This term is obsolete.

GO:0045004 JSON

DNA replication proofreading

Biological Process

Definition (GO:0045004 GONUTS page)

Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.

66,988 annotations

Ancestor Chart

Ancestor chart for GO:0045004
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Guidance for interpreting DNA repair investigations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A6K9T7 10116 A6K9T7_RAT GO:0006974 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A6K9T7 10116 A6K9T7_RAT GO:0006281 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein A8VU90 10090 ANKL1_MOUSE GO:0006974 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27010503
NOT-qualified manual protein A8VU90 10090 ANKL1_MOUSE GO:0006281 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:27010503
NOT-qualified manual protein D3ZVK1 10116 MCM8_RAT GO:0006260 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D4A332 10116 D4A332_RAT GO:0006281 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein D4A332 10116 D4A332_RAT GO:0006974 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096
NOT-qualified manual protein F1M5F3 10116 MCM9_RAT GO:0006260 3 NOT-qualified manual annotations exist with these evidence codes: ECO:0000250, ECO:0000266 from these references: GO_REF:0000024, GO_REF:0000096
NOT-qualified manual protein F1N2W9 9913 MCM9_BOVIN GO:0006260 1 NOT-qualified manual annotation exists with evidence code ECO:0000250 from this reference: GO_REF:0000024
NOT-qualified manual protein L0T864 83332 FPG2_MYCTU GO:0006281 1 NOT-qualified manual annotation exists with evidence code ECO:0000314 from this reference: PMID:20031487

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0045004 based on ALL annotations
The top 100 of 369 co-occurring terms
Co-occurring Term PR S% #Together #Compared
DNA replication proofreading
2,959.57 100.00 66,954 66,954
base-excision repair, gap-filling
2,908.31 22.54 15,149 15,416
nucleotide-excision repair, DNA gap filling
1,765.61 19.52 15,054 25,234
3'-5'-DNA exonuclease activity
1,576.81 18.15 14,456 27,133
3'-5' exonuclease activity
376.14 12.04 46,626 366,862
single-stranded DNA 3'-5' DNA exonuclease activity
878.49 7.75 6,356 21,413
epsilon DNA polymerase complex
1,115.23 7.75 5,950 15,790
DNA-directed DNA polymerase activity
230.71 7.58 49,349 633,065
DNA polymerase activity
290.00 7.38 15,383 156,992
delta DNA polymerase complex
984.07 7.33 5,752 17,299
Totals 678953 111781707
No co-occurrence statistics for GO:0045004 based on MANUAL annotations
The top 100 of 114 co-occurring terms
Co-occurring Term PR S% #Together #Compared
DNA replication proofreading
4,987.75 100.00 283 283
base-excision repair, gap-filling
4,621.30 75.42 227 245
nucleotide-excision repair, DNA gap filling
2,580.27 45.53 224 433
single-stranded DNA 3'-5' DNA exonuclease activity
2,469.89 26.55 103 208
3'-5'-DNA exonuclease activity
1,638.31 24.15 135 411
delta DNA polymerase complex
1,380.05 20.65 127 459
epsilon DNA polymerase complex
1,423.02 18.64 99 347
leading strand elongation
944.65 14.06 100 528
DNA-directed DNA polymerase activity
671.70 13.11 235 1,745
DNA-templated DNA replication
377.29 7.03 141 1,864
Totals 2165 237048

Change Log

Timestamp Action Category Detail
2008-05-13 Added DEFINITION Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.
2008-05-12 Deleted DEFINITION Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.
2008-04-01 Updated RELATION is a GO:0045005 (DNA-templated DNA replication maintenance of fidelity)
2008-04-01 Updated RELATION is a GO:0006281 (DNA repair)
2002-11-27 Added DEFINITION Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.
2002-03-15 Added TERM DNA replication proofreading
Timestamp Action Category Detail
2002-03-15 Added TERM DNA replication proofreading
Timestamp Action Category Detail
2008-05-13 Added DEFINITION Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.
2008-05-12 Deleted DEFINITION Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.
2002-11-27 Added DEFINITION Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0045005 (DNA-templated DNA replication maintenance of fidelity)
2008-04-01 Updated RELATION is a GO:0006281 (DNA repair)
Timestamp Action Category Detail
Timestamp Action Category Detail
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