GO:0045545
JSON
syndecan binding
Molecular Function
Definition (GO:0045545 GONUTS page)
Binding to syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. PMID:9355727
Ancestor Chart
Ancestor chart for GO:0045545
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Binding term considerations | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | P21333-1 | 9606 | FLNA_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 | |
NOT-qualified manual | protein | P63026 | 9913 | VAMP2_BOVIN | GO:0005515 | 2 NOT-qualified manual annotations exist with evidence code ECO:0000353 from this reference: PMID:20702699 | |
NOT-qualified manual | protein | Q86V48 | 9606 | LUZP1_HUMAN | GO:0005515 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000353 from this reference: PMID:30990684 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0045545 based on ALL annotations
The top 100 of 466 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
syndecan binding
|
169,218.50 | 100.00 | 1,171 | 1,171 |
positive regulation of transforming growth factor beta receptor signaling pathway
|
29,605.11 | 16.28 | 820 | 4,687 |
heparanase activity
|
152,947.48 | 7.96 | 94 | 104 |
regulation of hair follicle development
|
52,845.65 | 6.82 | 94 | 301 |
peripheral nervous system axon regeneration
|
69,443.44 | 6.71 | 87 | 212 |
tenascin complex
|
53,272.49 | 6.27 | 85 | 270 |
regulation of tissue remodeling
|
32,130.10 | 5.79 | 90 | 474 |
heparin metabolic process
|
26,622.08 | 5.31 | 87 | 553 |
interleukin-5 receptor complex
|
166,532.50 | 5.29 | 62 | 63 |
mesenchymal-epithelial cell signaling involved in prostate gland development
|
84,609.25 | 5.18 | 64 | 128 |
Totals | 7284 | 1237922 |
No co-occurrence statistics for GO:0045545 based on MANUAL annotations
The top 100 of 428 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
syndecan binding
|
26,139.50 | 100.00 | 54 | 54 |
tenascin complex
|
11,617.56 | 12.50 | 8 | 18 |
mesenchymal-epithelial cell signaling involved in prostate gland development
|
18,297.65 | 12.28 | 7 | 10 |
peripheral nervous system axon regeneration
|
6,534.87 | 11.90 | 10 | 40 |
perisynaptic extracellular matrix
|
6,970.53 | 10.53 | 8 | 30 |
bud outgrowth involved in lung branching
|
11,202.64 | 9.68 | 6 | 14 |
extracellular matrix of synaptic cleft
|
10,455.80 | 9.52 | 6 | 15 |
prostate gland epithelium morphogenesis
|
5,902.47 | 8.97 | 7 | 31 |
cellular response to prostaglandin D stimulus
|
8,254.58 | 8.96 | 6 | 19 |
positive regulation of transforming growth factor beta receptor signaling pathway
|
2,300.28 | 7.80 | 22 | 250 |
Totals | 383 | 7683 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. |
2021-05-24 | Added | DEFINITION | Binding to syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. |
2016-10-26 | Added | RELATION | is a GO:0043394 (proteoglycan binding) |
2016-10-26 | Deleted | RELATION | is a GO:0005515 (protein binding) |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. |
2008-05-13 | Added | DEFINITION | Interacting selectively with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. |
2008-04-01 | Updated | RELATION | is a GO:0005515 (protein binding) |
2003-06-10 | Updated | TERM | syndecan binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-06-10 | Updated | TERM | syndecan binding |
2003-03-19 | Updated | TERM | syndecan binding activity |
2002-08-09 | Added | TERM | syndecan binding |
Timestamp | Action | Category | Detail |
---|---|---|---|
2021-05-24 | Deleted | DEFINITION | Interacting selectively and non-covalently with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. |
2021-05-24 | Added | DEFINITION | Binding to syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. |
2009-07-03 | Added | DEFINITION | Interacting selectively and non-covalently with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. |
2009-07-03 | Deleted | DEFINITION | Interacting selectively with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. |
2008-05-13 | Added | DEFINITION | Interacting selectively with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. |
2008-05-12 | Deleted | DEFINITION | Interacting selectively with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. |
2003-03-26 | Updated | DEFINITION | Interacting selectively with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. |
2002-11-27 | Added | DEFINITION | Interacting selectively and stoichiometrically with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2016-10-26 | Added | RELATION | is a GO:0043394 (proteoglycan binding) |
2016-10-26 | Deleted | RELATION | is a GO:0005515 (protein binding) |
2008-04-01 | Updated | RELATION | is a GO:0005515 (protein binding) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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