GO:0043651
JSON
linoleic acid metabolic process
Biological Process
Definition (GO:0043651 GONUTS page)
The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
| Synonym | Type |
|---|---|
| linoleic acid metabolism | exact |
Ancestor Chart
Ancestor chart for GO:0043651
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
| Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
|---|---|---|---|---|---|---|---|
| NOT-qualified manual | protein | F1LN46 | 10116 | CPT1C_RAT | GO:0006631 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:24222496 | |
| NOT-qualified manual | protein | F1LQ70 | 10116 | LOX12_RAT | GO:0043651 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
| NOT-qualified manual | protein | P18054 | 9606 | LOX12_HUMAN | GO:0043651 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:1851637 | |
| NOT-qualified manual | protein | Q8BGD5 | 10090 | CPT1C_MOUSE | GO:0006631 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 | |
| NOT-qualified manual | protein | Q8TCG5 | 9606 | CPT1C_HUMAN | GO:0006631 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024 |
Cross-references
| Database | ID | Description |
|---|---|---|
| Reactome | R-HSA-2046105 | |
| Wikipedia | Linoleic_acid |
Cross-Ontology Relations
| Relation | Other Ontology | ID | Term |
|---|---|---|---|
| has_primary_input_or_output | CHEBI | CHEBI:30245 | linoleate |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0043651 based on ALL annotations
The top 100 of 360 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
linoleic acid metabolic process
|
105,908.53 | 100.00 | 1,871 | 1,871 |
|
linoleate 11-lipoxygenase activity
|
105,908.54 | 48.74 | 912 | 912 |
|
lipoxygenase pathway
|
52,654.24 | 15.77 | 351 | 706 |
|
lauric acid metabolic process
|
98,373.54 | 12.44 | 235 | 253 |
|
icosanoid biosynthetic process
|
74,042.24 | 12.01 | 237 | 339 |
|
arachidonate monooxygenase activity
|
52,954.27 | 11.28 | 238 | 476 |
|
arachidonate 15-lipoxygenase activity
|
81,913.63 | 10.26 | 198 | 256 |
|
arachidonate 12(S)-lipoxygenase activity
|
74,061.91 | 10.22 | 200 | 286 |
|
linoleate 13S-lipoxygenase activity
|
60,782.29 | 9.81 | 198 | 345 |
|
hepoxilin biosynthetic process
|
88,423.63 | 9.29 | 177 | 212 |
| Totals | 14929 | 1436734 | ||
No co-occurrence statistics for GO:0043651 based on MANUAL annotations
The top 100 of 310 co-occurring terms
| Co-occurring Term | PR | S% | #Together | #Compared |
|---|---|---|---|---|
|
linoleic acid metabolic process
|
14,551.89 | 100.00 | 97 | 97 |
|
hepoxilin biosynthetic process
|
10,485.92 | 42.24 | 49 | 68 |
|
lipoxygenase pathway
|
3,816.89 | 20.69 | 48 | 183 |
|
arachidonate 12(S)-lipoxygenase activity
|
6,085.33 | 17.83 | 23 | 55 |
|
arachidonate 15-lipoxygenase activity
|
6,277.28 | 17.46 | 22 | 51 |
|
arachidonate metabolic process
|
2,144.49 | 13.94 | 70 | 475 |
|
obsolete hepoxilin A3 synthase activity
|
14,551.89 | 13.40 | 13 | 13 |
|
icosanoid biosynthetic process
|
7,275.94 | 12.61 | 14 | 28 |
|
lipoxin A4 biosynthetic process
|
14,551.89 | 12.37 | 12 | 12 |
|
alpha-linolenic acid metabolic process
|
9,190.67 | 11.54 | 12 | 19 |
| Totals | 758 | 9001 | ||
Change Log
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- Definition / Synonyms
- Definition / Synonyms
- Relationships
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- Cross-references
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- Other
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| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2024-12-05 | Added | XREF | Reactome:R-HSA-2046105 |
| 2020-09-07 | Added | RELATION | is a GO:0120254 (olefinic compound metabolic process) |
| 2009-07-03 | Added | RELATION | is a GO:0033559 (unsaturated fatty acid metabolic process) |
| 2009-07-03 | Deleted | RELATION | is a GO:0006631 (fatty acid metabolic process) |
| 2009-07-03 | Added | RELATION | is a GO:0001676 (long-chain fatty acid metabolic process) |
| 2009-03-29 | Added | XREF | Wikipedia:Linoleic_acid |
| 2008-05-13 | Added | DEFINITION | The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2. |
| 2008-05-12 | Deleted | DEFINITION | The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2. |
| 2008-04-01 | Updated | RELATION | is a GO:0006631 (fatty acid metabolic process) |
| 2007-08-09 | Deleted | SYNONYM | linoleic acid metabolism |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2007-01-15 | Updated | TERM | linoleic acid metabolic process |
| 2006-05-28 | Added | TERM | linoleic acid metabolism |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2008-05-13 | Added | DEFINITION | The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2. |
| 2008-05-12 | Deleted | DEFINITION | The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2. |
| 2007-08-09 | Deleted | SYNONYM | linoleic acid metabolism |
| 2007-08-09 | Added | SYNONYM | linoleic acid metabolism |
| 2007-01-29 | Added | SYNONYM | linoleic acid metabolism |
| 2006-05-28 | Added | DEFINITION | The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2. |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2020-09-07 | Added | RELATION | is a GO:0120254 (olefinic compound metabolic process) |
| 2009-07-03 | Added | RELATION | is a GO:0033559 (unsaturated fatty acid metabolic process) |
| 2009-07-03 | Deleted | RELATION | is a GO:0006631 (fatty acid metabolic process) |
| 2009-07-03 | Added | RELATION | is a GO:0001676 (long-chain fatty acid metabolic process) |
| 2008-04-01 | Updated | RELATION | is a GO:0006631 (fatty acid metabolic process) |
| Timestamp | Action | Category | Detail |
|---|---|---|---|
| 2024-12-05 | Added | XREF | Reactome:R-HSA-2046105 |
| 2009-03-29 | Added | XREF | Wikipedia:Linoleic_acid |
| Timestamp | Action | Category | Detail |
|---|
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