GO:0045547
JSON
dehydrodolichyl diphosphate synthase activity
Molecular Function
Definition (GO:0045547 GONUTS page)
Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate. PMID:9858571
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0045547
Child Term | Relationship to GO:0045547 |
---|---|
dehydrodolichyl diphosphate synthase complex
|
capable_of |
Annotation Guidance
Usage of this term is subject to the following annotation guidelines:
Annotating to catalytic activities using the IPI evidence code | Link |
Describing enzyme functions that catalyse multi-stage reactions | Link |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
IEA Review | protein | Q9VNA3 | 7227 | Q9VNA3_DROME | GO:0016740 | Requested by Helen Attrill. https://github.com/geneontology/go-annotation/issues/3377PMID:28597544: 'SDF2 and SDF2L1 associate with ERdj3 and act as components in the BiP chaperone cycle to prevent the aggregation of misfolded proteins.'They are not enzymes and are ER resident proteins, not membrane or extracellular proteins. | IPR016093|IPR036300 |
NOT-qualified manual | protein | P02521 | 9031 | ARLY1_CHICK | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q0E8K5 | 7227 | Q0E8K5_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7JY99 | 7227 | Q7JY99_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7KGG1 | 7227 | Q7KGG1_DROME | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:11904370 | |
NOT-qualified manual | protein | Q7KV84 | 7227 | Q7KV84_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q7SIE0 | 9103 | ARLY1_MELGA | GO:0003824 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000304 from this reference: PMID:11258884 | |
NOT-qualified manual | protein | Q7YTX2 | 7227 | Q7YTX2_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I939 | 7227 | Q8I939_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 | |
NOT-qualified manual | protein | Q8I940 | 7227 | Q8I940_DROME | GO:0016740 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000320 from this reference: PMID:16545593 |
Cross-references
Database | ID | Description |
---|---|---|
EC | 2.5.1.87 | |
RHEA | 53008 |
Cross-Ontology Relations
Relation | Other Ontology | ID | Term |
---|---|---|---|
has_participant | CHEBI | CHEBI:175763 | 2-trans,6-trans-farnesyl diphosphate(3-) |
has_participant | CHEBI | CHEBI:33019 | diphosphate(3-) |
has_participant | CHEBI | CHEBI:136960 | ditrans,polycis-polyprenyl diphosphate(3-) |
has_participant | CHEBI | CHEBI:128769 | isopentenyl diphosphate(3-) |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0045547 based on ALL annotations
The top 100 of 235 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
dehydrodolichyl diphosphate synthase activity
|
3,079.41 | 100.00 | 63,304 | 63,304 |
polyprenol biosynthetic process
|
3,079.35 | 91.09 | 57,667 | 57,668 |
di-trans,poly-cis-undecaprenyl-diphosphate synthase activity
|
3,072.68 | 43.95 | 27,847 | 27,908 |
transferase activity, transferring alkyl or aryl (other than methyl) groups
|
584.25 | 18.96 | 63,153 | 332,859 |
Z-farnesyl diphosphate synthase activity
|
3,076.83 | 17.00 | 10,764 | 10,773 |
prenyltransferase activity
|
508.30 | 15.23 | 42,040 | 254,687 |
dehydrodolichyl diphosphate synthase complex
|
3,068.99 | 11.63 | 7,368 | 7,393 |
dolichol biosynthetic process
|
1,857.03 | 8.44 | 5,656 | 9,379 |
manganese ion binding
|
78.67 | 2.30 | 12,031 | 470,951 |
magnesium ion binding
|
48.32 | 1.56 | 49,478 | 3,152,949 |
Totals | 535743 | 161589642 |
No co-occurrence statistics for GO:0045547 based on MANUAL annotations
The top 57 of 57 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
dehydrodolichyl diphosphate synthase activity
|
2,826.69 | 100.00 | 457 | 457 |
polyprenol biosynthetic process
|
2,809.24 | 70.15 | 322 | 324 |
dehydrodolichyl diphosphate synthase complex
|
2,826.69 | 35.67 | 163 | 163 |
dolichol biosynthetic process
|
1,479.60 | 23.14 | 134 | 256 |
plastid membrane organization
|
2,788.50 | 15.94 | 73 | 74 |
protein glycosylation
|
260.52 | 7.44 | 127 | 1,378 |
di-trans,poly-cis-undecaprenyl-diphosphate synthase activity
|
2,713.63 | 5.24 | 24 | 25 |
response to cold
|
143.30 | 4.00 | 73 | 1,440 |
dolichyl diphosphate biosynthetic process
|
2,355.58 | 3.26 | 15 | 18 |
chloroplast stroma
|
83.58 | 2.56 | 73 | 2,469 |
Totals | 1955 | 597550 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2023-04-02 | Added | XREF | RHEA:53008 |
2023-04-02 | Added | XREF | EC:2.5.1.87 |
2008-05-13 | Added | DEFINITION | Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate. |
2008-04-01 | Updated | RELATION | is a GO:0004659 (prenyltransferase activity) |
2003-03-19 | Updated | TERM | dehydrodolichyl diphosphate synthase activity |
2002-11-27 | Added | DEFINITION | Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate. |
2002-08-09 | Added | TERM | dehydrodolichyl diphosphate synthase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2003-03-19 | Updated | TERM | dehydrodolichyl diphosphate synthase activity |
2002-08-09 | Added | TERM | dehydrodolichyl diphosphate synthase |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-05-13 | Added | DEFINITION | Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate. |
2008-05-12 | Deleted | DEFINITION | Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate. |
2002-11-27 | Added | DEFINITION | Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0004659 (prenyltransferase activity) |
Timestamp | Action | Category | Detail |
---|---|---|---|
2023-04-02 | Added | XREF | RHEA:53008 |
2023-04-02 | Added | XREF | EC:2.5.1.87 |
Timestamp | Action | Category | Detail |
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