This term is obsolete.

GO:0044754 JSON

autolysosome

Cellular Component

Definition (GO:0044754 GONUTS page)

A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome or amphisome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases. PMID:19008921 PMID:24657946

2,188 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
degrading autophagic vacuole exact
AVd exact

Ancestor Chart

Ancestor chart for GO:0044754
Chart options
Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0044754

Child Term Relationship to
GO:0044754
autolysosome membrane
part_of
autolysosome lumen
part_of

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0044754 autolysosome Never in Taxon 4751 Fungi
GO:0044754 autolysosome Only in Taxon 131567 cellular organisms

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A0A096MJ18 10116 A0A096MJ18_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A096MK97 10116 A0A096MK97_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0D1E8X3 5270 A0A0D1E8X3_MYCMD GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A0G2JZ79 10116 SIR1_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A0G2K320 10116 A0A0G2K320_RAT GO:0005764 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A1L8G9S0 8355 A0A1L8G9S0_XENLA GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1S4L3K3 6945 A0A1S4L3K3_IXOSC GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A1W2Q633 10116 A0A1W2Q633_RAT GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A0A2K5ATM2 6239 A0A2K5ATM2_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein A0A2K5ATM9 6239 A0A2K5ATM9_CAEEL GO:0005737 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-references

Database ID Description
NIF_Subcellular sao8444068431
UniProtKB-SubCell SL-0535 Autolysosome

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0044754 based on ALL annotations
The top 100 of 614 co-occurring terms
Co-occurring Term PR S% #Together #Compared
autolysosome
96,849.88 100.00 2,046 2,046
lysosomal lumen acidification
14,462.01 7.27 254 1,701
lysosomal protein catabolic process
17,420.54 5.97 168 934
negative regulation of ferroptosis
16,041.14 4.90 133 803
caveola neck
96,849.89 4.59 94 94
peroxidase inhibitor activity
95,830.41 4.59 94 95
Wnt signalosome assembly
88,387.27 4.57 94 103
GTP-dependent protein kinase activity
87,537.39 4.57 94 104
amphisome
7,495.89 4.52 201 2,597
regulation of neuron maturation
50,297.73 4.41 94 181
Totals 11372 121924
No co-occurrence statistics for GO:0044754 based on MANUAL annotations
The top 100 of 535 co-occurring terms
Co-occurring Term PR S% #Together #Compared
autolysosome
21,715.89 100.00 65 65
regulation of cellular response to osmotic stress
21,715.90 16.92 11 11
phagosome-lysosome docking
21,715.90 16.92 11 11
positive regulation of caveolin-mediated endocytosis
15,924.99 15.94 11 15
regulation of arginine biosynthetic process
15,924.99 15.94 11 15
renal potassium excretion
12,572.36 15.07 11 19
regulation of phagosome maturation
12,572.36 15.07 11 19
glycolipid transport
12,572.36 15.07 11 19
regulation of modification of synaptic structure
11,374.99 14.67 11 21
plasma membrane raft organization
10,857.95 14.47 11 22
Totals 768 6886

Change Log

Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
2024-01-30 Deleted RELATION is a GO:0005776 (autophagosome)
2024-01-30 Deleted DEFINITION A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.
2024-01-30 Added DEFINITION A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome or amphisome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.
2024-01-30 Deleted SYNONYM autophagolysosome
2013-10-17 Added XREF NIF_Subcellular:sao8444068431
2012-12-06 Added SYNONYM autophagolysosome
2012-12-06 Added SYNONYM AVd
2012-12-06 Added TERM autolysosome
Timestamp Action Category Detail
2012-12-06 Added TERM autolysosome
Timestamp Action Category Detail
2024-01-30 Deleted DEFINITION A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.
2024-01-30 Added DEFINITION A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome or amphisome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.
2024-01-30 Deleted SYNONYM autophagolysosome
2012-12-06 Added SYNONYM autophagolysosome
2012-12-06 Added SYNONYM AVd
2012-12-06 Added DEFINITION A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.
2012-12-06 Added SYNONYM degrading autophagic vacuole
Timestamp Action Category Detail
2024-01-30 Deleted RELATION is a GO:0005776 (autophagosome)
2012-12-06 Added RELATION is a GO:0005767 (secondary lysosome)
2012-12-06 Added RELATION is a GO:0005776 (autophagosome)
Timestamp Action Category Detail
2013-10-17 Added XREF NIF_Subcellular:sao8444068431
Timestamp Action Category Detail
2024-09-05 Added CONSTRAINT never_in_taxon NCBITaxon:4751 (Fungi)
2024-09-05 Added CONSTRAINT in_taxon NCBITaxon:131567 (cellular organisms)
Please Wait...

Not found :(

Sorry, but the Term you were trying to view does not exist.

Reported error:

It looks like this may have been caused by:

  • a mistyped URL
  • an out-of-date link
This website requires cookies, and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our Privacy Notice and Terms of Use.