GO:0045236
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CXCR chemokine receptor binding
Molecular Function
Definition (GO:0045236 GONUTS page)
Binding to a chemokine receptor in the CXCR family. PMID:11910892
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
alpha chemokine receptor ligand | narrow |
alpha chemokine receptor binding | exact |
C-X-C chemokine receptor ligand | narrow |
CXC chemokine receptor ligand | narrow |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0045236
Child Term | Relationship to GO:0045236 |
---|---|
CXCR6 chemokine receptor binding
|
is_a |
CXCR5 chemokine receptor binding
|
is_a |
CXCR4 chemokine receptor binding
|
is_a |
interleukin-8 receptor binding
|
is_a |
CXCR3 chemokine receptor binding
|
is_a |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A8XY28 | 6238 | A8XY28_CAEBR | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PL19 | 6945 | B7PL19_IXOSC | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | B7PVH4 | 6945 | B7PVH4_IXOSC | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | O16262 | 6239 | NIPI4_CAEEL | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033 | |
NOT-qualified manual | protein | O95970 | 9606 | LGI1_HUMAN | GO:0005102 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20463223 | |
NOT-qualified manual | protein | P21333-1 | 9606 | FLNA_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 | |
NOT-qualified manual | protein | P63026 | 9913 | VAMP2_BOVIN | GO:0005515 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699 | |
NOT-qualified manual | protein | Q86V48 | 9606 | LUZP1_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 | |
NOT-qualified manual | protein | Q8K4Y5 | 10116 | LGI1_RAT | GO:0005102 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0045236 based on ALL annotations
The top 100 of 274 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
CXCR chemokine receptor binding
|
585,401.75 | 100.00 | 333 | 333 |
regulation of protein deubiquitination
|
579,107.10 | 27.54 | 92 | 93 |
positive regulation of receptor catabolic process
|
199,994.90 | 18.53 | 96 | 281 |
T cell anergy
|
170,433.42 | 16.52 | 92 | 316 |
positive regulation of T cell anergy
|
166,225.20 | 16.28 | 92 | 324 |
negative regulation of cytoplasmic pattern recognition receptor signaling pathway
|
150,263.55 | 15.71 | 96 | 374 |
chemokine (C-X-C motif) ligand 12 signaling pathway
|
171,750.11 | 14.09 | 71 | 242 |
negative regulation of leukocyte tethering or rolling
|
164,934.62 | 13.81 | 71 | 252 |
positive regulation of vasculature development
|
120,125.80 | 11.68 | 71 | 346 |
CXCL12-activated CXCR4 signaling pathway
|
92,983.27 | 10.01 | 71 | 447 |
Totals | 4670 | 382624 |
No co-occurrence statistics for GO:0045236 based on MANUAL annotations
The top 100 of 265 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
CXCR chemokine receptor binding
|
7,059.01 | 100.00 | 183 | 183 |
chemokine-mediated signaling pathway
|
2,010.33 | 28.16 | 176 | 618 |
chemokine activity
|
1,938.20 | 27.16 | 176 | 641 |
neutrophil chemotaxis
|
1,958.78 | 26.63 | 159 | 573 |
antimicrobial humoral immune response mediated by antimicrobial peptide
|
1,240.20 | 17.12 | 159 | 905 |
cellular response to lipopolysaccharide
|
845.80 | 11.77 | 159 | 1,327 |
CXCR3 chemokine receptor binding
|
5,111.70 | 10.99 | 21 | 29 |
inflammatory response
|
498.87 | 7.00 | 160 | 2,264 |
induction of positive chemotaxis
|
976.72 | 6.88 | 22 | 159 |
chemokine receptor binding
|
1,384.12 | 4.46 | 10 | 51 |
Totals | 1762 | 23365 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with a chemokine receptor in the CXCR family. |
2021-05-24 | Added | DEFINITION | Binding to a chemokine receptor in the CXCR family. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with a chemokine receptor in the CXCR family. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with a chemokine receptor in the CXCR family. |
2008-05-13 | Added | DEFINITION | Interacting selectively with a chemokine receptor in the CXCR family. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with a chemokine receptor in the CXCR family. |
2008-04-01 | Updated | RELATION | is a GO:0042379 (chemokine receptor binding) |
2007-08-09 | Added | SYNONYM | alpha chemokine receptor ligand |
2007-08-09 | Added | SYNONYM | alpha chemokine receptor binding |
2007-08-09 | Added | SYNONYM | CXC chemokine receptor ligand |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-06-10 | Updated | TERM | CXCR chemokine receptor binding |
2003-03-19 | Updated | TERM | CXCR chemokine receptor binding activity |
2002-07-23 | Updated | TERM | CXCR chemokine receptor binding |
2002-07-15 | Updated | TERM | C-X-C chemokine receptor ligand |
2002-05-10 | Added | TERM | C-X-C chemokine receptor binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with a chemokine receptor in the CXCR family. |
2021-05-24 | Added | DEFINITION | Binding to a chemokine receptor in the CXCR family. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with a chemokine receptor in the CXCR family. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with a chemokine receptor in the CXCR family. |
2008-05-13 | Added | DEFINITION | Interacting selectively with a chemokine receptor in the CXCR family. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with a chemokine receptor in the CXCR family. |
2007-08-09 | Added | SYNONYM | alpha chemokine receptor ligand |
2007-08-09 | Added | SYNONYM | alpha chemokine receptor binding |
2007-08-09 | Added | SYNONYM | CXC chemokine receptor ligand |
2007-08-09 | Added | SYNONYM | C-X-C chemokine receptor ligand |
2007-08-09 | Deleted | SYNONYM | alpha chemokine receptor ligand |
2007-08-09 | Deleted | SYNONYM | CXC chemokine receptor ligand |
2007-08-09 | Deleted | SYNONYM | alpha chemokine receptor binding |
2007-08-09 | Deleted | SYNONYM | C-X-C chemokine receptor ligand |
2004-04-19 | Added | SYNONYM | alpha chemokine receptor binding |
2004-04-16 | Deleted | SYNONYM | alpha chemokine receptor binding |
2003-03-26 | Updated | DEFINITION | Interacting selectively with a chemokine receptor in the CXCR family. |
2002-11-27 | Added | DEFINITION | Interacting selectively and stoichiometrically with a chemokine receptor in the CXCR family. |
2002-07-23 | Added | SYNONYM | C-X-C chemokine receptor ligand |
2002-07-23 | Added | SYNONYM | alpha chemokine receptor ligand |
2002-07-23 | Added | SYNONYM | alpha chemokine receptor binding |
2002-07-23 | Added | SYNONYM | CXC chemokine receptor ligand |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0042379 (chemokine receptor binding) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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