GO:0043589
JSON
skin morphogenesis
Biological Process
Definition (GO:0043589 GONUTS page)
The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
Ancestor Chart
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0043589 | skin morphogenesis | Only in Taxon | 7711 | Chordata |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A6KFG0 | 10116 | A6KFG0_RAT | GO:0043589 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | D4A7J3 | 10116 | D4A7J3_RAT | GO:0043589 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | E9Q876 | 10090 | ABCAC_MOUSE | GO:0043589 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27551807 | |
NOT-qualified manual | protein | Q86UK0 | 9606 | ABCAC_HUMAN | GO:0043589 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 |
Cross-references
Database | ID | Description |
---|---|---|
InterPro | IPR026087 | Corneodesmosin |
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0033561 | obsolete regulation of water loss via skin | consider GO:0043589 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0043589 based on ALL annotations
The top 100 of 741 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
skin morphogenesis
|
164,505.30 | 100.00 | 1,185 | 1,185 |
collagen type I trimer
|
110,069.00 | 14.42 | 184 | 275 |
nail development
|
57,531.91 | 12.45 | 192 | 549 |
positive regulation of L-glutamate import across plasma membrane
|
102,446.41 | 8.33 | 104 | 167 |
serum response element binding
|
152,089.81 | 8.21 | 98 | 106 |
contractile actin filament bundle assembly
|
138,978.61 | 8.15 | 98 | 116 |
Cajal-Retzius cell differentiation
|
86,406.83 | 8.13 | 104 | 198 |
ectoderm and mesoderm interaction
|
159,520.30 | 8.08 | 96 | 99 |
epidermal cell division
|
153,325.33 | 8.05 | 96 | 103 |
integrin alpha6-beta1 complex
|
86,010.38 | 8.05 | 103 | 197 |
Totals | 11578 | 92978 |
No co-occurrence statistics for GO:0043589 based on MANUAL annotations
The top 100 of 635 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
skin morphogenesis
|
23,487.25 | 100.00 | 55 | 55 |
nail development
|
11,743.63 | 17.91 | 12 | 24 |
integrin alpha6-beta1 complex
|
19,572.71 | 17.54 | 10 | 12 |
integrin alpha6-beta4 complex
|
23,487.25 | 16.36 | 9 | 9 |
lymphoid lineage cell migration
|
15,098.95 | 15.00 | 9 | 14 |
corneocyte desquamation
|
23,487.25 | 14.55 | 8 | 8 |
ectodermal cell differentiation
|
9,033.56 | 14.08 | 10 | 26 |
neuregulin binding
|
6,405.61 | 13.79 | 12 | 44 |
negative regulation of cornification
|
23,487.25 | 7.27 | 4 | 4 |
epidermal lamellar body membrane
|
23,487.25 | 7.27 | 4 | 4 |
Totals | 524 | 5587 |
Change Log
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- Definition / Synonyms
- Definition / Synonyms
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:7711 (Chordata) |
2013-06-28 | Added | RELATION | is a GO:0009887 (animal organ morphogenesis) |
2013-06-28 | Deleted | RELATION | is a GO:0048730 (epidermis morphogenesis) |
2010-12-03 | Deleted | DEFINITION | The process by which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. |
2010-12-03 | Added | DEFINITION | The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. |
2010-12-01 | Deleted | DEFINITION | The process by which the anatomical structures of the skin are generated and organized. Morphogenesis pertains to the creation of form. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. |
2010-12-01 | Added | DEFINITION | The process by which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. |
2008-05-13 | Added | DEFINITION | The process by which the anatomical structures of the skin are generated and organized. Morphogenesis pertains to the creation of form. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. |
2008-05-12 | Deleted | DEFINITION | The process by which the anatomical structures of the skin are generated and organized. Morphogenesis pertains to the creation of form. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. |
2008-04-01 | Updated | RELATION | is a GO:0048730 (epidermis morphogenesis) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2005-12-23 | Added | TERM | skin morphogenesis |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-12-03 | Deleted | DEFINITION | The process by which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. |
2010-12-03 | Added | DEFINITION | The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. |
2010-12-01 | Deleted | DEFINITION | The process by which the anatomical structures of the skin are generated and organized. Morphogenesis pertains to the creation of form. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. |
2010-12-01 | Added | DEFINITION | The process by which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. |
2008-05-13 | Added | DEFINITION | The process by which the anatomical structures of the skin are generated and organized. Morphogenesis pertains to the creation of form. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. |
2008-05-12 | Deleted | DEFINITION | The process by which the anatomical structures of the skin are generated and organized. Morphogenesis pertains to the creation of form. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. |
2005-12-23 | Added | DEFINITION | The process by which the anatomical structures of the skin are generated and organized. Morphogenesis pertains to the creation of form. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-06-28 | Added | RELATION | is a GO:0009887 (animal organ morphogenesis) |
2013-06-28 | Deleted | RELATION | is a GO:0048730 (epidermis morphogenesis) |
2008-04-01 | Updated | RELATION | is a GO:0048730 (epidermis morphogenesis) |
2008-04-01 | Updated | RELATION | part of GO:0043588 (skin development) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-03-05 | Added | CONSTRAINT | in_taxon NCBITaxon:7711 (Chordata) |
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