This term is obsolete.

GO:0044325 JSON

transmembrane transporter binding

Molecular Function

Definition (GO:0044325 GONUTS page)

Binding to a transmembrane transporter, a protein or protein complex that enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other. PMID:33199372

Acknowledgement

This term was created by the GO Consortium with support from: BHF image

51,569 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
ion channel binding narrow

Ancestor Chart

Ancestor chart for GO:0044325
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P21333-1 9606 FLNA_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684
NOT-qualified manual protein P63026 9913 VAMP2_BOVIN GO:0005515 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699
NOT-qualified manual protein Q86V48 9606 LUZP1_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684

Cross-references

Database ID Description
InterPro IPR037658 Voltage-dependent calcium channel beta subunit-associated regulatory protein

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0042980 obsolete cystic fibrosis transmembrane conductance regulator binding replaced_by GO:0044325

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0044325 based on ALL annotations
The top 100 of 3,285 co-occurring terms
Co-occurring Term PR S% #Together #Compared
transmembrane transporter binding
3,814.55 100.00 51,104 51,104
positive regulation of synaptic transmission
2,526.57 21.57 12,382 18,694
cytoskeleton of presynaptic active zone
2,211.37 20.60 12,377 21,350
regulation of synaptic plasticity
1,975.05 19.77 12,385 23,920
calcium ion-regulated exocytosis of neurotransmitter
1,884.75 19.42 12,385 25,066
regulation of synaptic vesicle exocytosis
2,590.41 18.49 10,352 15,244
regulation of membrane potential
1,181.55 17.02 14,017 45,253
potassium channel regulator activity
1,392.12 15.14 10,504 28,782
presynaptic membrane
917.87 13.97 12,774 53,087
regulation of potassium ion transmembrane transport
1,709.42 12.54 7,577 16,908
Totals 368301 5719625
No co-occurrence statistics for GO:0044325 based on MANUAL annotations
The top 100 of 3,040 co-occurring terms
Co-occurring Term PR S% #Together #Compared
transmembrane transporter binding
1,097.54 100.00 1,177 1,177
potassium channel regulator activity
436.98 14.31 215 540
voltage-gated potassium channel complex
245.65 14.15 327 1,461
potassium channel activator activity
1,050.83 11.41 135 141
regulation of heart rate by cardiac conduction
585.66 9.86 127 238
regulation of potassium ion transmembrane transport
483.09 8.62 114 259
regulation of ventricular cardiac muscle cell membrane repolarization
659.79 8.35 104 173
ventricular cardiac muscle cell action potential
1,005.22 8.26 98 107
voltage-gated potassium channel activity
190.82 8.04 153 880
protein localization to plasma membrane
105.33 6.28 181 1,886
Totals 6080 56265

GO Slims

This term is present in the following GO Consortium-maintained GO slims:

GO slim name Total Number of Terms in Slim
goslim_chembl 296

Change Log

Timestamp Action Category Detail
2021-05-15 Updated TERM transmembrane transporter binding
2021-05-15 Added DEFINITION Binding to a transmembrane transporter, a protein or protein complex that enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
2021-05-15 Deleted DEFINITION Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
2021-05-15 Added SYNONYM ion channel binding
2021-02-17 Added RELATION has part GO:0008200 (ion channel inhibitor activity)
2015-05-19 Deleted SUBSET goslim_ChEMBL
2015-05-19 Added SUBSET goslim_chembl
2015-05-11 Added SUBSET goslim_ChEMBL
2010-08-06 Added RELATION is a GO:0005515 (protein binding)
2010-08-06 Added TERM ion channel binding
Timestamp Action Category Detail
2021-05-15 Updated TERM transmembrane transporter binding
2010-08-06 Added TERM ion channel binding
Timestamp Action Category Detail
2021-05-15 Added DEFINITION Binding to a transmembrane transporter, a protein or protein complex that enables the transfer of a substance, usually a specific substance or a group of related substances, from one side of a membrane to the other.
2021-05-15 Deleted DEFINITION Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
2021-05-15 Added SYNONYM ion channel binding
2010-08-06 Added DEFINITION Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
Timestamp Action Category Detail
2021-02-17 Added RELATION has part GO:0008200 (ion channel inhibitor activity)
2010-08-06 Added RELATION is a GO:0005515 (protein binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
2015-05-19 Deleted SUBSET goslim_ChEMBL
2015-05-19 Added SUBSET goslim_chembl
2015-05-11 Added SUBSET goslim_ChEMBL
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