GO:0045671
JSON
negative regulation of osteoclast differentiation
Biological Process
Definition (GO:0045671 GONUTS page)
Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation.
Synonyms
Synonyms are alternative words or phrases closely related in meaning to the term name, with indication of the relationship between the name and synonym given by the synonym scope.
Synonym | Type |
---|---|
inhibition of osteoclast differentiation | narrow |
downregulation of osteoclast differentiation | exact |
down-regulation of osteoclast differentiation | exact |
down regulation of osteoclast differentiation | exact |
Ancestor Chart
Child Terms
This table lists all terms that are direct descendants (child terms) of GO:0045671
Child Term | Relationship to GO:0045671 |
---|---|
negative regulation of osteoclast development
|
is_a |
Annotation Blacklist
This list aims to correct incorrect annotations to UniProtKB accessions inferred from electronic annotation (IEA) methods that are supplied by the UniProt-GOA project to the GO Consortium:
Category | Entity Type | Entity ID | Taxon ID | Entity Name | Ancestor GO ID | Reason | Rule/Method ID |
---|---|---|---|---|---|---|---|
NOT-qualified manual | protein | A0A8M3AXB8 | 7955 | A0A8M3AXB8_DANRE | GO:0045637 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:15621534 | |
NOT-qualified manual | protein | A0A8M9Q709 | 7955 | A0A8M9Q709_DANRE | GO:0045637 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:15621534 | |
NOT-qualified manual | protein | Q7T3G1 | 7955 | Q7T3G1_DANRE | GO:0045637 | 1 NOT-qualified manual annotation exists with evidence code ECO:0000315 from this reference: PMID:15621534 |
Co-occurring Terms
These tables show the number of times the term listed in the table has been co-annotated.
No co-occurrence statistics for GO:0045671 based on ALL annotations
The top 100 of 1,234 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of osteoclast differentiation
|
55,286.10 | 100.00 | 3,526 | 3,526 |
negative regulation of bone resorption
|
23,133.23 | 28.90 | 1,703 | 4,070 |
osteoclast differentiation
|
3,409.68 | 4.41 | 471 | 7,637 |
myeloid leukocyte migration
|
26,702.81 | 3.86 | 142 | 294 |
dorsal/ventral axis specification
|
7,781.01 | 3.74 | 171 | 1,215 |
positive regulation of TORC1 signaling
|
2,081.62 | 3.57 | 1,438 | 38,192 |
regulation of osteoclast differentiation
|
5,718.16 | 3.55 | 181 | 1,750 |
bone resorption
|
3,792.54 | 3.48 | 232 | 3,382 |
negative regulation of osteoblast differentiation
|
3,372.72 | 3.42 | 255 | 4,180 |
negative regulation of protein sumoylation
|
6,541.01 | 3.34 | 157 | 1,327 |
Totals | 16425 | 105775 |
No co-occurrence statistics for GO:0045671 based on MANUAL annotations
The top 100 of 1,114 co-occurring terms
Co-occurring Term | PR | S% | #Together | #Compared |
---|---|---|---|---|
negative regulation of osteoclast differentiation
|
7,781.92 | 100.00 | 166 | 166 |
negative regulation of bone resorption
|
3,813.14 | 22.58 | 49 | 100 |
eosinophil degranulation
|
4,669.15 | 10.11 | 18 | 30 |
positive regulation of natural killer cell chemotaxis
|
4,669.15 | 10.11 | 18 | 30 |
lymphocyte chemotaxis
|
3,112.77 | 9.33 | 18 | 45 |
granulocyte chemotaxis
|
2,918.22 | 9.18 | 18 | 48 |
astrocyte cell migration
|
3,307.32 | 8.99 | 17 | 40 |
phospholipase activator activity
|
2,415.08 | 8.74 | 18 | 58 |
T cell chemotaxis
|
2,334.58 | 8.65 | 18 | 60 |
negative regulation by host of viral transcription
|
2,223.41 | 8.53 | 18 | 63 |
Totals | 1337 | 15315 |
Change Log
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Timestamp | Action | Category | Detail |
---|---|---|---|
2010-10-03 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation. |
2010-10-03 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast differentiation. |
2008-05-13 | Added | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast differentiation. |
2008-05-12 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast differentiation. |
2008-04-01 | Updated | RELATION | is a GO:0045670 (regulation of osteoclast differentiation) |
2008-04-01 | Updated | RELATION | is a GO:0002762 (negative regulation of myeloid leukocyte differentiation) |
2008-04-01 | Added | RELATION | negatively regulates GO:0030316 (osteoclast differentiation) |
2007-08-09 | Added | SYNONYM | inhibition of osteoclast differentiation |
2007-08-09 | Added | SYNONYM | downregulation of osteoclast differentiation |
2007-08-09 | Added | SYNONYM | down-regulation of osteoclast differentiation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2002-08-14 | Added | TERM | negative regulation of osteoclast differentiation |
Timestamp | Action | Category | Detail |
---|---|---|---|
2010-10-03 | Added | DEFINITION | Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation. |
2010-10-03 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast differentiation. |
2008-05-13 | Added | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast differentiation. |
2008-05-12 | Deleted | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast differentiation. |
2007-08-09 | Added | SYNONYM | inhibition of osteoclast differentiation |
2007-08-09 | Added | SYNONYM | downregulation of osteoclast differentiation |
2007-08-09 | Added | SYNONYM | down-regulation of osteoclast differentiation |
2007-08-09 | Added | SYNONYM | down regulation of osteoclast differentiation |
2007-08-09 | Deleted | SYNONYM | down-regulation of osteoclast differentiation |
2007-08-09 | Deleted | SYNONYM | down regulation of osteoclast differentiation |
2007-08-09 | Deleted | SYNONYM | inhibition of osteoclast differentiation |
2007-08-09 | Deleted | SYNONYM | downregulation of osteoclast differentiation |
2007-02-23 | Added | SYNONYM | down regulation of osteoclast differentiation |
2007-02-23 | Added | SYNONYM | inhibition of osteoclast differentiation |
2007-02-23 | Added | SYNONYM | down-regulation of osteoclast differentiation |
2007-02-23 | Added | SYNONYM | downregulation of osteoclast differentiation |
2006-05-04 | Updated | DEFINITION | Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast differentiation. |
2005-10-21 | Updated | DEFINITION | Any process that stops, prevents or reduces the rate, frequency or extent of osteoclast differentiation. |
2002-11-27 | Added | DEFINITION | Any process that stops, prevents or reduces the rate of osteoclast differentiation. |
Timestamp | Action | Category | Detail |
---|---|---|---|
2008-04-01 | Updated | RELATION | is a GO:0045670 (regulation of osteoclast differentiation) |
2008-04-01 | Updated | RELATION | is a GO:0002762 (negative regulation of myeloid leukocyte differentiation) |
2008-04-01 | Added | RELATION | negatively regulates GO:0030316 (osteoclast differentiation) |
Timestamp | Action | Category | Detail |
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Timestamp | Action | Category | Detail |
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