Although in some literature 'microspike' and 'filopodium' are used synonymously, in GO microspike refers to a cell projection that is distinct from a filopodium. See also 'filopodium ; GO:0030175'.
GO:0044393
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microspike
Cellular Component
Definition (GO:0044393 GONUTS page)
A dynamic, actin-rich projection extending from the surface of a migrating animal cell. PMID:11429692 PMID:12153987 PMID:19095735
Comments
Although in some literature 'microspike' and 'filopodium' are used synonymously, in GO microspike refers to a cell projection that is distinct from a filopodium. See also 'filopodium ; GO:0030175'.
Ancestor Chart
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0044393 | microspike | Never in Taxon | 4751 | Fungi | |
GO:0044393 | microspike | Only in Taxon | 131567 | cellular organisms |
More information on taxon constraints in GO is available here
Replaces
This term can be used instead of these obsolete terms:
GO Identifier | GO Term Name | Reason |
---|---|---|
GO:0036043 | obsolete microspike | replaced_by GO:0044393 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0044393 based on ALL annotations
The top 100 of 141 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
microspike
|
1,145,403.80 | 100.00 | 173 | 173 |
microspike assembly
|
313,709.34 | 21.45 | 86 | 314 |
establishment of apical/basal cell polarity
|
254,534.17 | 18.14 | 86 | 387 |
parallel actin filament bundle assembly
|
216,970.78 | 15.90 | 86 | 454 |
positive regulation of extracellular matrix disassembly
|
215,546.47 | 15.81 | 86 | 457 |
positive regulation of podosome assembly
|
122,062.87 | 9.62 | 86 | 807 |
cell projection membrane
|
50,906.84 | 4.25 | 86 | 1,935 |
positive regulation of lamellipodium assembly
|
38,091.54 | 3.22 | 86 | 2,586 |
regulation of microvillus assembly
|
31,785.97 | 2.70 | 86 | 3,099 |
positive regulation of filopodium assembly
|
11,669.79 | 1.01 | 86 | 8,441 |
Totals | 3093 | 4730976 |
No co-occurrence statistics for GO:0044393 based on MANUAL annotations
The top 100 of 134 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
microspike
|
141,153.30 | 100.00 | 10 | 10 |
microspike assembly
|
26,466.25 | 13.04 | 3 | 16 |
negative regulation of pinocytosis
|
23,525.55 | 10.00 | 2 | 12 |
Schwann cell microvillus
|
47,051.10 | 8.33 | 1 | 3 |
establishment of apical/basal cell polarity
|
13,660.00 | 7.89 | 3 | 31 |
positive regulation of cell projection organization
|
15,683.70 | 7.69 | 2 | 18 |
positive regulation of podosome assembly
|
12,832.12 | 7.50 | 3 | 33 |
negative regulation of caveolin-mediated endocytosis
|
11,292.27 | 6.06 | 2 | 25 |
positive regulation of extracellular matrix disassembly
|
9,624.09 | 5.88 | 3 | 44 |
parallel actin filament bundle assembly
|
10,082.38 | 5.56 | 2 | 28 |
Totals | 189 | 64230 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2022-06-20 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2017-03-23 | Deleted | RELATION | is a GO:0042995 (cell projection) |
2017-03-23 | Added | RELATION | is a GO:0120025 (plasma membrane bounded cell projection) |
2011-12-18 | Added | TERM | microspike |
2011-12-18 | Added | RELATION | is a GO:0042995 (cell projection) |
2011-12-18 | Added | DEFINITION | A dynamic, actin-rich projection extending from the surface of a migrating animal cell. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-12-18 | Added | TERM | microspike |
Timestamp | Action | Category | Detail |
---|---|---|---|
2011-12-18 | Added | DEFINITION | A dynamic, actin-rich projection extending from the surface of a migrating animal cell. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2017-03-23 | Deleted | RELATION | is a GO:0042995 (cell projection) |
2017-03-23 | Added | RELATION | is a GO:0120025 (plasma membrane bounded cell projection) |
2011-12-18 | Added | RELATION | is a GO:0042995 (cell projection) |
Timestamp | Action | Category | Detail |
---|
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2022-06-20 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
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