This term is obsolete.

GO:0045004 JSON

DNA replication proofreading

Biological Process

Definition (GO:0045004 GONUTS page)

Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.

65,881 annotations

Ancestor Chart

Ancestor chart for GO:0045004
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Guidance for interpreting DNA repair investigations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A6K9T7 10116 A6K9T7_RAT GO:0006974 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K9T7 10116 A6K9T7_RAT GO:0006281 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A8VU90 10090 ANKL1_MOUSE GO:0006974 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27010503
NOT-qualified manual protein A8VU90 10090 ANKL1_MOUSE GO:0006281 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27010503
NOT-qualified manual protein D3ZVK1 10116 MCM8_RAT GO:0006260 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D4A332 10116 D4A332_RAT GO:0006974 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D4A332 10116 D4A332_RAT GO:0006281 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein F1M5F3 10116 MCM9_RAT GO:0006260 3 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein F1N2W9 9913 MCM9_BOVIN GO:0006260 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein L0T864 83332 FPG2_MYCTU GO:0006281 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:20031487

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0045004 based on ALL annotations
The top 100 of 371 co-occurring terms
Co-occurring Term PR S% #Together #Compared
DNA replication proofreading
2,960.26 100.00 65,852 65,852
base-excision repair, gap-filling
2,907.19 22.29 14,736 15,005
nucleotide-excision repair, DNA gap filling
1,765.30 19.32 14,640 24,550
3'-5'-DNA exonuclease activity
1,589.24 18.10 14,128 26,316
3'-5' exonuclease activity
378.94 12.13 46,060 359,819
DNA-directed DNA polymerase activity
243.49 7.99 48,567 590,457
DNA metabolic process
238.70 7.80 46,507 576,758
single-stranded DNA 3'-5' DNA exonuclease activity
869.41 7.62 6,147 20,930
epsilon DNA polymerase complex
1,113.39 7.62 5,741 15,264
DNA polymerase activity
296.50 7.56 15,533 155,084
Totals 689169 109615028
No co-occurrence statistics for GO:0045004 based on MANUAL annotations
The top 100 of 115 co-occurring terms
Co-occurring Term PR S% #Together #Compared
DNA replication proofreading
4,784.44 100.00 270 270
base-excision repair, gap-filling
4,410.01 73.61 212 230
nucleotide-excision repair, DNA gap filling
2,481.26 45.04 209 403
3'-5'-DNA exonuclease activity
1,590.70 24.39 129 388
single-stranded DNA 3'-5' DNA exonuclease activity
2,069.55 23.72 93 215
delta DNA polymerase complex
1,366.98 21.22 122 427
epsilon DNA polymerase complex
1,343.27 17.87 89 317
leading strand elongation
900.84 13.68 90 478
DNA-directed DNA polymerase activity
665.69 13.48 219 1,574
DNA-templated DNA replication
378.08 7.33 136 1,721
Totals 2031 181900

Change Log

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.
2008-05-12 Deleted DEFINITION Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.
2008-04-01 Updated RELATION is a GO:0045005 (DNA-templated DNA replication maintenance of fidelity)
2008-04-01 Updated RELATION is a GO:0006281 (DNA repair)
2002-11-27 Added DEFINITION Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.
2002-03-15 Added TERM DNA replication proofreading
Timestamp Action Category Detail
2002-03-15 Added TERM DNA replication proofreading
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.
2008-05-12 Deleted DEFINITION Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.
2002-11-27 Added DEFINITION Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0045005 (DNA-templated DNA replication maintenance of fidelity)
2008-04-01 Updated RELATION is a GO:0006281 (DNA repair)
Timestamp Action Category Detail
Timestamp Action Category Detail
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