GO:0044754
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autolysosome
Cellular Component
Definition (GO:0044754 GONUTS page)
A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome or amphisome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases. PMID:19008921 PMID:24657946
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
degrading autophagic vacuole | exact |
AVd | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0044754
Child Term | Relationship to GO:0044754 |
---|---|
autolysosome membrane
|
part_of |
autolysosome lumen
|
part_of |
Taxon Constraints
The use of this term should conform to the following taxon constraints:
Ancestor GO ID | Ancestor GO Term Name | Relationship | Taxon ID | Taxon | Reference(s) |
---|---|---|---|---|---|
GO:0044754 | autolysosome | Never in Taxon | 4751 | Fungi | |
GO:0044754 | autolysosome | Only in Taxon | 131567 | cellular organisms |
More information on taxon constraints in GO is available here
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A096MJ18 | 10116 | A0A096MJ18_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A096MK97 | 10116 | A0A096MK97_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0D1E8X3 | 5270 | A0A0D1E8X3_MYCMD | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A0G2JZ79 | 10116 | SIR1_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A0G2K320 | 10116 | A0A0G2K320_RAT | GO:0005764 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A1L8G9S0 | 8355 | A0A1L8G9S0_XENLA | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1S4L3K3 | 6945 | A0A1S4L3K3_IXOSC | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A1W2Q633 | 10116 | A0A1W2Q633_RAT | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 | |
NOT-qualified manual | protein | A0A2K5ATM2 | 6239 | A0A2K5ATM2_CAEEL | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | A0A2K5ATM9 | 6239 | A0A2K5ATM9_CAEEL | GO:0005737 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 |
Cross-references
Database | ID | Description |
---|---|---|
NIF_Subcellular | sao8444068431 | |
UniProtKB-SubCell | SL-0535 | Autolysosome |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0044754 based on ALL annotations
The top 100 of 614 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
autolysosome
|
96,849.88 | 100.00 | 2,046 | 2,046 |
lysosomal lumen acidification
|
14,462.01 | 7.27 | 254 | 1,701 |
lysosomal protein catabolic process
|
17,420.54 | 5.97 | 168 | 934 |
negative regulation of ferroptosis
|
16,041.14 | 4.90 | 133 | 803 |
caveola neck
|
96,849.89 | 4.59 | 94 | 94 |
peroxidase inhibitor activity
|
95,830.41 | 4.59 | 94 | 95 |
Wnt signalosome assembly
|
88,387.27 | 4.57 | 94 | 103 |
GTP-dependent protein kinase activity
|
87,537.39 | 4.57 | 94 | 104 |
amphisome
|
7,495.89 | 4.52 | 201 | 2,597 |
regulation of neuron maturation
|
50,297.73 | 4.41 | 94 | 181 |
Totals | 11372 | 121924 |
No co-occurrence statistics for GO:0044754 based on MANUAL annotations
The top 100 of 535 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
autolysosome
|
21,715.89 | 100.00 | 65 | 65 |
regulation of cellular response to osmotic stress
|
21,715.90 | 16.92 | 11 | 11 |
phagosome-lysosome docking
|
21,715.90 | 16.92 | 11 | 11 |
positive regulation of caveolin-mediated endocytosis
|
15,924.99 | 15.94 | 11 | 15 |
regulation of arginine biosynthetic process
|
15,924.99 | 15.94 | 11 | 15 |
renal potassium excretion
|
12,572.36 | 15.07 | 11 | 19 |
regulation of phagosome maturation
|
12,572.36 | 15.07 | 11 | 19 |
glycolipid transport
|
12,572.36 | 15.07 | 11 | 19 |
regulation of modification of synaptic structure
|
11,374.99 | 14.67 | 11 | 21 |
plasma membrane raft organization
|
10,857.95 | 14.47 | 11 | 22 |
Totals | 768 | 6886 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
2024-01-30 | Deleted | RELATION | is a GO:0005776 (autophagosome) |
2024-01-30 | Deleted | DEFINITION | A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases. |
2024-01-30 | Added | DEFINITION | A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome or amphisome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases. |
2024-01-30 | Deleted | SYNONYM | autophagolysosome |
2013-10-17 | Added | XREF | NIF_Subcellular:sao8444068431 |
2012-12-06 | Added | SYNONYM | autophagolysosome |
2012-12-06 | Added | SYNONYM | AVd |
2012-12-06 | Added | TERM | autolysosome |
Timestamp | Action | Category | Detail |
---|---|---|---|
2012-12-06 | Added | TERM | autolysosome |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-01-30 | Deleted | DEFINITION | A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases. |
2024-01-30 | Added | DEFINITION | A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome or amphisome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases. |
2024-01-30 | Deleted | SYNONYM | autophagolysosome |
2012-12-06 | Added | SYNONYM | autophagolysosome |
2012-12-06 | Added | SYNONYM | AVd |
2012-12-06 | Added | DEFINITION | A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases. |
2012-12-06 | Added | SYNONYM | degrading autophagic vacuole |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-01-30 | Deleted | RELATION | is a GO:0005776 (autophagosome) |
2012-12-06 | Added | RELATION | is a GO:0005767 (secondary lysosome) |
2012-12-06 | Added | RELATION | is a GO:0005776 (autophagosome) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2013-10-17 | Added | XREF | NIF_Subcellular:sao8444068431 |
Timestamp | Action | Category | Detail |
---|---|---|---|
2024-09-05 | Added | CONSTRAINT | never_in_taxon NCBITaxon:4751 (Fungi) |
2024-09-05 | Added | CONSTRAINT | in_taxon NCBITaxon:131567 (cellular organisms) |
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