This term is obsolete.

GO:0045236 JSON

CXCR chemokine receptor binding

Molecular Function

Definition (GO:0045236 GONUTS page)

Binding to a chemokine receptor in the CXCR family. PMID:11910892

986 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
alpha chemokine receptor ligand narrow
CXC chemokine receptor ligand narrow
C-X-C chemokine receptor ligand narrow
alpha chemokine receptor binding exact

Ancestor Chart

Ancestor chart for GO:0045236
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0045236

Child Term Relationship to
GO:0045236
CXCR6 chemokine receptor binding
is_a
CXCR4 chemokine receptor binding
is_a
CXCR5 chemokine receptor binding
is_a
CXCR3 chemokine receptor binding
is_a
interleukin-8 receptor binding
is_a

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A8XY28 6238 A8XY28_CAEBR GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PL19 6945 B7PL19_IXOSC GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PVH4 6945 B7PVH4_IXOSC GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O16262 6239 NIPI4_CAEEL GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O95970 9606 LGI1_HUMAN GO:0005102 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20463223
NOT-qualified manual protein P21333-1 9606 FLNA_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684
NOT-qualified manual protein P63026 9913 VAMP2_BOVIN GO:0005515 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699
NOT-qualified manual protein Q86V48 9606 LUZP1_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684
NOT-qualified manual protein Q8K4Y5 10116 LGI1_RAT GO:0005102 1 NOT-qualified manual annotation exists with evidence code ECO:0000266 from this reference: GO_REF:0000096

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0045236 based on ALL annotations
The top 100 of 265 co-occurring terms
Co-occurring Term PR S% #Together #Compared
CXCR chemokine receptor binding
629,063.06 100.00 315 315
regulation of protein deubiquitination
622,299.00 29.11 92 93
positive regulation of receptor catabolic process
213,432.12 19.00 95 280
T cell anergy
183,144.95 17.07 92 316
negative regulation of cytoplasmic pattern recognition receptor signaling pathway
159,788.75 15.99 95 374
negative regulation of leukocyte tethering or rolling
192,213.72 15.71 77 252
positive regulation of T cell anergy
142,546.31 14.63 92 406
chemokine (C-X-C motif) ligand 12 signaling pathway
184,559.83 14.61 71 242
positive regulation of vasculature development
129,085.20 12.03 71 346
CXCL12-activated CXCR4 signaling pathway
98,813.01 10.20 71 452
Totals 4413 389757
No co-occurrence statistics for GO:0045236 based on MANUAL annotations
The top 100 of 253 co-occurring terms
Co-occurring Term PR S% #Together #Compared
CXCR chemokine receptor binding
8,554.75 100.00 165 165
chemokine activity
2,775.46 31.98 158 487
neutrophil chemotaxis
2,183.87 24.66 145 568
antimicrobial humoral immune response mediated by antimicrobial peptide
1,343.50 14.75 117 745
cellular response to lipopolysaccharide
888.57 10.24 145 1,396
CXCR3 chemokine receptor binding
5,014.85 9.60 17 29
chemokine-mediated signaling pathway
1,031.60 8.84 41 340
inflammatory response
519.55 6.03 146 2,404
induction of positive chemotaxis
968.46 5.88 18 159
CCR3 chemokine receptor binding
2,654.92 4.86 9 29
Totals 1465 20734

Change Log

Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with a chemokine receptor in the CXCR family.
2021-05-24 Added DEFINITION Binding to a chemokine receptor in the CXCR family.
2009-07-03 Deleted DEFINITION Interacting selectively with a chemokine receptor in the CXCR family.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with a chemokine receptor in the CXCR family.
2008-05-13 Added DEFINITION Interacting selectively with a chemokine receptor in the CXCR family.
2008-05-12 Deleted DEFINITION Interacting selectively with a chemokine receptor in the CXCR family.
2008-04-01 Updated RELATION is a GO:0042379 (chemokine receptor binding)
2007-08-09 Added SYNONYM CXC chemokine receptor ligand
2007-08-09 Deleted SYNONYM alpha chemokine receptor binding
2007-08-09 Added SYNONYM C-X-C chemokine receptor ligand
Timestamp Action Category Detail
2003-06-10 Updated TERM CXCR chemokine receptor binding
2003-03-19 Updated TERM CXCR chemokine receptor binding activity
2002-07-23 Updated TERM CXCR chemokine receptor binding
2002-07-15 Updated TERM C-X-C chemokine receptor ligand
2002-05-10 Added TERM C-X-C chemokine receptor binding
Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with a chemokine receptor in the CXCR family.
2021-05-24 Added DEFINITION Binding to a chemokine receptor in the CXCR family.
2009-07-03 Deleted DEFINITION Interacting selectively with a chemokine receptor in the CXCR family.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with a chemokine receptor in the CXCR family.
2008-05-13 Added DEFINITION Interacting selectively with a chemokine receptor in the CXCR family.
2008-05-12 Deleted DEFINITION Interacting selectively with a chemokine receptor in the CXCR family.
2007-08-09 Added SYNONYM CXC chemokine receptor ligand
2007-08-09 Deleted SYNONYM alpha chemokine receptor binding
2007-08-09 Added SYNONYM C-X-C chemokine receptor ligand
2007-08-09 Deleted SYNONYM alpha chemokine receptor ligand
2007-08-09 Added SYNONYM alpha chemokine receptor binding
2007-08-09 Added SYNONYM alpha chemokine receptor ligand
2007-08-09 Deleted SYNONYM C-X-C chemokine receptor ligand
2007-08-09 Deleted SYNONYM CXC chemokine receptor ligand
2004-04-19 Added SYNONYM alpha chemokine receptor binding
2004-04-16 Deleted SYNONYM alpha chemokine receptor binding
2003-03-26 Updated DEFINITION Interacting selectively with a chemokine receptor in the CXCR family.
2002-11-27 Added DEFINITION Interacting selectively and stoichiometrically with a chemokine receptor in the CXCR family.
2002-07-23 Added SYNONYM alpha chemokine receptor binding
2002-07-23 Added SYNONYM CXC chemokine receptor ligand
2002-07-23 Added SYNONYM C-X-C chemokine receptor ligand
2002-07-23 Added SYNONYM alpha chemokine receptor ligand
Timestamp Action Category Detail
2008-04-01 Updated RELATION is a GO:0042379 (chemokine receptor binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
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