This term is obsolete.

GO:0045445 JSON

myoblast differentiation

Biological Process

Definition (GO:0045445 GONUTS page)

The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.

3,441 annotations

Synonyms

Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.

Synonym Type
myoblast cell differentiation exact

Ancestor Chart

Ancestor chart for GO:0045445
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Ancestor chart

Child Terms

This table lists all terms that are direct descendants (child terms) of GO:0045445

Child Term Relationship to
GO:0045445
cardiac muscle cell myoblast differentiation
is_a
myoblast differentiation involved in skeletal muscle regeneration
is_a
negative regulation of myoblast differentiation
negatively_regulates
myoblast fate commitment
part_of
positive regulation of myoblast differentiation
positively_regulates
myoblast development
part_of
regulation of myoblast differentiation
regulates

Taxon Constraints

The use of this term should conform to the following taxon constraints:

Ancestor GO ID Ancestor GO Term Name Relationship Taxon ID Taxon Reference(s)
GO:0045445 myoblast differentiation Only in Taxon 6072 Eumetazoa

More information on taxon constraints in GO is available here

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein A8XY28 6238 A8XY28_CAEBR GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PL19 6945 B7PL19_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein B7PVH4 6945 B7PVH4_IXOSC GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033
NOT-qualified manual protein O16262 6239 NIPI4_CAEEL GO:0030154 1 NOT-qualified manual annotation exists with evidence code ECO:0000318 from this reference: GO_REF:0000033

Cross-Ontology Relations

Relation Other Ontology ID Term
results_in_acquisition_of_features_of CL CL:0000056 myoblast

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0045445 based on ALL annotations
The top 100 of 1,399 co-occurring terms
Co-occurring Term PR S% #Together #Compared
myoblast differentiation
136,511.75 100.00 1,428 1,428
myotube differentiation involved in skeletal muscle regeneration
70,634.77 12.00 193 373
negative regulation of dopaminergic neuron differentiation
133,280.70 11.52 165 169
myotube cell development
66,133.93 11.49 187 386
positive regulation of muscle cell differentiation
50,252.91 11.02 194 527
myotube differentiation
29,894.02 10.31 233 1,064
positive regulation of skeletal muscle tissue development
36,301.69 8.84 167 628
myoblast proliferation
27,602.79 7.32 147 727
dorsal/ventral neural tube patterning
20,165.12 6.93 165 1,117
myoblast fate determination
133,808.55 6.92 99 101
Totals 11198 45973
No co-occurrence statistics for GO:0045445 based on MANUAL annotations
The top 100 of 1,222 co-occurring terms
Co-occurring Term PR S% #Together #Compared
myoblast differentiation
11,431.85 100.00 113 113
miRNA transcription
10,437.78 18.26 21 23
regulation of skeletal muscle cell differentiation
4,745.30 15.28 22 53
androgen receptor signaling pathway
2,228.24 11.06 23 118
estrogen receptor signaling pathway
1,964.85 10.05 22 128
positive regulation of DNA damage response, signal transduction by p53 class mediator
2,286.37 7.88 13 65
regulation of miRNA transcription
7,349.05 7.63 9 14
integrin alpha9-beta1 complex
6,430.42 7.50 9 16
regulation of collagen catabolic process
5,715.93 7.38 9 18
MH2 domain binding
4,899.36 7.20 9 21
Totals 892 10702

Change Log

Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:6072 (Eumetazoa)
2017-11-01 Deleted RELATION is a GO:0042692 (muscle cell differentiation)
2017-11-01 Added RELATION is a GO:0030154 (cell differentiation)
2017-11-01 Added RELATION part of GO:0061061 (muscle structure development)
2010-12-17 Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
2010-12-17 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
2010-03-11 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
2010-03-11 Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
2010-03-11 Deleted RELATION part of GO:0048741 (skeletal muscle fiber development)
2008-05-13 Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
Timestamp Action Category Detail
2005-02-21 Updated TERM myoblast differentiation
2005-01-13 Updated TERM myoblast cell differentiation
2002-08-01 Added TERM myoblast differentiation
Timestamp Action Category Detail
2010-12-17 Added DEFINITION The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
2010-12-17 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
2010-03-11 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
2010-03-11 Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
2008-05-13 Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
2008-05-12 Deleted DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
2007-11-27 Updated DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
2007-08-09 Deleted SYNONYM myoblast cell differentiation
2007-08-09 Added SYNONYM myoblast cell differentiation
2005-07-23 Updated DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a cell type that gives rise to mature contractile cells called myocytes. Fusion of myoblasts gives rise to the myotubes that eventually develop into skeletal muscle fibers.
2005-06-16 Updated DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
2005-02-21 Added SYNONYM myoblast cell differentiation
2005-01-21 Updated DEFINITION Processes whereby a relatively unspecialized cell acquires specialized features of a myoblast, a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
2002-11-27 Added DEFINITION The process whereby a relatively unspecialized cell acquires specialized features of a myoblast, a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
Timestamp Action Category Detail
2017-11-01 Deleted RELATION is a GO:0042692 (muscle cell differentiation)
2017-11-01 Added RELATION is a GO:0030154 (cell differentiation)
2017-11-01 Added RELATION part of GO:0061061 (muscle structure development)
2010-03-11 Deleted RELATION part of GO:0048741 (skeletal muscle fiber development)
2008-04-01 Updated RELATION is a GO:0042692 (muscle cell differentiation)
2008-04-01 Updated RELATION part of GO:0048741 (skeletal muscle fiber development)
Timestamp Action Category Detail
Timestamp Action Category Detail
2024-03-05 Added CONSTRAINT in_taxon NCBITaxon:6072 (Eumetazoa)
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