actions of the activin complex are the opposite of those of the inhibin complex, which is a dimer of an inhibin beta-A or inhibin beta-B subunit and an inhibin alpha subunit. See also the cellular component term 'inhibin complex ; GO:0043511'.
Secondary IDs
GO:0048181
Ancestor Chart
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q99470 | 9606 | SDF2_HUMAN | GO:0005576 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | A0A0G2JY81 | 10116 | A0A0G2JY81_RAT | GO:0005615 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A7U3L4H9 | 10116 | A0A7U3L4H9_RAT | GO:0005576 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A8I6AAN5 | 10116 | A0A8I6AAN5_RAT | GO:0005615 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A1Z7L0 | 7227 | A1Z7L0_DROME | GO:0005615 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:35714143 | |
NOT-qualified manual | protein | A4QNU9 | 7955 | A4QNU9_DANRE | GO:0005615 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:22292055 | |
NOT-qualified manual | protein | A6HTD8 | 10116 | A6HTD8_RAT | GO:0005615 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6HWX9 | 10116 | A6HWX9_RAT | GO:0005615 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A6K8X7 | 10116 | A6K8X7_RAT | GO:0005576 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | B1WC21 | 10116 | B1WC21_RAT | GO:0005615 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0043509 based on ALL annotations
The top 82 of 82 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
activin A complex
|
1,769,239.90 | 100.00 | 112 | 112 |
regulation of follicle-stimulating hormone secretion
|
1,738,200.60 | 98.25 | 112 | 114 |
androst-4-ene-3,17-dione biosynthetic process
|
1,098,148.90 | 53.89 | 90 | 145 |
progesterone secretion
|
952,667.56 | 53.85 | 112 | 208 |
inhibin A complex
|
921,650.56 | 52.09 | 112 | 215 |
striatal medium spiny neuron differentiation
|
762,355.44 | 42.06 | 106 | 246 |
negative regulation of hair follicle development
|
668,238.06 | 36.84 | 105 | 278 |
positive regulation of ovulation
|
701,595.20 | 36.51 | 92 | 232 |
enzyme activator complex
|
618,942.00 | 34.30 | 106 | 303 |
testosterone biosynthetic process
|
438,654.50 | 23.38 | 90 | 363 |
Totals | 5451 | 12200682 |
No co-occurrence statistics for GO:0043509 based on MANUAL annotations
The top 81 of 81 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
activin A complex
|
108,579.45 | 100.00 | 13 | 13 |
inhibin A complex
|
94,102.20 | 86.67 | 13 | 15 |
regulation of follicle-stimulating hormone secretion
|
94,102.20 | 86.67 | 13 | 15 |
progesterone secretion
|
74,291.21 | 68.42 | 13 | 19 |
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
27,677.12 | 25.49 | 13 | 51 |
positive regulation of ovulation
|
28,954.52 | 22.86 | 8 | 30 |
enzyme activator complex
|
54,289.73 | 13.33 | 2 | 4 |
hemoglobin biosynthetic process
|
13,704.20 | 12.62 | 13 | 103 |
androst-4-ene-3,17-dione biosynthetic process
|
43,431.79 | 12.50 | 2 | 5 |
negative regulation of hair follicle development
|
31,022.71 | 11.11 | 2 | 7 |
Totals | 384 | 227550 |
Change Log
- All changes
- All changes
- Term
- Term
- Definition / Synonyms
- Definition / Synonyms
- Relationships
- Relationships
- Cross-references
- Cross-references
- Other
- Other
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A). |
2008-05-12 | Deleted | DEFINITION | A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A). |
2008-04-01 | Updated | RELATION | is a GO:0048180 (activin complex) |
2007-01-15 | Added | SECONDARY | GO:0048181 (activin A complex) |
2005-10-28 | Added | DEFINITION | A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A). |
2005-10-28 | Added | TERM | activin A complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2005-10-28 | Added | TERM | activin A complex |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A). |
2008-05-12 | Deleted | DEFINITION | A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A). |
2005-10-28 | Added | DEFINITION | A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A). |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0048180 (activin complex) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2007-01-15 | Added | SECONDARY | GO:0048181 (activin A complex) |
Not found :(
Sorry, but the Term you were trying to view does not exist.
Reported error:
It looks like this may have been caused by:
- a mistyped URL
- an out-of-date link