This term is obsolete.
Although in some literature 'microspike' and 'filopodium' are used synonymously, in GO microspike refers to a cell projection that is distinct from a filopodium. See also 'filopodium ; GO:0030175'.

GO:0044393 JSON

microspike

Cellular Component

Definition (GO:0044393 GONUTS page)

A dynamic, actin-rich projection extending from the surface of a migrating animal cell. PMID:11429692 PMID:12153987 PMID:19095735

Comments

Although in some literature 'microspike' and 'filopodium' are used synonymously, in GO microspike refers to a cell projection that is distinct from a filopodium. See also 'filopodium ; GO:0030175'.

179 annotations

Ancestor Chart

Ancestor chart for GO:0044393
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Ancestor chart

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0044393 microspike Never in Taxon 4751 Fungi
GO:0044393 microspike Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Replaces

This term can be used instead of these obsolete terms:

GO Identifier GO Term Name Reason
GO:0036043 obsolete microspike replaced_by GO:0044393

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0044393 based on ALL annotations
The top 100 of 141 co-occurring terms
Co-occurring Term PR S% #Together #Compared
microspike
1,145,403.80 100.00 173 173
microspike assembly
313,709.34 21.45 86 314
establishment of apical/basal cell polarity
254,534.17 18.14 86 387
parallel actin filament bundle assembly
216,970.78 15.90 86 454
positive regulation of extracellular matrix disassembly
215,546.47 15.81 86 457
positive regulation of podosome assembly
122,062.87 9.62 86 807
cell projection membrane
50,906.84 4.25 86 1,935
positive regulation of lamellipodium assembly
38,091.54 3.22 86 2,586
regulation of microvillus assembly
31,785.97 2.70 86 3,099
positive regulation of filopodium assembly
11,669.79 1.01 86 8,441
Totals 3093 4730976
No co-occurrence statistics for GO:0044393 based on MANUAL annotations
The top 100 of 134 co-occurring terms
Co-occurring Term PR S% #Together #Compared
microspike
141,153.30 100.00 10 10
microspike assembly
26,466.25 13.04 3 16
negative regulation of pinocytosis
23,525.55 10.00 2 12
Schwann cell microvillus
47,051.10 8.33 1 3
establishment of apical/basal cell polarity
13,660.00 7.89 3 31
positive regulation of cell projection organization
15,683.70 7.69 2 18
positive regulation of podosome assembly
12,832.12 7.50 3 33
negative regulation of caveolin-mediated endocytosis
11,292.27 6.06 2 25
positive regulation of extracellular matrix disassembly
9,624.09 5.88 3 44
parallel actin filament bundle assembly
10,082.38 5.56 2 28
Totals 189 64230

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2022-06-20 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2017-03-23 Deleted RELATION is a GO:0042995 (cell projection)
2017-03-23 Added RELATION is a GO:0120025 (plasma membrane bounded cell projection)
2011-12-18 Added TERM microspike
2011-12-18 Added RELATION is a GO:0042995 (cell projection)
2011-12-18 Added DEFINITION A dynamic, actin-rich projection extending from the surface of a migrating animal cell.
Timestamp Action Category Detail
2011-12-18 Added TERM microspike
Timestamp Action Category Detail
2011-12-18 Added DEFINITION A dynamic, actin-rich projection extending from the surface of a migrating animal cell.
Timestamp Action Category Detail
2017-03-23 Deleted RELATION is a GO:0042995 (cell projection)
2017-03-23 Added RELATION is a GO:0120025 (plasma membrane bounded cell projection)
2011-12-18 Added RELATION is a GO:0042995 (cell projection)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2022-06-20 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
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