This term is obsolete.

GO:0045545 JSON

syndecan binding

Molecular Function

Definition (GO:0045545 GONUTS page)

Binding to syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. PMID:9355727

1,187 annotations

Ancestor Chart

Ancestor chart for GO:0045545
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Ancestor chart

Annotation Guidance

Usage of this term is subject to the following annotation guidelines:

Binding term considerations Link

Annotation Blacklist

This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:

Category Entity Type Entity ID Taxon ID Entity Name Ancestor GO ID Reason Rule/Method ID
NOT-qualified manual protein P21333-1 9606 FLNA_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684
NOT-qualified manual protein P63026 9913 VAMP2_BOVIN GO:0005515 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699
NOT-qualified manual protein Q86V48 9606 LUZP1_HUMAN GO:0005515 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684

Co-occurring Terms

These tables show the number of times the term listed in the table has been co-annotated.

No co-occurrence statistics for GO:0045545 based on ALL annotations
The top 100 of 466 co-occurring terms
Co-occurring Term PR S% #Together #Compared
syndecan binding
169,218.50 100.00 1,171 1,171
positive regulation of transforming growth factor beta receptor signaling pathway
29,605.11 16.28 820 4,687
heparanase activity
152,947.48 7.96 94 104
regulation of hair follicle development
52,845.65 6.82 94 301
peripheral nervous system axon regeneration
69,443.44 6.71 87 212
tenascin complex
53,272.49 6.27 85 270
regulation of tissue remodeling
32,130.10 5.79 90 474
heparin metabolic process
26,622.08 5.31 87 553
interleukin-5 receptor complex
166,532.50 5.29 62 63
mesenchymal-epithelial cell signaling involved in prostate gland development
84,609.25 5.18 64 128
Totals 7284 1237922
No co-occurrence statistics for GO:0045545 based on MANUAL annotations
The top 100 of 428 co-occurring terms
Co-occurring Term PR S% #Together #Compared
syndecan binding
26,139.50 100.00 54 54
tenascin complex
11,617.56 12.50 8 18
mesenchymal-epithelial cell signaling involved in prostate gland development
18,297.65 12.28 7 10
peripheral nervous system axon regeneration
6,534.87 11.90 10 40
perisynaptic extracellular matrix
6,970.53 10.53 8 30
bud outgrowth involved in lung branching
11,202.64 9.68 6 14
extracellular matrix of synaptic cleft
10,455.80 9.52 6 15
prostate gland epithelium morphogenesis
5,902.47 8.97 7 31
cellular response to prostaglandin D stimulus
8,254.58 8.96 6 19
positive regulation of transforming growth factor beta receptor signaling pathway
2,300.28 7.80 22 250
Totals 383 7683

Change Log

Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
2021-05-24 Added DEFINITION Binding to syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
2016-10-26 Added RELATION is a GO:0043394 (proteoglycan binding)
2016-10-26 Deleted RELATION is a GO:0005515 (protein binding)
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
2009-07-03 Deleted DEFINITION Interacting selectively with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
2008-05-13 Added DEFINITION Interacting selectively with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
2008-05-12 Deleted DEFINITION Interacting selectively with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
2008-04-01 Updated RELATION is a GO:0005515 (protein binding)
2003-06-10 Updated TERM syndecan binding
Timestamp Action Category Detail
2003-06-10 Updated TERM syndecan binding
2003-03-19 Updated TERM syndecan binding activity
2002-08-09 Added TERM syndecan binding
Timestamp Action Category Detail
2021-05-24 Deleted DEFINITION Interacting selectively and non-covalently with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
2021-05-24 Added DEFINITION Binding to syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
2009-07-03 Added DEFINITION Interacting selectively and non-covalently with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
2009-07-03 Deleted DEFINITION Interacting selectively with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
2008-05-13 Added DEFINITION Interacting selectively with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
2008-05-12 Deleted DEFINITION Interacting selectively with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
2003-03-26 Updated DEFINITION Interacting selectively with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
2002-11-27 Added DEFINITION Interacting selectively and stoichiometrically with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
Timestamp Action Category Detail
2016-10-26 Added RELATION is a GO:0043394 (proteoglycan binding)
2016-10-26 Deleted RELATION is a GO:0005515 (protein binding)
2008-04-01 Updated RELATION is a GO:0005515 (protein binding)
Timestamp Action Category Detail
Timestamp Action Category Detail
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